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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
USO1
Full Name:
General vesicular transport factor p115
Alias:
General vesicular transport factor p115;Protein USO1 homolog;Transcytosis-associated protein;Vesicle-docking protein; P115; Transcytosis associated protein; USO1, vesicle docking protein; VDP; Vesicle docking protein
Type:
Vesicle protein
Mass (Da):
107895
Number AA:
962
UniProt ID:
O60763
International Prot ID:
IPI00743314
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0005829
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0048280
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
R
G
V
M
G
G
Q
S
A
G
P
Q
H
T
E
Site 2
S32
K
L
C
D
R
V
A
S
S
T
L
L
D
D
R
Site 3
T34
C
D
R
V
A
S
S
T
L
L
D
D
R
R
N
Site 4
S48
N
A
V
R
A
L
K
S
L
S
K
K
Y
R
L
Site 5
S50
V
R
A
L
K
S
L
S
K
K
Y
R
L
E
V
Site 6
T71
H
L
I
H
V
L
Q
T
D
R
S
D
S
E
I
Site 7
S74
H
V
L
Q
T
D
R
S
D
S
E
I
I
G
Y
Site 8
S76
L
Q
T
D
R
S
D
S
E
I
I
G
Y
A
L
Site 9
Y81
S
D
S
E
I
I
G
Y
A
L
D
T
L
Y
N
Site 10
Y87
G
Y
A
L
D
T
L
Y
N
I
I
S
N
E
E
Site 11
S91
D
T
L
Y
N
I
I
S
N
E
E
E
E
E
V
Site 12
S102
E
E
E
V
E
E
N
S
T
R
Q
S
E
D
L
Site 13
T103
E
E
V
E
E
N
S
T
R
Q
S
E
D
L
G
Site 14
S106
E
E
N
S
T
R
Q
S
E
D
L
G
S
Q
F
Site 15
S111
R
Q
S
E
D
L
G
S
Q
F
T
E
I
F
I
Site 16
T147
W
P
G
V
K
L
L
T
S
L
L
K
Q
L
G
Site 17
S148
P
G
V
K
L
L
T
S
L
L
K
Q
L
G
P
Site 18
S178
L
M
D
L
L
A
D
S
R
E
V
I
R
N
D
Site 19
S218
E
R
L
L
D
I
I
S
E
E
G
N
S
D
G
Site 20
S223
I
I
S
E
E
G
N
S
D
G
G
I
V
V
E
Site 21
T294
V
R
V
L
V
S
P
T
N
P
P
G
A
T
S
Site 22
S301
T
N
P
P
G
A
T
S
S
C
Q
K
A
M
F
Site 23
S302
N
P
P
G
A
T
S
S
C
Q
K
A
M
F
Q
Site 24
Y350
G
C
Q
V
N
Q
D
Y
F
A
S
V
N
A
P
Site 25
S353
V
N
Q
D
Y
F
A
S
V
N
A
P
S
N
P
Site 26
S358
F
A
S
V
N
A
P
S
N
P
P
R
P
A
I
Site 27
T465
L
L
R
V
Q
L
A
T
S
I
G
N
P
P
V
Site 28
S473
S
I
G
N
P
P
V
S
L
L
Q
Q
C
T
N
Site 29
S483
Q
Q
C
T
N
I
L
S
Q
G
S
K
I
Q
T
Site 30
S486
T
N
I
L
S
Q
G
S
K
I
Q
T
R
V
G
Site 31
S555
S
I
Y
F
N
D
N
S
L
E
S
Y
M
K
E
Site 32
Y559
N
D
N
S
L
E
S
Y
M
K
E
K
L
K
Q
Site 33
Y590
F
I
S
K
H
E
L
Y
S
R
A
S
Q
K
P
Site 34
S594
H
E
L
Y
S
R
A
S
Q
K
P
Q
P
N
F
Site 35
S603
K
P
Q
P
N
F
P
S
P
E
Y
M
I
F
D
Site 36
Y606
P
N
F
P
S
P
E
Y
M
I
F
D
H
E
F
Site 37
T625
K
E
L
E
G
V
I
T
K
A
I
Y
K
S
S
Site 38
Y629
G
V
I
T
K
A
I
Y
K
S
S
E
E
D
K
Site 39
T644
K
E
E
E
V
K
K
T
L
E
Q
H
D
N
I
Site 40
Y655
H
D
N
I
V
T
H
Y
K
N
M
I
R
E
Q
Site 41
T675
E
L
R
Q
Q
V
S
T
L
K
C
Q
N
E
Q
Site 42
T688
E
Q
L
Q
T
A
V
T
Q
Q
V
S
Q
I
Q
Site 43
Y701
I
Q
Q
H
K
D
Q
Y
N
L
L
K
I
Q
L
Site 44
Y718
D
N
Q
H
Q
G
S
Y
S
E
G
A
Q
M
N
Site 45
S719
N
Q
H
Q
G
S
Y
S
E
G
A
Q
M
N
G
Site 46
S751
R
N
Q
E
L
L
Q
S
Q
L
T
E
K
D
S
Site 47
T754
E
L
L
Q
S
Q
L
T
E
K
D
S
M
I
E
Site 48
S758
S
Q
L
T
E
K
D
S
M
I
E
N
M
K
S
Site 49
S765
S
M
I
E
N
M
K
S
S
Q
T
S
G
T
N
Site 50
S766
M
I
E
N
M
K
S
S
Q
T
S
G
T
N
E
Site 51
S769
N
M
K
S
S
Q
T
S
G
T
N
E
Q
S
S
Site 52
T771
K
S
S
Q
T
S
G
T
N
E
Q
S
S
A
I
Site 53
S775
T
S
G
T
N
E
Q
S
S
A
I
V
S
A
R
Site 54
S776
S
G
T
N
E
Q
S
S
A
I
V
S
A
R
D
Site 55
S780
E
Q
S
S
A
I
V
S
A
R
D
S
E
Q
V
Site 56
S784
A
I
V
S
A
R
D
S
E
Q
V
A
E
L
K
Site 57
S799
Q
E
L
A
T
L
K
S
Q
L
N
S
Q
S
V
Site 58
S803
T
L
K
S
Q
L
N
S
Q
S
V
E
I
T
K
Site 59
S805
K
S
Q
L
N
S
Q
S
V
E
I
T
K
L
Q
Site 60
S828
K
T
E
A
F
A
K
S
V
E
V
Q
G
E
T
Site 61
T843
E
T
I
I
A
T
K
T
T
D
V
E
G
R
L
Site 62
S851
T
D
V
E
G
R
L
S
A
L
L
Q
E
T
K
Site 63
T872
K
A
L
S
E
E
R
T
A
I
K
E
Q
L
D
Site 64
S880
A
I
K
E
Q
L
D
S
S
N
S
T
I
A
I
Site 65
S883
E
Q
L
D
S
S
N
S
T
I
A
I
L
Q
T
Site 66
T900
D
K
L
E
L
E
I
T
D
S
K
K
E
Q
D
Site 67
S902
L
E
L
E
I
T
D
S
K
K
E
Q
D
D
L
Site 68
S922
D
Q
D
Q
K
I
L
S
L
K
N
K
L
K
D
Site 69
S942
E
E
E
D
E
L
E
S
G
D
Q
E
D
E
D
Site 70
S952
Q
E
D
E
D
D
E
S
E
D
P
G
K
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation