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Updated November 2019
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Protein Info
Short Name:
MAGE-C1
Full Name:
Melanoma-associated antigen C1
Alias:
Cancer/testis antigen family 7, member 1; Cancer-testis antigen CT7; CT7; CT7.1; MAGC1; MAGEC1; Melanoma antigen family C, 1; MGC39366
Type:
Unknown function
Mass (Da):
123643
Number AA:
1142
UniProt ID:
O60732
International Prot ID:
IPI00299085
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
G
D
K
D
M
P
T
A
G
M
P
S
L
L
Site 2
S13
M
P
T
A
G
M
P
S
L
L
Q
S
S
S
E
Site 3
S17
G
M
P
S
L
L
Q
S
S
S
E
S
P
Q
S
Site 4
S18
M
P
S
L
L
Q
S
S
S
E
S
P
Q
S
C
Site 5
S19
P
S
L
L
Q
S
S
S
E
S
P
Q
S
C
P
Site 6
S21
L
L
Q
S
S
S
E
S
P
Q
S
C
P
E
G
Site 7
S24
S
S
S
E
S
P
Q
S
C
P
E
G
E
D
S
Site 8
S31
S
C
P
E
G
E
D
S
Q
S
P
L
Q
I
P
Site 9
S33
P
E
G
E
D
S
Q
S
P
L
Q
I
P
Q
S
Site 10
S40
S
P
L
Q
I
P
Q
S
S
P
E
S
D
D
T
Site 11
S41
P
L
Q
I
P
Q
S
S
P
E
S
D
D
T
L
Site 12
S44
I
P
Q
S
S
P
E
S
D
D
T
L
Y
P
L
Site 13
T47
S
S
P
E
S
D
D
T
L
Y
P
L
Q
S
P
Site 14
Y49
P
E
S
D
D
T
L
Y
P
L
Q
S
P
Q
S
Site 15
S53
D
T
L
Y
P
L
Q
S
P
Q
S
R
S
E
G
Site 16
S56
Y
P
L
Q
S
P
Q
S
R
S
E
G
E
D
S
Site 17
S58
L
Q
S
P
Q
S
R
S
E
G
E
D
S
S
D
Site 18
S63
S
R
S
E
G
E
D
S
S
D
P
L
Q
R
P
Site 19
S64
R
S
E
G
E
D
S
S
D
P
L
Q
R
P
P
Site 20
S76
R
P
P
E
G
K
D
S
Q
S
P
L
Q
I
P
Site 21
S78
P
E
G
K
D
S
Q
S
P
L
Q
I
P
Q
S
Site 22
S85
S
P
L
Q
I
P
Q
S
S
P
E
G
D
D
T
Site 23
S86
P
L
Q
I
P
Q
S
S
P
E
G
D
D
T
Q
Site 24
T92
S
S
P
E
G
D
D
T
Q
S
P
L
Q
N
S
Site 25
S94
P
E
G
D
D
T
Q
S
P
L
Q
N
S
Q
S
Site 26
S99
T
Q
S
P
L
Q
N
S
Q
S
S
P
E
G
K
Site 27
S101
S
P
L
Q
N
S
Q
S
S
P
E
G
K
D
S
Site 28
S102
P
L
Q
N
S
Q
S
S
P
E
G
K
D
S
L
Site 29
S108
S
S
P
E
G
K
D
S
L
S
P
L
E
I
S
Site 30
S110
P
E
G
K
D
S
L
S
P
L
E
I
S
Q
S
Site 31
S115
S
L
S
P
L
E
I
S
Q
S
P
P
E
G
E
Site 32
S117
S
P
L
E
I
S
Q
S
P
P
E
G
E
D
V
Site 33
S126
P
E
G
E
D
V
Q
S
P
L
Q
N
P
A
S
Site 34
S133
S
P
L
Q
N
P
A
S
S
F
F
S
S
A
L
Site 35
S146
A
L
L
S
I
F
Q
S
S
P
E
S
T
Q
S
Site 36
S147
L
L
S
I
F
Q
S
S
P
E
S
T
Q
S
P
Site 37
S150
I
F
Q
S
S
P
E
S
T
Q
S
P
F
E
G
Site 38
T151
F
Q
S
S
P
E
S
T
Q
S
P
F
E
G
F
Site 39
S153
S
S
P
E
S
T
Q
S
P
F
E
G
F
P
Q
Site 40
S177
A
S
S
S
T
L
V
S
I
F
Q
S
S
P
E
Site 41
S181
T
L
V
S
I
F
Q
S
S
P
E
S
T
Q
S
Site 42
S182
L
V
S
I
F
Q
S
S
P
E
S
T
Q
S
P
Site 43
S196
P
F
E
G
F
P
Q
S
P
L
Q
I
P
V
S
Site 44
S203
S
P
L
Q
I
P
V
S
R
S
F
S
S
T
L
Site 45
S212
S
F
S
S
T
L
L
S
I
F
Q
S
S
P
E
Site 46
S216
T
L
L
S
I
F
Q
S
S
P
E
R
T
Q
S
Site 47
S217
L
L
S
I
F
Q
S
S
P
E
R
T
Q
S
T
Site 48
T221
F
Q
S
S
P
E
R
T
Q
S
T
F
E
G
F
Site 49
S223
S
S
P
E
R
T
Q
S
T
F
E
G
F
A
Q
Site 50
T224
S
P
E
R
T
Q
S
T
F
E
G
F
A
Q
S
Site 51
S238
S
P
L
Q
I
P
V
S
P
S
S
S
S
T
L
Site 52
S247
S
S
S
S
T
L
L
S
L
F
Q
S
F
S
E
Site 53
S251
T
L
L
S
L
F
Q
S
F
S
E
R
T
Q
S
Site 54
S253
L
S
L
F
Q
S
F
S
E
R
T
Q
S
T
F
Site 55
S258
S
F
S
E
R
T
Q
S
T
F
E
G
F
A
Q
Site 56
T259
F
S
E
R
T
Q
S
T
F
E
G
F
A
Q
S
Site 57
S266
T
F
E
G
F
P
Q
S
P
L
Q
I
P
V
S
Site 58
S282
S
F
S
S
T
L
V
S
L
F
Q
S
S
P
E
Site 59
S286
T
L
V
S
L
F
Q
S
S
P
E
R
T
Q
S
Site 60
S287
L
V
S
L
F
Q
S
S
P
E
R
T
Q
S
T
Site 61
S293
S
S
P
E
R
T
Q
S
T
F
E
G
F
P
Q
Site 62
T294
S
P
E
R
T
Q
S
T
F
E
G
F
P
Q
S
Site 63
S301
T
F
E
G
F
P
Q
S
P
L
Q
I
P
V
S
Site 64
S308
S
P
L
Q
I
P
V
S
S
S
S
S
S
T
L
Site 65
S317
S
S
S
S
T
L
L
S
L
F
Q
S
S
P
E
Site 66
S321
T
L
L
S
L
F
Q
S
S
P
E
R
T
H
S
Site 67
S322
L
L
S
L
F
Q
S
S
P
E
R
T
H
S
T
Site 68
T326
F
Q
S
S
P
E
R
T
H
S
T
F
E
G
F
Site 69
S328
S
S
P
E
R
T
H
S
T
F
E
G
F
P
Q
Site 70
T329
S
P
E
R
T
H
S
T
F
E
G
F
P
Q
S
Site 71
S356
T
L
L
S
I
F
Q
S
S
P
E
S
A
Q
S
Site 72
S357
L
L
S
I
F
Q
S
S
P
E
S
A
Q
S
T
Site 73
S360
I
F
Q
S
S
P
E
S
A
Q
S
T
F
E
G
Site 74
S363
S
S
P
E
S
A
Q
S
T
F
E
G
F
P
Q
Site 75
T364
S
P
E
S
A
Q
S
T
F
E
G
F
P
Q
S
Site 76
S371
T
F
E
G
F
P
Q
S
P
L
Q
I
P
G
S
Site 77
S378
S
P
L
Q
I
P
G
S
P
S
F
S
S
T
L
Site 78
S387
S
F
S
S
T
L
L
S
L
F
Q
S
S
P
E
Site 79
S406
T
F
E
G
F
P
Q
S
P
L
Q
I
P
M
T
Site 80
S422
S
F
S
S
T
L
L
S
I
L
Q
S
S
P
E
Site 81
S426
T
L
L
S
I
L
Q
S
S
P
E
S
A
Q
S
Site 82
S427
L
L
S
I
L
Q
S
S
P
E
S
A
Q
S
A
Site 83
S430
I
L
Q
S
S
P
E
S
A
Q
S
A
F
E
G
Site 84
S433
S
S
P
E
S
A
Q
S
A
F
E
G
F
P
Q
Site 85
S457
S
F
S
Y
T
L
L
S
L
F
Q
S
S
P
E
Site 86
S483
S
P
L
Q
I
P
V
S
S
S
S
S
S
S
T
Site 87
S484
P
L
Q
I
P
V
S
S
S
S
S
S
S
T
L
Site 88
S486
Q
I
P
V
S
S
S
S
S
S
S
T
L
L
S
Site 89
T490
S
S
S
S
S
S
S
T
L
L
S
L
F
Q
S
Site 90
S497
T
L
L
S
L
F
Q
S
S
P
E
C
T
Q
S
Site 91
S498
L
L
S
L
F
Q
S
S
P
E
C
T
Q
S
T
Site 92
T502
F
Q
S
S
P
E
C
T
Q
S
T
F
E
G
F
Site 93
S504
S
S
P
E
C
T
Q
S
T
F
E
G
F
P
Q
Site 94
T505
S
P
E
C
T
Q
S
T
F
E
G
F
P
Q
S
Site 95
S512
T
F
E
G
F
P
Q
S
P
L
Q
I
P
Q
S
Site 96
S519
S
P
L
Q
I
P
Q
S
P
P
E
G
E
N
T
Site 97
T526
S
P
P
E
G
E
N
T
H
S
P
L
Q
I
V
Site 98
S528
P
E
G
E
N
T
H
S
P
L
Q
I
V
P
S
Site 99
S535
S
P
L
Q
I
V
P
S
L
P
E
W
E
D
S
Site 100
S542
S
L
P
E
W
E
D
S
L
S
P
H
Y
F
P
Site 101
S544
P
E
W
E
D
S
L
S
P
H
Y
F
P
Q
S
Site 102
Y547
E
D
S
L
S
P
H
Y
F
P
Q
S
P
P
Q
Site 103
S551
S
P
H
Y
F
P
Q
S
P
P
Q
G
E
D
S
Site 104
S558
S
P
P
Q
G
E
D
S
L
S
P
H
Y
F
P
Site 105
S560
P
Q
G
E
D
S
L
S
P
H
Y
F
P
Q
S
Site 106
Y579
E
D
S
L
S
P
H
Y
F
P
Q
S
P
Q
G
Site 107
S583
S
P
H
Y
F
P
Q
S
P
Q
G
E
D
S
L
Site 108
S589
Q
S
P
Q
G
E
D
S
L
S
P
H
Y
F
P
Site 109
S605
S
P
P
Q
G
E
D
S
M
S
P
L
Y
F
P
Site 110
S607
P
Q
G
E
D
S
M
S
P
L
Y
F
P
Q
S
Site 111
Y610
E
D
S
M
S
P
L
Y
F
P
Q
S
P
L
Q
Site 112
S614
S
P
L
Y
F
P
Q
S
P
L
Q
G
E
E
F
Site 113
S623
L
Q
G
E
E
F
Q
S
S
L
Q
S
P
V
S
Site 114
S624
Q
G
E
E
F
Q
S
S
L
Q
S
P
V
S
I
Site 115
S627
E
F
Q
S
S
L
Q
S
P
V
S
I
C
S
S
Site 116
S630
S
S
L
Q
S
P
V
S
I
C
S
S
S
T
P
Site 117
S633
Q
S
P
V
S
I
C
S
S
S
T
P
S
S
L
Site 118
S634
S
P
V
S
I
C
S
S
S
T
P
S
S
L
P
Site 119
S635
P
V
S
I
C
S
S
S
T
P
S
S
L
P
Q
Site 120
T636
V
S
I
C
S
S
S
T
P
S
S
L
P
Q
S
Site 121
S638
I
C
S
S
S
T
P
S
S
L
P
Q
S
F
P
Site 122
S639
C
S
S
S
T
P
S
S
L
P
Q
S
F
P
E
Site 123
S643
T
P
S
S
L
P
Q
S
F
P
E
S
S
Q
S
Site 124
S647
L
P
Q
S
F
P
E
S
S
Q
S
P
P
E
G
Site 125
S648
P
Q
S
F
P
E
S
S
Q
S
P
P
E
G
P
Site 126
S650
S
F
P
E
S
S
Q
S
P
P
E
G
P
V
Q
Site 127
S658
P
P
E
G
P
V
Q
S
P
L
H
S
P
Q
S
Site 128
S662
P
V
Q
S
P
L
H
S
P
Q
S
P
P
E
G
Site 129
S665
S
P
L
H
S
P
Q
S
P
P
E
G
M
H
S
Site 130
S672
S
P
P
E
G
M
H
S
Q
S
P
L
Q
S
P
Site 131
S674
P
E
G
M
H
S
Q
S
P
L
Q
S
P
E
S
Site 132
S678
H
S
Q
S
P
L
Q
S
P
E
S
A
P
E
G
Site 133
S681
S
P
L
Q
S
P
E
S
A
P
E
G
E
D
S
Site 134
S688
S
A
P
E
G
E
D
S
L
S
P
L
Q
I
P
Site 135
S690
P
E
G
E
D
S
L
S
P
L
Q
I
P
Q
S
Site 136
S697
S
P
L
Q
I
P
Q
S
P
L
E
G
E
D
S
Site 137
S704
S
P
L
E
G
E
D
S
L
S
S
L
H
F
P
Site 138
S706
L
E
G
E
D
S
L
S
S
L
H
F
P
Q
S
Site 139
S707
E
G
E
D
S
L
S
S
L
H
F
P
Q
S
P
Site 140
S713
S
S
L
H
F
P
Q
S
P
P
E
W
E
D
S
Site 141
S720
S
P
P
E
W
E
D
S
L
S
P
L
H
F
P
Site 142
S722
P
E
W
E
D
S
L
S
P
L
H
F
P
Q
F
Site 143
S738
P
Q
G
E
D
F
Q
S
S
L
Q
S
P
V
S
Site 144
S739
Q
G
E
D
F
Q
S
S
L
Q
S
P
V
S
I
Site 145
S742
D
F
Q
S
S
L
Q
S
P
V
S
I
C
S
S
Site 146
S745
S
S
L
Q
S
P
V
S
I
C
S
S
S
T
S
Site 147
S752
S
I
C
S
S
S
T
S
L
S
L
P
Q
S
F
Site 148
S754
C
S
S
S
T
S
L
S
L
P
Q
S
F
P
E
Site 149
S758
T
S
L
S
L
P
Q
S
F
P
E
S
P
Q
S
Site 150
S762
L
P
Q
S
F
P
E
S
P
Q
S
P
P
E
G
Site 151
S765
S
F
P
E
S
P
Q
S
P
P
E
G
P
A
Q
Site 152
S773
P
P
E
G
P
A
Q
S
P
L
Q
R
P
V
S
Site 153
S780
S
P
L
Q
R
P
V
S
S
F
F
S
Y
T
L
Site 154
S789
F
F
S
Y
T
L
A
S
L
L
Q
S
S
H
E
Site 155
S793
T
L
A
S
L
L
Q
S
S
H
E
S
P
Q
S
Site 156
S794
L
A
S
L
L
Q
S
S
H
E
S
P
Q
S
P
Site 157
S797
L
L
Q
S
S
H
E
S
P
Q
S
P
P
E
G
Site 158
S800
S
S
H
E
S
P
Q
S
P
P
E
G
P
A
Q
Site 159
S808
P
P
E
G
P
A
Q
S
P
L
Q
S
P
V
S
Site 160
S812
P
A
Q
S
P
L
Q
S
P
V
S
S
F
P
S
Site 161
S815
S
P
L
Q
S
P
V
S
S
F
P
S
S
T
S
Site 162
S816
P
L
Q
S
P
V
S
S
F
P
S
S
T
S
S
Site 163
S819
S
P
V
S
S
F
P
S
S
T
S
S
S
L
S
Site 164
S820
P
V
S
S
F
P
S
S
T
S
S
S
L
S
Q
Site 165
T821
V
S
S
F
P
S
S
T
S
S
S
L
S
Q
S
Site 166
S822
S
S
F
P
S
S
T
S
S
S
L
S
Q
S
S
Site 167
S823
S
F
P
S
S
T
S
S
S
L
S
Q
S
S
P
Site 168
S824
F
P
S
S
T
S
S
S
L
S
Q
S
S
P
V
Site 169
S826
S
S
T
S
S
S
L
S
Q
S
S
P
V
S
S
Site 170
S828
T
S
S
S
L
S
Q
S
S
P
V
S
S
F
P
Site 171
S829
S
S
S
L
S
Q
S
S
P
V
S
S
F
P
S
Site 172
S832
L
S
Q
S
S
P
V
S
S
F
P
S
S
T
S
Site 173
S833
S
Q
S
S
P
V
S
S
F
P
S
S
T
S
S
Site 174
S837
P
V
S
S
F
P
S
S
T
S
S
S
L
S
K
Site 175
T838
V
S
S
F
P
S
S
T
S
S
S
L
S
K
S
Site 176
S839
S
S
F
P
S
S
T
S
S
S
L
S
K
S
S
Site 177
S840
S
F
P
S
S
T
S
S
S
L
S
K
S
S
P
Site 178
S841
F
P
S
S
T
S
S
S
L
S
K
S
S
P
E
Site 179
S843
S
S
T
S
S
S
L
S
K
S
S
P
E
S
P
Site 180
S845
T
S
S
S
L
S
K
S
S
P
E
S
P
L
Q
Site 181
S846
S
S
S
L
S
K
S
S
P
E
S
P
L
Q
S
Site 182
S849
L
S
K
S
S
P
E
S
P
L
Q
S
P
V
I
Site 183
S853
S
P
E
S
P
L
Q
S
P
V
I
S
F
S
S
Site 184
S859
Q
S
P
V
I
S
F
S
S
S
T
S
L
S
P
Site 185
S863
I
S
F
S
S
S
T
S
L
S
P
F
S
E
E
Site 186
S865
F
S
S
S
T
S
L
S
P
F
S
E
E
S
S
Site 187
S868
S
T
S
L
S
P
F
S
E
E
S
S
S
P
V
Site 188
S871
L
S
P
F
S
E
E
S
S
S
P
V
D
E
Y
Site 189
S872
S
P
F
S
E
E
S
S
S
P
V
D
E
Y
T
Site 190
S873
P
F
S
E
E
S
S
S
P
V
D
E
Y
T
S
Site 191
Y878
S
S
S
P
V
D
E
Y
T
S
S
S
D
T
L
Site 192
T879
S
S
P
V
D
E
Y
T
S
S
S
D
T
L
L
Site 193
S880
S
P
V
D
E
Y
T
S
S
S
D
T
L
L
E
Site 194
S881
P
V
D
E
Y
T
S
S
S
D
T
L
L
E
S
Site 195
S882
V
D
E
Y
T
S
S
S
D
T
L
L
E
S
D
Site 196
T884
E
Y
T
S
S
S
D
T
L
L
E
S
D
S
L
Site 197
S888
S
S
D
T
L
L
E
S
D
S
L
T
D
S
E
Site 198
S890
D
T
L
L
E
S
D
S
L
T
D
S
E
S
L
Site 199
T892
L
L
E
S
D
S
L
T
D
S
E
S
L
I
E
Site 200
S894
E
S
D
S
L
T
D
S
E
S
L
I
E
S
E
Site 201
S896
D
S
L
T
D
S
E
S
L
I
E
S
E
P
L
Site 202
S900
D
S
E
S
L
I
E
S
E
P
L
F
T
Y
T
Site 203
T905
I
E
S
E
P
L
F
T
Y
T
L
D
E
K
V
Site 204
T936
I
T
K
A
E
M
L
T
N
V
I
S
R
Y
T
Site 205
S973
R
E
V
D
P
D
D
S
Y
V
F
V
N
T
L
Site 206
Y974
E
V
D
P
D
D
S
Y
V
F
V
N
T
L
D
Site 207
T979
D
S
Y
V
F
V
N
T
L
D
L
T
S
E
G
Site 208
S984
V
N
T
L
D
L
T
S
E
G
C
L
S
D
E
Site 209
S989
L
T
S
E
G
C
L
S
D
E
Q
G
M
S
Q
Site 210
S995
L
S
D
E
Q
G
M
S
Q
N
R
L
L
I
L
Site 211
Y1053
K
V
W
V
Q
E
H
Y
L
E
Y
R
E
V
P
Site 212
S1062
E
Y
R
E
V
P
N
S
S
P
P
R
Y
E
F
Site 213
S1063
Y
R
E
V
P
N
S
S
P
P
R
Y
E
F
L
Site 214
Y1067
P
N
S
S
P
P
R
Y
E
F
L
W
G
P
R
Site 215
S1077
L
W
G
P
R
A
H
S
E
V
I
K
R
K
V
Site 216
T1098
L
K
N
T
V
P
I
T
F
P
S
S
Y
K
D
Site 217
S1102
V
P
I
T
F
P
S
S
Y
K
D
A
L
K
D
Site 218
T1120
R
A
Q
A
I
I
D
T
T
D
D
S
T
A
T
Site 219
S1124
I
I
D
T
T
D
D
S
T
A
T
E
S
A
S
Site 220
T1125
I
D
T
T
D
D
S
T
A
T
E
S
A
S
S
Site 221
T1127
T
T
D
D
S
T
A
T
E
S
A
S
S
S
V
Site 222
S1129
D
D
S
T
A
T
E
S
A
S
S
S
V
M
S
Site 223
S1131
S
T
A
T
E
S
A
S
S
S
V
M
S
P
S
Site 224
S1132
T
A
T
E
S
A
S
S
S
V
M
S
P
S
F
Site 225
S1133
A
T
E
S
A
S
S
S
V
M
S
P
S
F
S
Site 226
S1136
S
A
S
S
S
V
M
S
P
S
F
S
S
E
_
Site 227
S1138
S
S
S
V
M
S
P
S
F
S
S
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation