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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NMT2
Full Name:
Glycylpeptide N-tetradecanoyltransferase 2
Alias:
EC 2.3.1.97; Myristoyl-CoA:protein N-myristoyltransferase 2; Myristoyl-CoA;protein N-myristoyltransferase 2; NMT 2; N-myristoyltransferase 2; Peptide N-myristoyltransferase 2; Type II N-myristoyltransferase
Type:
Enzyme - Myristoyltransferase
Mass (Da):
56980
Number AA:
498
UniProt ID:
O60551
International Prot ID:
IPI00030223
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
Uniprot
OncoNet
Molecular Function:
GO:0004379
PhosphoSite+
KinaseNET
Biological Process:
GO:0006499
GO:0009249
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
E
D
S
E
S
A
A
S
Q
Q
S
L
Site 2
S10
E
D
S
E
S
A
A
S
Q
Q
S
L
E
L
D
Site 3
T21
L
E
L
D
D
Q
D
T
C
G
I
D
G
D
N
Site 4
T32
D
G
D
N
E
E
E
T
E
H
A
K
G
S
P
Site 5
S38
E
T
E
H
A
K
G
S
P
G
G
Y
L
G
A
Site 6
Y42
A
K
G
S
P
G
G
Y
L
G
A
K
K
K
K
Site 7
S61
R
K
K
E
K
P
N
S
G
G
T
K
S
D
S
Site 8
T64
E
K
P
N
S
G
G
T
K
S
D
S
A
S
D
Site 9
S66
P
N
S
G
G
T
K
S
D
S
A
S
D
S
Q
Site 10
S68
S
G
G
T
K
S
D
S
A
S
D
S
Q
E
I
Site 11
S70
G
T
K
S
D
S
A
S
D
S
Q
E
I
K
I
Site 12
S72
K
S
D
S
A
S
D
S
Q
E
I
K
I
Q
Q
Site 13
S81
E
I
K
I
Q
Q
P
S
K
N
P
S
V
P
M
Site 14
S85
Q
Q
P
S
K
N
P
S
V
P
M
Q
K
L
Q
Site 15
S102
Q
R
A
M
E
L
L
S
A
C
Q
G
P
A
R
Site 16
T124
H
R
Y
Q
F
W
D
T
Q
P
V
P
K
L
D
Site 17
S136
K
L
D
E
V
I
T
S
H
G
A
I
E
P
D
Site 18
Y152
D
N
V
R
Q
E
P
Y
S
L
P
Q
G
F
M
Site 19
T162
P
Q
G
F
M
W
D
T
L
D
L
S
D
A
E
Site 20
S166
M
W
D
T
L
D
L
S
D
A
E
V
L
K
E
Site 21
T176
E
V
L
K
E
L
Y
T
L
L
N
E
N
Y
V
Site 22
Y182
Y
T
L
L
N
E
N
Y
V
E
D
D
D
N
M
Site 23
Y194
D
N
M
F
R
F
D
Y
S
P
E
F
L
L
W
Site 24
S220
H
C
G
V
R
V
S
S
N
K
K
L
V
G
F
Site 25
S229
K
K
L
V
G
F
I
S
A
I
P
A
N
I
R
Site 26
S258
C
V
H
K
K
L
R
S
K
R
V
A
P
V
L
Site 27
T270
P
V
L
I
R
E
I
T
R
R
V
N
L
E
G
Site 28
Y283
E
G
I
F
Q
A
V
Y
T
A
G
V
V
L
P
Site 29
T295
V
L
P
K
P
I
A
T
C
R
Y
W
H
R
S
Site 30
Y298
K
P
I
A
T
C
R
Y
W
H
R
S
L
N
P
Site 31
T321
S
H
L
S
R
N
M
T
L
Q
R
T
M
K
L
Site 32
Y329
L
Q
R
T
M
K
L
Y
R
L
P
D
V
T
K
Site 33
T335
L
Y
R
L
P
D
V
T
K
T
S
G
L
R
P
Site 34
S338
L
P
D
V
T
K
T
S
G
L
R
P
M
E
P
Site 35
S350
M
E
P
K
D
I
K
S
V
R
E
L
I
N
T
Site 36
T357
S
V
R
E
L
I
N
T
Y
L
K
Q
F
H
L
Site 37
T386
P
R
E
H
I
I
D
T
F
V
V
E
S
P
N
Site 38
S391
I
D
T
F
V
V
E
S
P
N
G
K
L
T
D
Site 39
T397
E
S
P
N
G
K
L
T
D
F
L
S
F
Y
T
Site 40
T408
S
F
Y
T
L
P
S
T
V
M
H
H
P
A
H
Site 41
S423
K
S
L
K
A
A
Y
S
F
Y
N
I
H
T
E
Site 42
T462
L
D
L
M
E
N
K
T
F
L
E
K
L
K
F
Site 43
Y478
I
G
D
G
N
L
Q
Y
Y
L
Y
N
W
R
C
Site 44
Y479
G
D
G
N
L
Q
Y
Y
L
Y
N
W
R
C
P
Site 45
Y481
G
N
L
Q
Y
Y
L
Y
N
W
R
C
P
G
T
Site 46
T488
Y
N
W
R
C
P
G
T
D
S
E
K
V
G
L
Site 47
S490
W
R
C
P
G
T
D
S
E
K
V
G
L
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation