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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DPM1
Full Name:
Dolichol-phosphate mannosyltransferase
Alias:
CDGIE; Dolichol-phosphate mannose synthase; Dolichyl-phosphate beta-D-mannosyltransferase; Dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; DPM synthase; Mannose-P-dolichol synthase; MPD synthase; MPDS
Type:
Glycan Metabolism - N-glycan biosynthesis; EC 2.4.1.83; Transferase
Mass (Da):
29634
Number AA:
260
UniProt ID:
O60762
International Prot ID:
IPI00022018
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0033185
GO:0005789
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0004582
GO:0004169
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006506
GO:0019348
GO:0018406
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
L
E
V
S
R
S
P
Site 2
S7
_
M
A
S
L
E
V
S
R
S
P
R
R
S
R
Site 3
S9
A
S
L
E
V
S
R
S
P
R
R
S
R
R
E
Site 4
S13
V
S
R
S
P
R
R
S
R
R
E
L
E
V
R
Site 5
S21
R
R
E
L
E
V
R
S
P
R
Q
N
K
Y
S
Site 6
Y27
R
S
P
R
Q
N
K
Y
S
V
L
L
P
T
Y
Site 7
S28
S
P
R
Q
N
K
Y
S
V
L
L
P
T
Y
N
Site 8
Y34
Y
S
V
L
L
P
T
Y
N
E
R
E
N
L
P
Site 9
S52
W
L
L
V
K
S
F
S
E
S
G
I
N
Y
E
Site 10
S67
I
I
I
I
D
D
G
S
P
D
G
T
R
D
V
Site 11
T71
D
D
G
S
P
D
G
T
R
D
V
A
E
Q
L
Site 12
S84
Q
L
E
K
I
Y
G
S
D
R
I
L
L
R
P
Site 13
Y102
K
L
G
L
G
T
A
Y
I
H
G
M
K
H
A
Site 14
Y113
M
K
H
A
T
G
N
Y
I
I
I
M
D
A
D
Site 15
S144
E
G
N
F
D
I
V
S
G
T
R
Y
K
G
N
Site 16
Y148
D
I
V
S
G
T
R
Y
K
G
N
G
G
V
Y
Site 17
S165
D
L
K
R
K
I
I
S
R
G
A
N
F
L
T
Site 18
T172
S
R
G
A
N
F
L
T
Q
I
L
L
R
P
G
Site 19
T184
R
P
G
A
S
D
L
T
G
S
F
R
L
Y
R
Site 20
S186
G
A
S
D
L
T
G
S
F
R
L
Y
R
K
E
Site 21
Y190
L
T
G
S
F
R
L
Y
R
K
E
V
L
E
K
Site 22
Y207
E
K
C
V
S
K
G
Y
V
F
Q
M
E
M
I
Site 23
T223
R
A
R
Q
L
N
Y
T
I
G
E
V
P
I
S
Site 24
Y236
I
S
F
V
D
R
V
Y
G
E
S
K
L
G
G
Site 25
S239
V
D
R
V
Y
G
E
S
K
L
G
G
N
E
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation