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Updated November 2019
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Protein Info
Short Name:
NOBOX
Full Name:
Homeobox protein NOBOX
Alias:
Type:
Mass (Da):
73906
Number AA:
691
UniProt ID:
O60393
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T67
C
S
L
C
A
L
E
T
L
K
S
P
Q
H
D
Site 2
S70
C
A
L
E
T
L
K
S
P
Q
H
D
P
L
E
Site 3
S90
L
K
L
I
P
L
V
S
G
K
R
E
L
T
R
Site 4
T96
V
S
G
K
R
E
L
T
R
G
Q
K
A
G
E
Site 5
S119
E
E
E
L
L
R
G
S
A
P
H
A
Q
D
T
Site 6
T126
S
A
P
H
A
Q
D
T
Q
S
E
E
L
P
P
Site 7
S128
P
H
A
Q
D
T
Q
S
E
E
L
P
P
S
C
Site 8
S134
Q
S
E
E
L
P
P
S
C
T
I
S
G
E
K
Site 9
T136
E
E
L
P
P
S
C
T
I
S
G
E
K
K
P
Site 10
S138
L
P
P
S
C
T
I
S
G
E
K
K
P
P
A
Site 11
T151
P
A
V
S
G
E
A
T
G
A
D
A
G
R
L
Site 12
S164
R
L
C
P
P
P
R
S
R
A
P
H
K
D
R
Site 13
T172
R
A
P
H
K
D
R
T
L
A
R
S
R
P
Q
Site 14
S176
K
D
R
T
L
A
R
S
R
P
Q
T
Q
G
E
Site 15
T180
L
A
R
S
R
P
Q
T
Q
G
E
D
C
S
L
Site 16
S186
Q
T
Q
G
E
D
C
S
L
P
V
G
E
V
K
Site 17
S198
E
V
K
I
G
K
R
S
Y
S
P
A
P
G
K
Site 18
Y199
V
K
I
G
K
R
S
Y
S
P
A
P
G
K
Q
Site 19
S200
K
I
G
K
R
S
Y
S
P
A
P
G
K
Q
K
Site 20
S218
A
M
G
L
A
P
T
S
S
P
G
A
P
N
S
Site 21
S219
M
G
L
A
P
T
S
S
P
G
A
P
N
S
A
Site 22
S225
S
S
P
G
A
P
N
S
A
R
A
T
H
N
P
Site 23
T229
A
P
N
S
A
R
A
T
H
N
P
V
P
C
G
Site 24
S237
H
N
P
V
P
C
G
S
G
R
G
P
C
H
L
Site 25
S249
C
H
L
A
N
L
L
S
T
L
A
Q
S
N
Q
Site 26
T250
H
L
A
N
L
L
S
T
L
A
Q
S
N
Q
N
Site 27
T268
K
Q
G
P
P
E
V
T
C
Q
I
R
K
K
T
Site 28
T275
T
C
Q
I
R
K
K
T
R
T
L
Y
R
S
D
Site 29
T277
Q
I
R
K
K
T
R
T
L
Y
R
S
D
Q
L
Site 30
Y279
R
K
K
T
R
T
L
Y
R
S
D
Q
L
E
E
Site 31
S281
K
T
R
T
L
Y
R
S
D
Q
L
E
E
L
E
Site 32
Y296
K
I
F
Q
E
D
H
Y
P
D
S
D
K
R
R
Site 33
S299
Q
E
D
H
Y
P
D
S
D
K
R
R
E
I
A
Site 34
T308
K
R
R
E
I
A
Q
T
V
G
V
T
P
Q
R
Site 35
T337
G
G
G
P
T
I
E
T
L
E
L
Q
S
E
R
Site 36
S381
P
A
A
P
G
P
A
S
S
Q
C
S
S
A
A
Site 37
S382
A
A
P
G
P
A
S
S
Q
C
S
S
A
A
E
Site 38
S385
G
P
A
S
S
Q
C
S
S
A
A
E
I
L
P
Site 39
S407
P
D
P
F
P
Q
E
S
P
L
D
T
F
P
E
Site 40
T411
P
Q
E
S
P
L
D
T
F
P
E
P
P
M
L
Site 41
S421
E
P
P
M
L
L
T
S
D
Q
T
L
A
P
T
Site 42
T424
M
L
L
T
S
D
Q
T
L
A
P
T
Q
P
S
Site 43
T428
S
D
Q
T
L
A
P
T
Q
P
S
E
G
A
Q
Site 44
T439
E
G
A
Q
R
V
V
T
P
P
L
F
S
P
P
Site 45
S475
L
L
M
D
V
A
G
S
D
S
S
H
K
D
G
Site 46
S477
M
D
V
A
G
S
D
S
S
H
K
D
G
P
C
Site 47
S478
D
V
A
G
S
D
S
S
H
K
D
G
P
C
G
Site 48
S486
H
K
D
G
P
C
G
S
W
G
T
S
I
T
L
Site 49
T492
G
S
W
G
T
S
I
T
L
P
P
P
C
S
Y
Site 50
S498
I
T
L
P
P
P
C
S
Y
L
E
E
L
E
P
Site 51
Y508
E
E
L
E
P
Q
D
Y
Q
Q
S
N
Q
P
G
Site 52
S511
E
P
Q
D
Y
Q
Q
S
N
Q
P
G
P
F
Q
Site 53
S520
Q
P
G
P
F
Q
F
S
Q
A
P
Q
P
P
L
Site 54
S530
P
Q
P
P
L
F
Q
S
P
Q
P
K
L
P
Y
Site 55
Y537
S
P
Q
P
K
L
P
Y
L
P
T
F
P
F
S
Site 56
T540
P
K
L
P
Y
L
P
T
F
P
F
S
M
P
S
Site 57
S548
F
P
F
S
M
P
S
S
L
T
L
P
P
P
E
Site 58
T550
F
S
M
P
S
S
L
T
L
P
P
P
E
D
S
Site 59
S566
F
M
F
P
C
G
P
S
G
G
T
S
Q
G
Y
Site 60
S570
C
G
P
S
G
G
T
S
Q
G
Y
C
P
G
A
Site 61
Y573
S
G
G
T
S
Q
G
Y
C
P
G
A
S
S
G
Site 62
T593
P
P
A
G
N
I
G
T
A
S
W
S
D
P
C
Site 63
S595
A
G
N
I
G
T
A
S
W
S
D
P
C
L
P
Site 64
S597
N
I
G
T
A
S
W
S
D
P
C
L
P
E
L
Site 65
Y624
H
P
P
G
G
D
G
Y
F
P
D
L
F
P
T
Site 66
S642
Q
A
L
G
R
Q
P
S
S
A
L
S
W
M
P
Site 67
S643
A
L
G
R
Q
P
S
S
A
L
S
W
M
P
E
Site 68
S646
R
Q
P
S
S
A
L
S
W
M
P
E
G
A
R
Site 69
T656
P
E
G
A
R
P
G
T
G
P
L
L
S
K
A
Site 70
S661
P
G
T
G
P
L
L
S
K
A
K
E
E
P
P
Site 71
S671
K
E
E
P
P
A
A
S
L
D
Q
P
S
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation