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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DBC1
Full Name:
Deleted in bladder cancer protein 1
Alias:
Protein FAM5A
Type:
Mass (Da):
88760
Number AA:
761
UniProt ID:
O60477
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
L
F
I
W
G
R
I
S
V
Q
P
S
H
Q
E
Site 2
S23
G
R
I
S
V
Q
P
S
H
Q
E
P
A
G
T
Site 3
T30
S
H
Q
E
P
A
G
T
D
Q
H
V
S
K
E
Site 4
S51
D
R
G
P
F
H
H
S
R
S
Y
L
S
F
V
Site 5
S53
G
P
F
H
H
S
R
S
Y
L
S
F
V
E
R
Site 6
Y54
P
F
H
H
S
R
S
Y
L
S
F
V
E
R
H
Site 7
S56
H
H
S
R
S
Y
L
S
F
V
E
R
H
R
Q
Site 8
T66
E
R
H
R
Q
G
F
T
T
R
Y
K
I
Y
R
Site 9
T67
R
H
R
Q
G
F
T
T
R
Y
K
I
Y
R
E
Site 10
Y69
R
Q
G
F
T
T
R
Y
K
I
Y
R
E
F
A
Site 11
T83
A
R
W
K
V
R
N
T
A
I
E
R
R
D
L
Site 12
S104
L
M
P
E
F
Q
R
S
I
R
L
L
G
R
R
Site 13
T113
R
L
L
G
R
R
P
T
T
Q
Q
F
I
D
T
Site 14
T114
L
L
G
R
R
P
T
T
Q
Q
F
I
D
T
I
Site 15
T142
L
G
G
E
E
A
L
T
M
Y
M
D
K
S
R
Site 16
Y144
G
E
E
A
L
T
M
Y
M
D
K
S
R
L
D
Site 17
S148
L
T
M
Y
M
D
K
S
R
L
D
R
K
S
G
Site 18
S154
K
S
R
L
D
R
K
S
G
N
A
T
Q
S
V
Site 19
T158
D
R
K
S
G
N
A
T
Q
S
V
E
A
L
H
Site 20
S160
K
S
G
N
A
T
Q
S
V
E
A
L
H
Q
L
Site 21
S169
E
A
L
H
Q
L
A
S
S
Y
F
V
D
R
D
Site 22
Y171
L
H
Q
L
A
S
S
Y
F
V
D
R
D
G
T
Site 23
T178
Y
F
V
D
R
D
G
T
M
R
R
L
H
E
I
Site 24
T195
S
T
G
A
I
K
V
T
E
T
R
T
G
P
L
Site 25
S206
T
G
P
L
G
C
N
S
Y
D
N
L
D
S
V
Site 26
Y207
G
P
L
G
C
N
S
Y
D
N
L
D
S
V
S
Site 27
S212
N
S
Y
D
N
L
D
S
V
S
S
V
L
L
Q
Site 28
S214
Y
D
N
L
D
S
V
S
S
V
L
L
Q
S
T
Site 29
S215
D
N
L
D
S
V
S
S
V
L
L
Q
S
T
E
Site 30
T221
S
S
V
L
L
Q
S
T
E
S
K
L
H
L
Q
Site 31
Y258
M
C
N
G
E
G
E
Y
L
C
Q
N
S
Q
C
Site 32
S307
A
Y
K
D
L
E
N
S
D
E
F
K
S
F
M
Site 33
S312
E
N
S
D
E
F
K
S
F
M
K
R
L
P
S
Site 34
S319
S
F
M
K
R
L
P
S
N
H
F
L
T
I
G
Site 35
T324
L
P
S
N
H
F
L
T
I
G
S
I
H
Q
H
Site 36
T359
Q
R
Q
K
I
Q
R
T
A
R
K
L
F
G
L
Site 37
S367
A
R
K
L
F
G
L
S
V
R
C
R
H
N
P
Site 38
T383
H
Q
L
P
R
E
R
T
I
Q
Q
W
L
A
R
Site 39
Y396
A
R
V
Q
S
L
L
Y
C
N
E
N
G
F
W
Site 40
T405
N
E
N
G
F
W
G
T
F
L
E
S
Q
R
S
Site 41
S412
T
F
L
E
S
Q
R
S
C
V
C
H
G
S
T
Site 42
S449
A
N
I
S
L
C
G
S
C
N
K
G
Y
K
L
Site 43
Y454
C
G
S
C
N
K
G
Y
K
L
Y
R
G
R
C
Site 44
S468
C
E
P
Q
N
V
D
S
E
R
S
E
Q
F
I
Site 45
S476
E
R
S
E
Q
F
I
S
F
E
T
D
L
D
F
Site 46
Y490
F
Q
D
L
E
L
K
Y
L
L
Q
K
M
D
S
Site 47
Y500
Q
K
M
D
S
R
L
Y
V
H
T
T
F
I
S
Site 48
T503
D
S
R
L
Y
V
H
T
T
F
I
S
N
E
I
Site 49
T504
S
R
L
Y
V
H
T
T
F
I
S
N
E
I
R
Site 50
T514
S
N
E
I
R
L
D
T
F
F
D
P
R
W
R
Site 51
S525
P
R
W
R
K
R
M
S
L
T
L
K
S
N
K
Site 52
T527
W
R
K
R
M
S
L
T
L
K
S
N
K
N
R
Site 53
S530
R
M
S
L
T
L
K
S
N
K
N
R
M
D
F
Site 54
S568
F
V
Y
V
N
P
F
S
G
S
H
S
E
G
W
Site 55
Y584
M
P
F
G
E
F
G
Y
P
R
W
E
K
I
R
Site 56
Y618
F
F
E
T
V
H
I
Y
L
R
S
R
T
R
L
Site 57
T623
H
I
Y
L
R
S
R
T
R
L
P
T
L
L
R
Site 58
T627
R
S
R
T
R
L
P
T
L
L
R
N
E
T
G
Site 59
T633
P
T
L
L
R
N
E
T
G
Q
G
P
V
D
L
Site 60
S641
G
Q
G
P
V
D
L
S
D
P
S
K
R
Q
F
Site 61
S644
P
V
D
L
S
D
P
S
K
R
Q
F
Y
I
K
Site 62
Y649
D
P
S
K
R
Q
F
Y
I
K
I
S
D
V
Q
Site 63
Y660
S
D
V
Q
V
F
G
Y
S
L
R
F
N
A
D
Site 64
S679
A
V
Q
Q
V
N
Q
S
Y
T
Q
G
G
Q
F
Site 65
Y680
V
Q
Q
V
N
Q
S
Y
T
Q
G
G
Q
F
Y
Site 66
Y687
Y
T
Q
G
G
Q
F
Y
S
S
S
S
V
M
L
Site 67
S688
T
Q
G
G
Q
F
Y
S
S
S
S
V
M
L
L
Site 68
S721
K
P
Q
L
D
L
F
S
C
M
L
K
H
R
L
Site 69
T731
L
K
H
R
L
K
L
T
N
S
E
I
I
R
V
Site 70
S733
H
R
L
K
L
T
N
S
E
I
I
R
V
N
H
Site 71
Y745
V
N
H
A
L
D
L
Y
N
T
E
I
L
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation