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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDC14B
Full Name:
Dual specificity protein phosphatase CDC14B
Alias:
CDC14 cell division cycle 14 homolog B
Type:
Mass (Da):
56802
Number AA:
498
UniProt ID:
O60729
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
K
R
K
S
E
R
R
S
S
W
A
A
A
P
P
Site 2
S10
R
K
S
E
R
R
S
S
W
A
A
A
P
P
C
Site 3
S18
W
A
A
A
P
P
C
S
R
R
C
S
S
T
S
Site 4
S22
P
P
C
S
R
R
C
S
S
T
S
P
G
V
K
Site 5
S23
P
C
S
R
R
C
S
S
T
S
P
G
V
K
K
Site 6
T24
C
S
R
R
C
S
S
T
S
P
G
V
K
K
I
Site 7
S25
S
R
R
C
S
S
T
S
P
G
V
K
K
I
R
Site 8
S33
P
G
V
K
K
I
R
S
S
T
Q
Q
D
P
R
Site 9
S34
G
V
K
K
I
R
S
S
T
Q
Q
D
P
R
R
Site 10
T35
V
K
K
I
R
S
S
T
Q
Q
D
P
R
R
R
Site 11
Y49
R
D
P
Q
D
D
V
Y
L
D
I
T
D
R
L
Site 12
Y62
R
L
C
F
A
I
L
Y
S
R
P
K
S
A
S
Site 13
S67
I
L
Y
S
R
P
K
S
A
S
N
V
H
Y
F
Site 14
S69
Y
S
R
P
K
S
A
S
N
V
H
Y
F
S
I
Site 15
Y73
K
S
A
S
N
V
H
Y
F
S
I
D
N
E
L
Site 16
S75
A
S
N
V
H
Y
F
S
I
D
N
E
L
E
Y
Site 17
Y82
S
I
D
N
E
L
E
Y
E
N
F
Y
A
D
F
Site 18
Y86
E
L
E
Y
E
N
F
Y
A
D
F
G
P
L
N
Site 19
Y100
N
L
A
M
V
Y
R
Y
C
C
K
I
N
K
K
Site 20
S110
K
I
N
K
K
L
K
S
I
T
M
L
R
K
K
Site 21
S124
K
I
V
H
F
T
G
S
D
Q
R
K
Q
A
N
Site 22
T147
M
V
I
Y
L
G
R
T
P
E
E
A
Y
R
I
Site 23
T160
R
I
L
I
F
G
E
T
S
Y
I
P
F
R
D
Site 24
Y205
N
S
F
N
L
D
E
Y
E
H
Y
E
K
A
E
Site 25
Y208
N
L
D
E
Y
E
H
Y
E
K
A
E
N
G
D
Site 26
S232
I
A
F
C
G
P
H
S
R
A
R
L
E
S
G
Site 27
S238
H
S
R
A
R
L
E
S
G
Y
H
Q
H
S
P
Site 28
Y240
R
A
R
L
E
S
G
Y
H
Q
H
S
P
E
T
Site 29
S244
E
S
G
Y
H
Q
H
S
P
E
T
Y
I
Q
Y
Site 30
Y248
H
Q
H
S
P
E
T
Y
I
Q
Y
F
K
N
H
Site 31
Y251
S
P
E
T
Y
I
Q
Y
F
K
N
H
N
V
T
Site 32
Y268
I
R
L
N
K
R
M
Y
D
A
K
R
F
T
D
Site 33
S351
V
R
I
C
R
P
G
S
V
I
G
P
Q
Q
Q
Site 34
Y373
N
L
W
L
E
G
D
Y
F
R
Q
K
L
K
G
Site 35
S391
G
Q
H
R
A
A
F
S
K
L
L
S
G
V
D
Site 36
S401
L
S
G
V
D
D
I
S
I
N
G
V
E
N
Q
Site 37
Y416
D
Q
Q
E
P
E
P
Y
S
D
D
D
E
I
N
Site 38
S417
Q
Q
E
P
E
P
Y
S
D
D
D
E
I
N
G
Site 39
T426
D
D
E
I
N
G
V
T
Q
G
D
R
L
R
A
Site 40
S436
D
R
L
R
A
L
K
S
R
R
Q
S
K
T
N
Site 41
S440
A
L
K
S
R
R
Q
S
K
T
N
A
I
P
L
Site 42
T442
K
S
R
R
Q
S
K
T
N
A
I
P
L
T
V
Site 43
S457
I
L
Q
S
S
V
Q
S
C
K
T
S
E
P
N
Site 44
T460
S
S
V
Q
S
C
K
T
S
E
P
N
I
S
G
Site 45
S461
S
V
Q
S
C
K
T
S
E
P
N
I
S
G
S
Site 46
S466
K
T
S
E
P
N
I
S
G
S
A
G
I
T
K
Site 47
T472
I
S
G
S
A
G
I
T
K
R
T
T
R
S
A
Site 48
T475
S
A
G
I
T
K
R
T
T
R
S
A
S
R
K
Site 49
T476
A
G
I
T
K
R
T
T
R
S
A
S
R
K
S
Site 50
S478
I
T
K
R
T
T
R
S
A
S
R
K
S
S
V
Site 51
S480
K
R
T
T
R
S
A
S
R
K
S
S
V
K
S
Site 52
S483
T
R
S
A
S
R
K
S
S
V
K
S
L
S
I
Site 53
S484
R
S
A
S
R
K
S
S
V
K
S
L
S
I
S
Site 54
S487
S
R
K
S
S
V
K
S
L
S
I
S
R
T
K
Site 55
S489
K
S
S
V
K
S
L
S
I
S
R
T
K
T
V
Site 56
S491
S
V
K
S
L
S
I
S
R
T
K
T
V
L
R
Site 57
T493
K
S
L
S
I
S
R
T
K
T
V
L
R
_
_
Site 58
T495
L
S
I
S
R
T
K
T
V
L
R
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation