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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLXNC1
Full Name:
Plexin-C1
Alias:
CD232; Plexin C1; PLXC1; VESPR; Virus-encoded semaphorin protein receptor
Type:
Adhesion
Mass (Da):
175742
Number AA:
1568
UniProt ID:
O60486
International Prot ID:
IPI00024766
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004872
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007275
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y438
P
D
P
V
K
N
I
Y
I
Y
L
T
A
G
K
Site 2
Y440
P
V
K
N
I
Y
I
Y
L
T
A
G
K
E
V
Site 3
S970
V
G
V
T
R
H
K
S
K
E
L
S
R
K
Q
Site 4
S974
R
H
K
S
K
E
L
S
R
K
Q
S
Q
Q
L
Site 5
S978
K
E
L
S
R
K
Q
S
Q
Q
L
E
L
L
E
Site 6
S986
Q
Q
L
E
L
L
E
S
E
L
R
K
E
I
R
Site 7
Y1018
G
T
V
P
F
L
D
Y
K
H
F
A
L
R
T
Site 8
T1025
Y
K
H
F
A
L
R
T
F
F
P
E
S
G
G
Site 9
T1034
F
P
E
S
G
G
F
T
H
I
F
T
E
D
M
Site 10
S1052
D
A
N
D
K
N
E
S
L
T
A
L
D
A
L
Site 11
T1129
P
K
L
M
L
R
R
T
E
S
V
V
E
K
L
Site 12
S1146
N
W
M
S
V
C
L
S
G
F
L
R
E
T
V
Site 13
T1229
V
N
V
L
D
C
D
T
I
G
Q
A
K
E
K
Site 14
S1243
K
I
F
Q
A
F
L
S
K
N
G
S
P
Y
G
Site 15
S1247
A
F
L
S
K
N
G
S
P
Y
G
L
Q
L
N
Site 16
S1274
K
E
L
L
D
I
D
S
S
S
V
I
L
E
D
Site 17
Y1292
K
L
N
T
I
G
H
Y
E
I
S
N
G
S
T
Site 18
S1295
T
I
G
H
Y
E
I
S
N
G
S
T
I
K
V
Site 19
S1311
K
K
I
A
N
F
T
S
D
V
E
Y
S
D
D
Site 20
Y1315
N
F
T
S
D
V
E
Y
S
D
D
H
C
H
L
Site 21
S1327
C
H
L
I
L
P
D
S
E
A
F
Q
D
V
Q
Site 22
Y1350
K
F
K
V
K
E
M
Y
L
T
K
L
L
S
T
Site 23
T1352
K
V
K
E
M
Y
L
T
K
L
L
S
T
K
V
Site 24
S1371
V
L
E
K
L
F
R
S
I
W
S
L
P
N
S
Site 25
S1374
K
L
F
R
S
I
W
S
L
P
N
S
R
A
P
Site 26
S1378
S
I
W
S
L
P
N
S
R
A
P
F
A
I
K
Site 27
S1454
Q
A
F
M
D
A
F
S
L
T
E
Q
Q
L
G
Site 28
T1466
Q
L
G
K
E
A
P
T
N
K
L
L
Y
A
K
Site 29
Y1471
A
P
T
N
K
L
L
Y
A
K
D
I
P
T
Y
Site 30
Y1478
Y
A
K
D
I
P
T
Y
K
E
E
V
K
S
Y
Site 31
S1484
T
Y
K
E
E
V
K
S
Y
Y
K
A
I
R
D
Site 32
Y1485
Y
K
E
E
V
K
S
Y
Y
K
A
I
R
D
L
Site 33
S1496
I
R
D
L
P
P
L
S
S
S
E
M
E
E
F
Site 34
S1497
R
D
L
P
P
L
S
S
S
E
M
E
E
F
L
Site 35
S1498
D
L
P
P
L
S
S
S
E
M
E
E
F
L
T
Site 36
T1505
S
E
M
E
E
F
L
T
Q
E
S
K
K
H
E
Site 37
Y1527
A
L
T
E
I
Y
K
Y
I
V
K
Y
F
D
E
Site 38
Y1531
I
Y
K
Y
I
V
K
Y
F
D
E
I
L
N
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation