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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX2
Full Name:
Sorting nexin-2
Alias:
Transformation-related gene 9 protein; TRG-9
Type:
Vesicle protein
Mass (Da):
58471
Number AA:
519
UniProt ID:
O60749
International Prot ID:
IPI00299095
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0006897
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
P
L
G
D
G
K
P
T
D
F
E
D
L
E
D
Site 2
T29
E
D
G
E
D
L
F
T
S
T
V
S
T
L
E
Site 3
S30
D
G
E
D
L
F
T
S
T
V
S
T
L
E
S
Site 4
T31
G
E
D
L
F
T
S
T
V
S
T
L
E
S
S
Site 5
S33
D
L
F
T
S
T
V
S
T
L
E
S
S
P
S
Site 6
T34
L
F
T
S
T
V
S
T
L
E
S
S
P
S
S
Site 7
S37
S
T
V
S
T
L
E
S
S
P
S
S
P
E
P
Site 8
S38
T
V
S
T
L
E
S
S
P
S
S
P
E
P
A
Site 9
S40
S
T
L
E
S
S
P
S
S
P
E
P
A
S
L
Site 10
S41
T
L
E
S
S
P
S
S
P
E
P
A
S
L
P
Site 11
S46
P
S
S
P
E
P
A
S
L
P
A
E
D
I
S
Site 12
S53
S
L
P
A
E
D
I
S
A
N
S
N
G
P
K
Site 13
S56
A
E
D
I
S
A
N
S
N
G
P
K
P
T
E
Site 14
T78
E
D
L
F
A
E
A
T
E
E
V
S
L
D
S
Site 15
S85
T
E
E
V
S
L
D
S
P
E
R
E
P
I
L
Site 16
S93
P
E
R
E
P
I
L
S
S
E
P
S
P
A
V
Site 17
S94
E
R
E
P
I
L
S
S
E
P
S
P
A
V
T
Site 18
T101
S
E
P
S
P
A
V
T
P
V
T
P
T
T
L
Site 19
T104
S
P
A
V
T
P
V
T
P
T
T
L
I
A
P
Site 20
T106
A
V
T
P
V
T
P
T
T
L
I
A
P
R
I
Site 21
S117
A
P
R
I
E
S
K
S
M
S
A
P
V
I
F
Site 22
S119
R
I
E
S
K
S
M
S
A
P
V
I
F
D
R
Site 23
S127
A
P
V
I
F
D
R
S
R
E
E
I
E
E
E
Site 24
S147
F
D
I
E
I
G
V
S
D
P
E
K
V
G
D
Site 25
Y159
V
G
D
G
M
N
A
Y
M
A
Y
R
V
T
T
Site 26
T165
A
Y
M
A
Y
R
V
T
T
K
T
S
L
S
M
Site 27
T166
Y
M
A
Y
R
V
T
T
K
T
S
L
S
M
F
Site 28
T168
A
Y
R
V
T
T
K
T
S
L
S
M
F
S
K
Site 29
S169
Y
R
V
T
T
K
T
S
L
S
M
F
S
K
S
Site 30
S171
V
T
T
K
T
S
L
S
M
F
S
K
S
E
F
Site 31
S174
K
T
S
L
S
M
F
S
K
S
E
F
S
V
K
Site 32
S176
S
L
S
M
F
S
K
S
E
F
S
V
K
R
R
Site 33
S179
M
F
S
K
S
E
F
S
V
K
R
R
F
S
D
Site 34
S185
F
S
V
K
R
R
F
S
D
F
L
G
L
H
S
Site 35
S192
S
D
F
L
G
L
H
S
K
L
A
S
K
Y
L
Site 36
S196
G
L
H
S
K
L
A
S
K
Y
L
H
V
G
Y
Site 37
Y203
S
K
Y
L
H
V
G
Y
I
V
P
P
A
P
E
Site 38
S226
V
K
V
G
K
E
D
S
S
S
T
E
F
V
E
Site 39
S227
K
V
G
K
E
D
S
S
S
T
E
F
V
E
K
Site 40
S228
V
G
K
E
D
S
S
S
T
E
F
V
E
K
R
Site 41
Y242
R
R
A
A
L
E
R
Y
L
Q
R
T
V
K
H
Site 42
T246
L
E
R
Y
L
Q
R
T
V
K
H
P
T
L
L
Site 43
S264
D
L
R
Q
F
L
E
S
S
E
L
P
R
A
V
Site 44
S265
L
R
Q
F
L
E
S
S
E
L
P
R
A
V
N
Site 45
T273
E
L
P
R
A
V
N
T
Q
A
L
S
G
A
G
Site 46
S277
A
V
N
T
Q
A
L
S
G
A
G
I
L
R
M
Site 47
T358
L
G
N
S
E
D
H
T
A
L
S
R
A
L
S
Site 48
S361
S
E
D
H
T
A
L
S
R
A
L
S
Q
L
A
Site 49
S365
T
A
L
S
R
A
L
S
Q
L
A
E
V
E
E
Site 50
T470
D
F
E
Q
I
S
K
T
I
R
K
E
V
G
R
Site 51
T488
E
R
V
K
D
F
K
T
V
I
I
K
Y
L
E
Site 52
S496
V
I
I
K
Y
L
E
S
L
V
Q
T
Q
Q
Q
Site 53
T500
Y
L
E
S
L
V
Q
T
Q
Q
Q
L
I
K
Y
Site 54
Y507
T
Q
Q
Q
L
I
K
Y
W
E
A
F
L
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation