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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
M6PRBP1
Full Name:
Perilipin-3
Alias:
47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; Cargo selection protein (mannose 6 phosphate receptor binding protein); Cargo selection protein TIP47; M6PBP; Mannose 6 phosphate receptor binding protein 1; Mannose-6-phosphate receptor binding protein 1; MGC11117; MGC2012; MPR-binding protein 47 kDa; MPR-BINDING PROTEIN, 47-KD; Perilipin 3; Placental protein 17; PP17; TIP47
Type:
Vesicle protein
Mass (Da):
47047
Number AA:
434
UniProt ID:
O60664
International Prot ID:
IPI00106668
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005768
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
A
D
G
A
E
A
D
Site 2
S11
D
G
A
E
A
D
G
S
T
Q
V
T
V
E
E
Site 3
T12
G
A
E
A
D
G
S
T
Q
V
T
V
E
E
P
Site 4
T15
A
D
G
S
T
Q
V
T
V
E
E
P
V
Q
Q
Site 5
S24
E
E
P
V
Q
Q
P
S
V
V
D
R
V
A
S
Site 6
S31
S
V
V
D
R
V
A
S
M
P
L
I
S
S
T
Site 7
S37
A
S
M
P
L
I
S
S
T
C
D
M
V
S
A
Site 8
S43
S
S
T
C
D
M
V
S
A
A
Y
A
S
T
K
Site 9
Y46
C
D
M
V
S
A
A
Y
A
S
T
K
E
S
Y
Site 10
S48
M
V
S
A
A
Y
A
S
T
K
E
S
Y
P
H
Site 11
S52
A
Y
A
S
T
K
E
S
Y
P
H
I
K
T
V
Site 12
Y53
Y
A
S
T
K
E
S
Y
P
H
I
K
T
V
C
Site 13
T58
E
S
Y
P
H
I
K
T
V
C
D
A
A
E
K
Site 14
S83
S
G
A
Q
P
I
L
S
K
L
E
P
Q
I
A
Site 15
S91
K
L
E
P
Q
I
A
S
A
S
E
Y
A
H
R
Site 16
S93
E
P
Q
I
A
S
A
S
E
Y
A
H
R
G
L
Site 17
Y95
Q
I
A
S
A
S
E
Y
A
H
R
G
L
D
K
Site 18
T121
T
E
K
V
L
A
D
T
K
E
L
V
S
S
K
Site 19
S126
A
D
T
K
E
L
V
S
S
K
V
S
G
A
Q
Site 20
S127
D
T
K
E
L
V
S
S
K
V
S
G
A
Q
E
Site 21
S130
E
L
V
S
S
K
V
S
G
A
Q
E
M
V
S
Site 22
S137
S
G
A
Q
E
M
V
S
S
A
K
D
T
V
A
Site 23
T142
M
V
S
S
A
K
D
T
V
A
T
Q
L
S
E
Site 24
S148
D
T
V
A
T
Q
L
S
E
A
V
D
A
T
R
Site 25
T154
L
S
E
A
V
D
A
T
R
G
A
V
Q
S
G
Site 26
S160
A
T
R
G
A
V
Q
S
G
V
D
K
T
K
S
Site 27
T165
V
Q
S
G
V
D
K
T
K
S
V
V
T
G
G
Site 28
S167
S
G
V
D
K
T
K
S
V
V
T
G
G
V
Q
Site 29
T170
D
K
T
K
S
V
V
T
G
G
V
Q
S
V
M
Site 30
S175
V
V
T
G
G
V
Q
S
V
M
G
S
R
L
G
Site 31
S179
G
V
Q
S
V
M
G
S
R
L
G
Q
M
V
L
Site 32
S187
R
L
G
Q
M
V
L
S
G
V
D
T
V
L
G
Site 33
S196
V
D
T
V
L
G
K
S
E
E
W
A
D
N
H
Site 34
T207
A
D
N
H
L
P
L
T
D
A
E
L
A
R
I
Site 35
T216
A
E
L
A
R
I
A
T
S
L
D
G
F
D
V
Site 36
S225
L
D
G
F
D
V
A
S
V
Q
Q
Q
R
Q
E
Site 37
Y235
Q
Q
R
Q
E
Q
S
Y
F
V
R
L
G
S
L
Site 38
S241
S
Y
F
V
R
L
G
S
L
S
E
R
L
R
Q
Site 39
S243
F
V
R
L
G
S
L
S
E
R
L
R
Q
H
A
Site 40
Y251
E
R
L
R
Q
H
A
Y
E
H
S
L
G
K
L
Site 41
S254
R
Q
H
A
Y
E
H
S
L
G
K
L
R
A
T
Site 42
T261
S
L
G
K
L
R
A
T
K
Q
R
A
Q
E
A
Site 43
T281
Q
A
L
S
L
M
E
T
V
K
Q
G
V
D
Q
Site 44
S324
P
K
P
E
Q
V
E
S
R
A
L
T
M
F
R
Site 45
T328
Q
V
E
S
R
A
L
T
M
F
R
D
I
A
Q
Site 46
T342
Q
Q
L
Q
A
T
C
T
S
L
G
S
S
I
Q
Site 47
S343
Q
L
Q
A
T
C
T
S
L
G
S
S
I
Q
G
Site 48
S347
T
C
T
S
L
G
S
S
I
Q
G
L
P
T
N
Site 49
T372
Q
V
E
D
L
Q
A
T
F
S
S
I
H
S
F
Site 50
S374
E
D
L
Q
A
T
F
S
S
I
H
S
F
Q
D
Site 51
S378
A
T
F
S
S
I
H
S
F
Q
D
L
S
S
S
Site 52
S383
I
H
S
F
Q
D
L
S
S
S
I
L
A
Q
S
Site 53
S384
H
S
F
Q
D
L
S
S
S
I
L
A
Q
S
R
Site 54
S385
S
F
Q
D
L
S
S
S
I
L
A
Q
S
R
E
Site 55
S390
S
S
S
I
L
A
Q
S
R
E
R
V
A
S
A
Site 56
S396
Q
S
R
E
R
V
A
S
A
R
E
A
L
D
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation