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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCC9
Full Name:
ATP-binding cassette sub-family C member 9
Alias:
ABC37; ATP-binding cassette, sub-family C (CFTR/MRP) member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; CMD1O; Sulfonylurea receptor 2; Sulfonylurea receptor 2A; SUR2
Type:
Transporter; Channel, potassium
Mass (Da):
174205
Number AA:
1549
UniProt ID:
O60706
International Prot ID:
IPI00024278
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008282
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042626
GO:0015459
PhosphoSite+
KinaseNET
Biological Process:
GO:0051607
GO:0010107
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
C
G
N
N
I
S
S
Y
N
I
N
D
G
V
L
Site 2
S53
F
I
G
W
G
S
Q
S
S
K
V
Q
I
H
H
Site 3
S93
E
I
A
E
G
I
V
S
D
S
R
R
E
S
R
Site 4
S95
A
E
G
I
V
S
D
S
R
R
E
S
R
H
L
Site 5
S99
V
S
D
S
R
R
E
S
R
H
L
H
L
F
M
Site 6
Y122
T
T
T
S
I
V
Y
Y
H
N
I
E
T
S
N
Site 7
Y193
N
V
I
R
V
R
R
Y
V
F
F
M
N
P
Q
Site 8
Y268
Y
V
C
L
K
D
A
Y
E
E
Q
K
K
K
V
Site 9
T282
V
A
D
H
P
N
R
T
P
S
I
W
L
A
M
Site 10
S284
D
H
P
N
R
T
P
S
I
W
L
A
M
Y
R
Site 11
S339
T
N
N
T
T
G
I
S
E
T
L
S
S
K
E
Site 12
T341
N
T
T
G
I
S
E
T
L
S
S
K
E
F
L
Site 13
S343
T
G
I
S
E
T
L
S
S
K
E
F
L
E
N
Site 14
S344
G
I
S
E
T
L
S
S
K
E
F
L
E
N
A
Site 15
S372
Q
R
T
F
L
Q
A
S
Y
Y
V
T
I
E
T
Site 16
S399
Y
N
K
I
L
R
L
S
T
S
N
L
S
M
G
Site 17
T400
N
K
I
L
R
L
S
T
S
N
L
S
M
G
E
Site 18
S401
K
I
L
R
L
S
T
S
N
L
S
M
G
E
M
Site 19
S404
R
L
S
T
S
N
L
S
M
G
E
M
T
L
G
Site 20
S483
K
L
A
E
A
Q
K
S
T
L
D
Y
S
T
E
Site 21
T484
L
A
E
A
Q
K
S
T
L
D
Y
S
T
E
R
Site 22
Y487
A
Q
K
S
T
L
D
Y
S
T
E
R
L
K
K
Site 23
S488
Q
K
S
T
L
D
Y
S
T
E
R
L
K
K
T
Site 24
T489
K
S
T
L
D
Y
S
T
E
R
L
K
K
T
N
Site 25
T495
S
T
E
R
L
K
K
T
N
E
I
L
K
G
I
Site 26
T521
F
C
K
S
V
E
E
T
R
M
K
E
L
S
S
Site 27
S527
E
T
R
M
K
E
L
S
S
L
K
T
F
A
L
Site 28
S528
T
R
M
K
E
L
S
S
L
K
T
F
A
L
Y
Site 29
S611
K
L
N
E
F
L
L
S
D
E
I
G
D
D
S
Site 30
S618
S
D
E
I
G
D
D
S
W
R
T
G
E
S
S
Site 31
T621
I
G
D
D
S
W
R
T
G
E
S
S
L
P
F
Site 32
S624
D
S
W
R
T
G
E
S
S
L
P
F
E
S
C
Site 33
S625
S
W
R
T
G
E
S
S
L
P
F
E
S
C
K
Site 34
S630
E
S
S
L
P
F
E
S
C
K
K
H
T
G
V
Site 35
T635
F
E
S
C
K
K
H
T
G
V
Q
P
K
T
I
Site 36
T641
H
T
G
V
Q
P
K
T
I
N
R
K
Q
P
G
Site 37
S654
P
G
R
Y
H
L
D
S
Y
E
Q
S
T
R
R
Site 38
Y655
G
R
Y
H
L
D
S
Y
E
Q
S
T
R
R
L
Site 39
S658
H
L
D
S
Y
E
Q
S
T
R
R
L
R
P
A
Site 40
S683
N
G
Y
F
S
W
G
S
G
L
A
T
L
S
N
Site 41
T687
S
W
G
S
G
L
A
T
L
S
N
I
D
I
R
Site 42
T724
A
I
L
G
E
M
Q
T
L
E
G
K
V
H
W
Site 43
S732
L
E
G
K
V
H
W
S
N
V
N
E
S
E
P
Site 44
S740
N
V
N
E
S
E
P
S
F
E
A
T
R
S
R
Site 45
T744
S
E
P
S
F
E
A
T
R
S
R
N
R
Y
S
Site 46
S746
P
S
F
E
A
T
R
S
R
N
R
Y
S
V
A
Site 47
Y750
A
T
R
S
R
N
R
Y
S
V
A
Y
A
A
Q
Site 48
S751
T
R
S
R
N
R
Y
S
V
A
Y
A
A
Q
K
Site 49
Y754
R
N
R
Y
S
V
A
Y
A
A
Q
K
P
W
L
Site 50
T765
K
P
W
L
L
N
A
T
V
E
E
N
I
T
F
Site 51
T771
A
T
V
E
E
N
I
T
F
G
S
P
F
N
K
Site 52
S774
E
E
N
I
T
F
G
S
P
F
N
K
Q
R
Y
Site 53
Y781
S
P
F
N
K
Q
R
Y
K
A
V
T
D
A
C
Site 54
T785
K
Q
R
Y
K
A
V
T
D
A
C
S
L
Q
P
Site 55
T803
L
L
P
F
G
D
Q
T
E
I
G
E
R
G
I
Site 56
S813
G
E
R
G
I
N
L
S
G
G
Q
R
Q
R
I
Site 57
S847
S
A
L
D
I
H
L
S
D
H
L
M
Q
E
G
Site 58
T865
F
L
Q
D
D
K
R
T
L
V
L
V
T
H
K
Site 59
T895
G
S
V
L
R
E
G
T
L
K
D
I
Q
T
K
Site 60
T901
G
T
L
K
D
I
Q
T
K
D
V
E
L
Y
E
Site 61
Y907
Q
T
K
D
V
E
L
Y
E
H
W
K
T
L
M
Site 62
T930
K
D
M
E
A
D
Q
T
T
L
E
R
K
T
L
Site 63
T931
D
M
E
A
D
Q
T
T
L
E
R
K
T
L
R
Site 64
T936
Q
T
T
L
E
R
K
T
L
R
R
A
M
Y
S
Site 65
Y942
K
T
L
R
R
A
M
Y
S
R
E
A
K
A
Q
Site 66
S943
T
L
R
R
A
M
Y
S
R
E
A
K
A
Q
M
Site 67
S968
E
D
E
D
D
N
M
S
T
V
M
R
L
R
T
Site 68
T975
S
T
V
M
R
L
R
T
K
M
P
W
K
T
C
Site 69
T1017
A
I
D
Y
W
L
A
T
W
T
S
E
Y
S
I
Site 70
T1033
N
T
G
K
A
D
Q
T
Y
Y
V
A
G
F
S
Site 71
Y1034
T
G
K
A
D
Q
T
Y
Y
V
A
G
F
S
I
Site 72
T1063
T
V
E
W
M
G
L
T
A
A
K
N
L
H
H
Site 73
T1110
I
D
Q
H
I
P
P
T
L
E
S
L
T
R
S
Site 74
S1113
H
I
P
P
T
L
E
S
L
T
R
S
T
L
L
Site 75
Y1152
A
F
Y
F
I
Q
K
Y
F
R
V
A
S
K
D
Site 76
S1157
Q
K
Y
F
R
V
A
S
K
D
L
Q
E
L
D
Site 77
S1166
D
L
Q
E
L
D
D
S
T
Q
L
P
L
L
C
Site 78
T1167
L
Q
E
L
D
D
S
T
Q
L
P
L
L
C
H
Site 79
T1184
E
T
A
E
G
L
T
T
I
R
A
F
R
H
E
Site 80
T1192
I
R
A
F
R
H
E
T
R
F
K
Q
R
M
L
Site 81
T1202
K
Q
R
M
L
E
L
T
D
T
N
N
I
A
Y
Site 82
S1284
G
A
V
K
K
V
N
S
F
L
T
M
E
S
E
Site 83
Y1293
L
T
M
E
S
E
N
Y
E
G
T
M
D
P
S
Site 84
T1296
E
S
E
N
Y
E
G
T
M
D
P
S
Q
V
P
Site 85
Y1335
V
L
K
H
V
K
A
Y
I
K
P
G
Q
K
V
Site 86
T1348
K
V
G
I
C
G
R
T
G
S
G
K
S
S
L
Site 87
S1350
G
I
C
G
R
T
G
S
G
K
S
S
L
S
L
Site 88
S1353
G
R
T
G
S
G
K
S
S
L
S
L
A
F
F
Site 89
S1354
R
T
G
S
G
K
S
S
L
S
L
A
F
F
R
Site 90
S1378
V
I
D
G
I
D
I
S
K
L
P
L
H
T
L
Site 91
S1390
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
I
Site 92
S1402
D
P
I
L
F
S
G
S
I
R
F
N
L
D
P
Site 93
T1414
L
D
P
E
C
K
C
T
D
D
R
L
W
E
A
Site 94
S1433
Q
L
K
N
M
V
K
S
L
P
G
G
L
D
A
Site 95
T1443
G
G
L
D
A
V
V
T
E
G
G
E
N
F
S
Site 96
S1450
T
E
G
G
E
N
F
S
V
G
Q
R
Q
L
F
Site 97
S1468
R
A
F
V
R
K
S
S
I
L
I
M
D
E
A
Site 98
S1478
I
M
D
E
A
T
A
S
I
D
M
A
T
E
N
Site 99
T1543
H
K
N
G
L
F
S
T
L
V
M
T
N
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation