PhosphoNET

           
Protein Info 
   
Short Name:  DPM1
Full Name:  Dolichol-phosphate mannosyltransferase
Alias:  CDGIE; Dolichol-phosphate mannose synthase; Dolichyl-phosphate beta-D-mannosyltransferase; Dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; DPM synthase; Mannose-P-dolichol synthase; MPD synthase; MPDS
Type:  Glycan Metabolism - N-glycan biosynthesis; EC 2.4.1.83; Transferase
Mass (Da):  29634
Number AA:  260
UniProt ID:  O60762
International Prot ID:  IPI00022018
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0033185  GO:0005789  GO:0005624 Uniprot OncoNet
Molecular Function:  GO:0004582  GO:0004169  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006506  GO:0019348  GO:0018406 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S3_____MASLEVSRSP
Site 2S7_MASLEVSRSPRRSR
Site 3S9ASLEVSRSPRRSRRE
Site 4S13VSRSPRRSRRELEVR
Site 5S21RRELEVRSPRQNKYS
Site 6Y27RSPRQNKYSVLLPTY
Site 7S28SPRQNKYSVLLPTYN
Site 8Y34YSVLLPTYNERENLP
Site 9S52WLLVKSFSESGINYE
Site 10S67IIIIDDGSPDGTRDV
Site 11T71DDGSPDGTRDVAEQL
Site 12S84QLEKIYGSDRILLRP
Site 13Y102KLGLGTAYIHGMKHA
Site 14Y113MKHATGNYIIIMDAD
Site 15S144EGNFDIVSGTRYKGN
Site 16Y148DIVSGTRYKGNGGVY
Site 17S165DLKRKIISRGANFLT
Site 18T172SRGANFLTQILLRPG
Site 19T184RPGASDLTGSFRLYR
Site 20S186GASDLTGSFRLYRKE
Site 21Y190LTGSFRLYRKEVLEK
Site 22Y207EKCVSKGYVFQMEMI
Site 23T223RARQLNYTIGEVPIS
Site 24Y236ISFVDRVYGESKLGG
Site 25S239VDRVYGESKLGGNEI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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