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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Leupaxin
Full Name:
Leupaxin
Alias:
AV278559; LDLP; LDPL; LPAX; LPXN
Type:
Cytoskeletal protein, adapter/scaffold protein
Mass (Da):
43332
Number AA:
386
UniProt ID:
O60711
International Prot ID:
IPI00299066
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0006461
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
L
L
E
E
L
E
R
S
T
L
Q
D
S
D
E
Site 2
T15
L
E
E
L
E
R
S
T
L
Q
D
S
D
E
Y
Site 3
S19
E
R
S
T
L
Q
D
S
D
E
Y
S
N
P
A
Site 4
Y22
T
L
Q
D
S
D
E
Y
S
N
P
A
P
L
P
Site 5
S23
L
Q
D
S
D
E
Y
S
N
P
A
P
L
P
L
Site 6
T38
D
Q
H
S
R
K
E
T
N
L
D
E
T
S
E
Site 7
T43
K
E
T
N
L
D
E
T
S
E
I
L
S
I
Q
Site 8
S44
E
T
N
L
D
E
T
S
E
I
L
S
I
Q
D
Site 9
S48
D
E
T
S
E
I
L
S
I
Q
D
N
T
S
P
Site 10
S54
L
S
I
Q
D
N
T
S
P
L
P
A
Q
L
V
Site 11
Y62
P
L
P
A
Q
L
V
Y
T
T
N
I
Q
E
L
Site 12
Y72
N
I
Q
E
L
N
V
Y
S
E
A
Q
E
P
K
Site 13
S81
E
A
Q
E
P
K
E
S
P
P
P
S
K
T
S
Site 14
S85
P
K
E
S
P
P
P
S
K
T
S
A
A
A
Q
Site 15
S88
S
P
P
P
S
K
T
S
A
A
A
Q
L
D
E
Site 16
S127
D
K
Q
D
H
K
A
S
L
D
S
M
L
G
G
Site 17
S130
D
H
K
A
S
L
D
S
M
L
G
G
L
E
Q
Site 18
S154
V
P
K
G
H
C
A
S
C
Q
K
P
I
A
G
Site 19
S187
H
C
K
E
E
I
G
S
S
P
F
F
E
R
S
Site 20
S188
C
K
E
E
I
G
S
S
P
F
F
E
R
S
G
Site 21
Y198
F
E
R
S
G
L
A
Y
C
P
N
D
Y
H
Q
Site 22
Y203
L
A
Y
C
P
N
D
Y
H
Q
L
F
S
P
R
Site 23
Y213
L
F
S
P
R
C
A
Y
C
A
A
P
I
L
D
Site 24
S267
K
D
F
L
A
M
F
S
P
K
C
G
G
C
N
Site 25
Y281
N
R
P
V
L
E
N
Y
L
S
A
M
D
T
V
Site 26
S307
F
T
S
F
S
T
G
S
F
F
E
L
D
G
R
Site 27
Y321
R
P
F
C
E
L
H
Y
H
H
R
R
G
T
L
Site 28
S363
A
F
C
L
T
Q
L
S
K
G
I
F
R
E
Q
Site 29
Y375
R
E
Q
N
D
K
T
Y
C
Q
P
C
F
N
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation