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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAN1A2
Full Name:
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
Alias:
Mannosidase alpha class 1A member 2;Processing alpha-1,2-mannosidase IB
Type:
Mass (Da):
73004
Number AA:
641
UniProt ID:
O60476
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
T
P
A
L
L
P
L
Site 2
T3
_
_
_
_
_
M
T
T
P
A
L
L
P
L
S
Site 3
S23
P
L
N
L
G
P
P
S
F
P
H
H
R
A
T
Site 4
T30
S
F
P
H
H
R
A
T
L
R
L
S
E
K
F
Site 5
S60
A
F
F
F
L
P
D
S
S
K
H
K
R
F
D
Site 6
S129
A
K
E
K
L
R
K
S
R
E
E
I
R
A
E
Site 7
T139
E
I
R
A
E
I
Q
T
E
K
N
K
V
V
Q
Site 8
S214
P
I
A
R
K
G
H
S
P
N
I
F
G
S
S
Site 9
S257
I
E
D
N
L
D
F
S
V
N
S
E
V
S
V
Site 10
S327
G
R
N
W
G
W
A
S
A
G
S
S
I
L
A
Site 11
T354
S
Y
L
T
G
D
L
T
Y
Y
K
K
V
M
H
Site 12
Y355
Y
L
T
G
D
L
T
Y
Y
K
K
V
M
H
I
Site 13
Y356
L
T
G
D
L
T
Y
Y
K
K
V
M
H
I
R
Site 14
Y376
M
D
R
P
N
G
L
Y
P
N
Y
L
N
P
R
Site 15
Y379
P
N
G
L
Y
P
N
Y
L
N
P
R
T
G
R
Site 16
Y390
R
T
G
R
W
G
Q
Y
H
T
S
V
G
G
L
Site 17
T392
G
R
W
G
Q
Y
H
T
S
V
G
G
L
G
D
Site 18
S393
R
W
G
Q
Y
H
T
S
V
G
G
L
G
D
S
Site 19
S400
S
V
G
G
L
G
D
S
F
Y
E
Y
L
L
K
Site 20
Y402
G
G
L
G
D
S
F
Y
E
Y
L
L
K
A
W
Site 21
T415
A
W
L
M
S
D
K
T
D
H
E
A
R
K
M
Site 22
Y423
D
H
E
A
R
K
M
Y
D
D
A
I
E
A
I
Site 23
S438
E
K
H
L
I
K
K
S
R
G
G
L
T
F
I
Site 24
T443
K
K
S
R
G
G
L
T
F
I
G
E
W
K
N
Site 25
S475
F
A
L
G
A
D
G
S
R
A
D
K
A
G
H
Site 26
Y483
R
A
D
K
A
G
H
Y
L
E
L
G
A
E
I
Site 27
T493
L
G
A
E
I
A
R
T
C
H
E
S
Y
D
R
Site 28
S497
I
A
R
T
C
H
E
S
Y
D
R
T
A
L
K
Site 29
Y498
A
R
T
C
H
E
S
Y
D
R
T
A
L
K
L
Site 30
T501
C
H
E
S
Y
D
R
T
A
L
K
L
G
P
E
Site 31
Y527
A
V
R
Q
A
E
K
Y
Y
I
L
R
P
E
V
Site 32
Y578
F
S
G
V
K
D
V
Y
S
S
T
P
T
H
D
Site 33
S579
S
G
V
K
D
V
Y
S
S
T
P
T
H
D
D
Site 34
T581
V
K
D
V
Y
S
S
T
P
T
H
D
D
V
Q
Site 35
T583
D
V
Y
S
S
T
P
T
H
D
D
V
Q
Q
S
Site 36
S590
T
H
D
D
V
Q
Q
S
F
F
L
A
E
T
L
Site 37
Y601
A
E
T
L
K
Y
L
Y
L
L
F
S
G
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation