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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLOD3
Full Name:
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Alias:
Lysyl hydroxylase 3
Type:
Mass (Da):
84767
Number AA:
738
UniProt ID:
O60568
International Prot ID:
IPI00030255
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005789
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0005506
PhosphoSite+
KinaseNET
Biological Process:
GO:0006464
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
L
L
L
P
P
A
A
S
A
S
D
R
P
R
G
Site 2
S25
L
P
P
A
A
S
A
S
D
R
P
R
G
R
D
Site 3
Y52
A
T
A
E
T
E
G
Y
L
R
F
L
R
S
A
Site 4
S58
G
Y
L
R
F
L
R
S
A
E
F
F
N
Y
T
Site 5
Y64
R
S
A
E
F
F
N
Y
T
V
R
T
L
G
L
Site 6
T83
R
G
G
D
V
A
R
T
V
G
G
G
Q
K
V
Site 7
Y100
L
K
K
E
M
E
K
Y
A
D
R
E
D
M
I
Site 8
S134
K
K
F
V
Q
S
G
S
R
L
L
F
S
A
E
Site 9
S139
S
G
S
R
L
L
F
S
A
E
S
F
C
W
P
Site 10
Y154
E
W
G
L
A
E
Q
Y
P
E
V
G
T
G
K
Site 11
Y195
D
D
D
D
Q
L
F
Y
T
R
L
Y
L
D
P
Site 12
Y199
Q
L
F
Y
T
R
L
Y
L
D
P
G
L
R
E
Site 13
S209
P
G
L
R
E
K
L
S
L
N
L
D
H
K
S
Site 14
S216
S
L
N
L
D
H
K
S
R
I
F
Q
N
L
N
Site 15
Y268
Q
L
N
Y
L
G
N
Y
V
P
N
G
W
T
P
Site 16
T288
F
C
N
Q
D
R
R
T
L
P
G
G
Q
P
P
Site 17
Y323
Q
R
L
L
L
L
D
Y
P
P
D
R
V
T
L
Site 18
T329
D
Y
P
P
D
R
V
T
L
F
L
H
N
N
E
Site 19
S355
P
Q
L
Q
D
H
F
S
A
V
K
L
V
G
P
Site 20
S367
V
G
P
E
E
A
L
S
P
G
E
A
R
D
M
Site 21
Y388
Q
D
P
E
C
E
F
Y
F
S
L
D
A
D
A
Site 22
S419
K
V
I
A
P
M
L
S
R
H
G
K
L
W
S
Site 23
S433
S
N
F
W
G
A
L
S
P
D
E
Y
Y
A
R
Site 24
Y437
G
A
L
S
P
D
E
Y
Y
A
R
S
E
D
Y
Site 25
Y438
A
L
S
P
D
E
Y
Y
A
R
S
E
D
Y
V
Site 26
Y444
Y
Y
A
R
S
E
D
Y
V
E
L
V
Q
R
K
Site 27
Y460
V
G
V
W
N
V
P
Y
I
S
Q
A
Y
V
I
Site 28
T471
A
Y
V
I
R
G
D
T
L
R
M
E
L
P
Q
Site 29
S483
L
P
Q
R
D
V
F
S
G
S
D
T
D
P
D
Site 30
S485
Q
R
D
V
F
S
G
S
D
T
D
P
D
M
A
Site 31
T487
D
V
F
S
G
S
D
T
D
P
D
M
A
F
C
Site 32
S507
K
G
I
F
L
H
L
S
N
Q
H
E
F
G
R
Site 33
T518
E
F
G
R
L
L
A
T
S
R
Y
D
T
E
H
Site 34
S519
F
G
R
L
L
A
T
S
R
Y
D
T
E
H
L
Site 35
Y521
R
L
L
A
T
S
R
Y
D
T
E
H
L
H
P
Site 36
T523
L
A
T
S
R
Y
D
T
E
H
L
H
P
D
L
Site 37
Y544
P
V
D
W
K
E
Q
Y
I
H
E
N
Y
S
R
Site 38
Y549
E
Q
Y
I
H
E
N
Y
S
R
A
L
E
G
E
Site 39
Y567
E
Q
P
C
P
D
V
Y
W
F
P
L
L
S
E
Site 40
Y587
L
V
A
E
M
E
H
Y
G
Q
W
S
G
G
R
Site 41
S598
S
G
G
R
H
E
D
S
R
L
A
G
G
Y
E
Site 42
Y604
D
S
R
L
A
G
G
Y
E
N
V
P
T
V
D
Site 43
T609
G
G
Y
E
N
V
P
T
V
D
I
H
M
K
Q
Site 44
T629
Q
W
L
Q
L
L
R
T
Y
V
G
P
M
T
E
Site 45
Y630
W
L
Q
L
L
R
T
Y
V
G
P
M
T
E
S
Site 46
T635
R
T
Y
V
G
P
M
T
E
S
L
F
P
G
Y
Site 47
Y642
T
E
S
L
F
P
G
Y
H
T
K
A
R
A
V
Site 48
S663
Y
R
P
D
E
Q
P
S
L
R
P
H
H
D
S
Site 49
S670
S
L
R
P
H
H
D
S
S
T
F
T
L
N
V
Site 50
T672
R
P
H
H
D
S
S
T
F
T
L
N
V
A
L
Site 51
T674
H
H
D
S
S
T
F
T
L
N
V
A
L
N
H
Site 52
Y686
L
N
H
K
G
L
D
Y
E
G
G
G
C
R
F
Site 53
S701
L
R
Y
D
C
V
I
S
S
P
R
K
G
W
A
Site 54
S702
R
Y
D
C
V
I
S
S
P
R
K
G
W
A
L
Site 55
T716
L
L
H
P
G
R
L
T
H
Y
H
E
G
L
P
Site 56
Y718
H
P
G
R
L
T
H
Y
H
E
G
L
P
T
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation