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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEC6L1
Full Name:
Exocyst complex component 3
Alias:
EXOC3; Exocyst complex component Sec6; Exocyst complex component SEC6; SEC6-like 1 (S. cerevisiae); Sec6p
Type:
Vesicle protein
Mass (Da):
86845
Number AA:
756
UniProt ID:
O60645
International Prot ID:
IPI00157734
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006887
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
T
D
R
E
A
V
A
T
A
V
Q
R
V
A
G
Site 2
Y43
Q
L
D
K
V
E
Q
Y
R
R
R
E
A
R
K
Site 3
S53
R
E
A
R
K
K
A
S
V
E
A
R
L
K
A
Site 4
T71
S
Q
L
D
G
V
R
T
G
L
S
Q
L
H
N
Site 5
S74
D
G
V
R
T
G
L
S
Q
L
H
N
A
L
N
Site 6
S89
D
V
K
D
I
Q
Q
S
L
A
D
V
S
K
D
Site 7
S100
V
S
K
D
W
R
Q
S
I
N
T
I
E
S
L
Site 8
T103
D
W
R
Q
S
I
N
T
I
E
S
L
K
D
V
Site 9
S106
Q
S
I
N
T
I
E
S
L
K
D
V
K
D
A
Site 10
S132
E
N
L
K
N
I
F
S
V
P
E
I
V
R
E
Site 11
T140
V
P
E
I
V
R
E
T
Q
D
L
I
E
Q
G
Site 12
Y168
C
S
R
D
G
L
M
Y
E
Q
Y
R
M
D
S
Site 13
Y171
D
G
L
M
Y
E
Q
Y
R
M
D
S
G
N
T
Site 14
T182
S
G
N
T
R
D
M
T
L
I
H
G
Y
F
G
Site 15
S190
L
I
H
G
Y
F
G
S
T
Q
G
L
S
D
E
Site 16
S195
F
G
S
T
Q
G
L
S
D
E
L
A
K
Q
L
Site 17
S209
L
W
M
V
L
Q
R
S
L
V
T
V
R
R
D
Site 18
T212
V
L
Q
R
S
L
V
T
V
R
R
D
P
T
L
Site 19
T261
N
W
K
E
K
M
F
T
I
L
E
R
T
V
T
Site 20
T268
T
I
L
E
R
T
V
T
T
R
I
E
G
T
Q
Site 21
S281
T
Q
A
D
T
R
E
S
D
K
M
W
L
V
R
Site 22
Y326
F
K
N
L
L
N
M
Y
H
Q
A
L
S
T
R
Site 23
Y358
L
T
W
V
L
N
T
Y
T
S
T
E
M
M
R
Site 24
Y394
V
S
E
L
L
D
T
Y
M
S
T
L
T
S
N
Site 25
T412
W
L
R
K
A
L
E
T
D
K
K
D
W
V
K
Site 26
Y430
P
E
A
D
Q
D
G
Y
Y
Q
T
T
L
P
A
Site 27
Y431
E
A
D
Q
D
G
Y
Y
Q
T
T
L
P
A
I
Site 28
S471
L
C
L
Q
Q
M
N
S
F
L
S
R
Y
K
D
Site 29
Y483
Y
K
D
E
A
Q
L
Y
K
E
E
H
L
R
N
Site 30
S517
T
F
K
E
S
I
V
S
L
K
R
K
Y
L
K
Site 31
Y522
I
V
S
L
K
R
K
Y
L
K
N
E
V
E
E
Site 32
S532
N
E
V
E
E
G
V
S
P
S
Q
P
S
M
D
Site 33
S534
V
E
E
G
V
S
P
S
Q
P
S
M
D
G
I
Site 34
S537
G
V
S
P
S
Q
P
S
M
D
G
I
L
D
A
Site 35
T606
K
P
Y
K
K
R
M
T
A
E
A
H
R
R
V
Site 36
Y617
H
R
R
V
V
V
E
Y
L
R
A
V
M
Q
K
Site 37
S627
A
V
M
Q
K
R
I
S
F
R
S
P
E
E
R
Site 38
S630
Q
K
R
I
S
F
R
S
P
E
E
R
K
E
G
Site 39
S694
L
E
V
S
T
L
V
S
K
Y
P
D
I
R
D
Site 40
Y696
V
S
T
L
V
S
K
Y
P
D
I
R
D
D
H
Site 41
T721
A
S
R
D
M
K
Q
T
I
M
E
T
L
E
Q
Site 42
S734
E
Q
G
P
A
Q
A
S
P
S
Y
V
P
L
F
Site 43
S736
G
P
A
Q
A
S
P
S
Y
V
P
L
F
K
D
Site 44
Y737
P
A
Q
A
S
P
S
Y
V
P
L
F
K
D
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation