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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZIC3
Full Name:
Zinc finger protein ZIC 3
Alias:
Zinc finger protein 203;Zinc finger protein of the cerebellum 3
Type:
Nucleus protein
Mass (Da):
50569
Number AA:
467
UniProt ID:
O60481
International Prot ID:
IPI00029724
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007368
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
F
P
G
L
G
V
G
S
F
G
A
P
R
H
H
Site 2
S67
P
A
A
A
H
D
L
S
S
G
Q
S
S
A
F
Site 3
S68
A
A
A
H
D
L
S
S
G
Q
S
S
A
F
T
Site 4
S71
H
D
L
S
S
G
Q
S
S
A
F
T
P
Q
G
Site 5
S72
D
L
S
S
G
Q
S
S
A
F
T
P
Q
G
S
Site 6
T75
S
G
Q
S
S
A
F
T
P
Q
G
S
G
Y
A
Site 7
S79
S
A
F
T
P
Q
G
S
G
Y
A
N
A
L
G
Site 8
Y81
F
T
P
Q
G
S
G
Y
A
N
A
L
G
H
H
Site 9
S103
H
H
T
S
Q
V
P
S
Y
G
G
A
A
S
A
Site 10
S109
P
S
Y
G
G
A
A
S
A
A
F
N
S
T
R
Site 11
S114
A
A
S
A
A
F
N
S
T
R
E
F
L
F
R
Site 12
S124
E
F
L
F
R
Q
R
S
S
G
L
S
E
A
A
Site 13
S125
F
L
F
R
Q
R
S
S
G
L
S
E
A
A
S
Site 14
S128
R
Q
R
S
S
G
L
S
E
A
A
S
G
G
G
Site 15
S132
S
G
L
S
E
A
A
S
G
G
G
Q
H
G
L
Site 16
S143
Q
H
G
L
F
A
G
S
A
S
S
L
H
A
P
Site 17
S174
E
Q
G
A
G
H
P
S
P
T
G
H
V
D
N
Site 18
Y199
L
F
G
R
A
D
P
Y
R
P
V
A
S
P
R
Site 19
S204
D
P
Y
R
P
V
A
S
P
R
T
D
P
Y
A
Site 20
Y210
A
S
P
R
T
D
P
Y
A
A
G
A
Q
F
P
Site 21
Y219
A
G
A
Q
F
P
N
Y
S
P
M
N
M
N
M
Site 22
Y242
G
P
G
A
F
F
R
Y
M
R
Q
P
I
K
Q
Site 23
S262
W
I
D
E
A
Q
L
S
R
P
K
K
S
C
D
Site 24
S267
Q
L
S
R
P
K
K
S
C
D
R
T
F
S
T
Site 25
T271
P
K
K
S
C
D
R
T
F
S
T
M
H
E
L
Site 26
S273
K
S
C
D
R
T
F
S
T
M
H
E
L
V
T
Site 27
S308
E
C
P
R
E
G
K
S
F
K
A
K
Y
K
L
Site 28
Y313
G
K
S
F
K
A
K
Y
K
L
V
N
H
I
R
Site 29
T323
V
N
H
I
R
V
H
T
G
E
K
P
F
P
C
Site 30
S342
C
G
K
I
F
A
R
S
E
N
L
K
I
H
K
Site 31
T351
N
L
K
I
H
K
R
T
H
T
G
E
K
P
F
Site 32
T353
K
I
H
K
R
T
H
T
G
E
K
P
F
K
C
Site 33
S372
C
D
R
R
F
A
N
S
S
D
R
K
K
H
M
Site 34
S373
D
R
R
F
A
N
S
S
D
R
K
K
H
M
H
Site 35
Y388
V
H
T
S
D
K
P
Y
I
C
K
V
C
D
K
Site 36
Y397
C
K
V
C
D
K
S
Y
T
H
P
S
S
L
R
Site 37
T398
K
V
C
D
K
S
Y
T
H
P
S
S
L
R
K
Site 38
S401
D
K
S
Y
T
H
P
S
S
L
R
K
H
M
K
Site 39
S402
K
S
Y
T
H
P
S
S
L
R
K
H
M
K
V
Site 40
S412
K
H
M
K
V
H
E
S
Q
G
S
D
S
S
P
Site 41
S415
K
V
H
E
S
Q
G
S
D
S
S
P
A
A
S
Site 42
S417
H
E
S
Q
G
S
D
S
S
P
A
A
S
S
G
Site 43
S418
E
S
Q
G
S
D
S
S
P
A
A
S
S
G
Y
Site 44
S422
S
D
S
S
P
A
A
S
S
G
Y
E
S
S
T
Site 45
S423
D
S
S
P
A
A
S
S
G
Y
E
S
S
T
P
Site 46
Y425
S
P
A
A
S
S
G
Y
E
S
S
T
P
P
A
Site 47
S427
A
A
S
S
G
Y
E
S
S
T
P
P
A
I
A
Site 48
S428
A
S
S
G
Y
E
S
S
T
P
P
A
I
A
S
Site 49
T429
S
S
G
Y
E
S
S
T
P
P
A
I
A
S
A
Site 50
S435
S
T
P
P
A
I
A
S
A
N
S
K
D
T
T
Site 51
T442
S
A
N
S
K
D
T
T
K
T
P
S
A
V
Q
Site 52
T444
N
S
K
D
T
T
K
T
P
S
A
V
Q
T
S
Site 53
S446
K
D
T
T
K
T
P
S
A
V
Q
T
S
T
S
Site 54
T450
K
T
P
S
A
V
Q
T
S
T
S
H
N
P
G
Site 55
S453
S
A
V
Q
T
S
T
S
H
N
P
G
L
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation