PhosphoNET

           
Protein Info 
   
Short Name:  4E-BP3
Full Name:  Eukaryotic translation initiation factor 4E-binding protein 3
Alias:  4EBP3; EIF4E-binding protein 3; EIF4E-binding protein 3;; EIF4EBP3; Eukaryotic translation initiation factor 4E binding protein 3
Type:  Translation
Mass (Da):  10873
Number AA:  100
UniProt ID:  O60516
International Prot ID:  IPI00021476
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016281     Uniprot OncoNet
Molecular Function:  GO:0008190  GO:0030371   PhosphoSite+ KinaseNET
Biological Process:  GO:0045947     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MSTSTSCPIPGGR
Site 2Y20RDQLPDCYSTTPGGT
Site 3S21DQLPDCYSTTPGGTL
Site 4T22QLPDCYSTTPGGTLY
Site 5T23LPDCYSTTPGGTLYA
Site 6T27YSTTPGGTLYATTPG
Site 7Y29TTPGGTLYATTPGGT
Site 8T31PGGTLYATTPGGTRI
Site 9T32GGTLYATTPGGTRII
Site 10T36YATTPGGTRIIYDRK
Site 11Y40PGGTRIIYDRKFLLE
Site 12S51FLLECKNSPIARTPP
Site 13T56KNSPIARTPPCCLPQ
Site 14T69PQIPGVTTPPTAPLS
Site 15T72PGVTTPPTAPLSKLE
Site 16S76TPPTAPLSKLEELKE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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