PhosphoNET

           
Protein Info 
   
Short Name:  DFNA5
Full Name:  Non-syndromic hearing impairment protein 5
Alias:  Deafness, autosomal dominant 5; Deafness, autosomal dominant 5 protein; ICERE1; ICERE-1; Inversely correlated with estrogen receptor expression 1; Nonsyndromic hearing impairment protein; Nonsyndromic hearing impairment protein 5
Type:  Uncharacterized protein
Mass (Da):  54555
Number AA:  496
UniProt ID:  O60443
International Prot ID:  IPI00029656
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0003008  GO:0007600  GO:0007605 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S23DGDLIAVSNLNDSDK
Site 2S28AVSNLNDSDKLQLLS
Site 3S35SDKLQLLSLVTKKKR
Site 4Y51WCWQRPKYQFLSLTL
Site 5S69LIEDQFPSPVVVESD
Site 6S75PSPVVVESDFVKYEG
Site 7Y80VESDFVKYEGKFANH
Site 8S89GKFANHVSGTLETAL
Site 9S106VKLNLGGSSRVESQS
Site 10S107KLNLGGSSRVESQSS
Site 11S111GGSSRVESQSSFGTL
Site 12S113SSRVESQSSFGTLRK
Site 13S114SRVESQSSFGTLRKQ
Site 14T117ESQSSFGTLRKQEVD
Site 15S132LQQLIRDSAERTINL
Site 16T136IRDSAERTINLRNPV
Site 17S205DGNVTKDSNVVLEIP
Site 18S252ENKKRIDSVYLDPLV
Site 19Y254KKRIDSVYLDPLVFR
Site 20S277DAAHGISSQDGPLSV
Site 21S283SSQDGPLSVLKQATL
Site 22T308ELPEPQQTALSDIFQ
Site 23S379PGPEDAGSKQLFMTA
Site 24S429ALSDDGVSDLEDPTL
Site 25T435VSDLEDPTLTPLKDT
Site 26T437DLEDPTLTPLKDTER
Site 27T442TLTPLKDTERFGIVQ
Site 28S458LFASADISLERLKSS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation