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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ONECUT3
Full Name:
One cut domain family member 3
Alias:
One cut homeobox 3;Transcription factor ONECUT-3
Type:
Mass (Da):
50037
Number AA:
494
UniProt ID:
O60422
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
E
S
L
G
G
L
H
S
V
A
H
A
Q
A
G
Site 2
S24
A
Q
A
G
E
L
L
S
P
G
H
A
R
S
A
Site 3
S30
L
S
P
G
H
A
R
S
A
A
A
Q
H
R
G
Site 4
T106
P
G
L
G
G
T
Y
T
T
L
T
P
L
Q
H
Site 5
T109
G
G
T
Y
T
T
L
T
P
L
Q
H
L
P
P
Site 6
T169
A
S
V
S
G
S
F
T
L
M
R
D
E
R
A
Site 7
S180
D
E
R
A
A
L
A
S
V
G
H
L
Y
G
P
Site 8
Y185
L
A
S
V
G
H
L
Y
G
P
Y
G
K
E
L
Site 9
Y188
V
G
H
L
Y
G
P
Y
G
K
E
L
P
A
M
Site 10
S197
K
E
L
P
A
M
G
S
P
L
S
P
L
P
N
Site 11
Y228
P
P
P
P
L
A
A
Y
G
P
P
G
H
L
A
Site 12
S272
G
G
G
G
G
T
G
S
G
G
A
G
S
G
S
Site 13
S308
G
G
G
G
P
G
G
S
G
G
G
P
S
A
G
Site 14
T323
A
A
A
E
E
I
N
T
K
E
V
A
Q
R
I
Site 15
T331
K
E
V
A
Q
R
I
T
A
E
L
K
R
Y
S
Site 16
Y337
I
T
A
E
L
K
R
Y
S
I
P
Q
A
I
F
Site 17
S338
T
A
E
L
K
R
Y
S
I
P
Q
A
I
F
A
Site 18
S352
A
Q
R
I
L
C
R
S
Q
G
T
L
S
D
L
Site 19
T355
I
L
C
R
S
Q
G
T
L
S
D
L
L
R
N
Site 20
S357
C
R
S
Q
G
T
L
S
D
L
L
R
N
P
K
Site 21
S367
L
R
N
P
K
P
W
S
K
L
K
S
G
R
E
Site 22
S371
K
P
W
S
K
L
K
S
G
R
E
T
F
R
R
Site 23
T375
K
L
K
S
G
R
E
T
F
R
R
M
W
K
W
Site 24
S392
E
P
E
F
Q
R
M
S
A
L
R
L
A
A
C
Site 25
T428
F
T
D
L
Q
R
R
T
L
I
A
I
F
K
E
Site 26
S440
F
K
E
N
K
R
P
S
K
E
M
Q
V
T
I
Site 27
T446
P
S
K
E
M
Q
V
T
I
S
Q
Q
L
G
L
Site 28
S448
K
E
M
Q
V
T
I
S
Q
Q
L
G
L
E
L
Site 29
S459
G
L
E
L
N
T
V
S
N
F
F
M
N
A
R
Site 30
S478
N
R
W
A
E
E
P
S
T
A
P
G
G
P
A
Site 31
T479
R
W
A
E
E
P
S
T
A
P
G
G
P
A
G
Site 32
T488
P
G
G
P
A
G
A
T
A
T
F
S
K
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation