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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF354A
Full Name:
Zinc finger protein 354A
Alias:
Transcription factor 17;Zinc finger protein eZNF
Type:
Mass (Da):
69237
Number AA:
605
UniProt ID:
O60765
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
E
W
R
K
L
A
P
S
Q
R
N
L
Y
R
D
Site 2
Y39
A
P
S
Q
R
N
L
Y
R
D
V
M
L
E
N
Site 3
Y47
R
D
V
M
L
E
N
Y
R
N
L
V
S
L
G
Site 4
S80
W
E
V
E
K
D
G
S
G
V
S
S
L
G
S
Site 5
S83
E
K
D
G
S
G
V
S
S
L
G
S
K
S
S
Site 6
S84
K
D
G
S
G
V
S
S
L
G
S
K
S
S
H
Site 7
S87
S
G
V
S
S
L
G
S
K
S
S
H
K
T
T
Site 8
S89
V
S
S
L
G
S
K
S
S
H
K
T
T
K
S
Site 9
S90
S
S
L
G
S
K
S
S
H
K
T
T
K
S
T
Site 10
T93
G
S
K
S
S
H
K
T
T
K
S
T
Q
T
Q
Site 11
T94
S
K
S
S
H
K
T
T
K
S
T
Q
T
Q
D
Site 12
S96
S
S
H
K
T
T
K
S
T
Q
T
Q
D
S
S
Site 13
T97
S
H
K
T
T
K
S
T
Q
T
Q
D
S
S
F
Site 14
T99
K
T
T
K
S
T
Q
T
Q
D
S
S
F
Q
G
Site 15
S102
K
S
T
Q
T
Q
D
S
S
F
Q
G
L
I
L
Site 16
S103
S
T
Q
T
Q
D
S
S
F
Q
G
L
I
L
K
Site 17
S112
Q
G
L
I
L
K
R
S
N
R
N
V
P
W
D
Site 18
Y128
K
L
E
K
P
Y
I
Y
E
G
R
L
E
K
K
Site 19
S141
K
K
Q
D
K
K
G
S
F
Q
I
V
S
A
T
Site 20
S146
K
G
S
F
Q
I
V
S
A
T
H
K
K
I
P
Site 21
T154
A
T
H
K
K
I
P
T
I
E
R
S
H
K
N
Site 22
T162
I
E
R
S
H
K
N
T
E
L
S
Q
N
F
S
Site 23
S165
S
H
K
N
T
E
L
S
Q
N
F
S
P
K
S
Site 24
S169
T
E
L
S
Q
N
F
S
P
K
S
V
L
I
R
Site 25
S172
S
Q
N
F
S
P
K
S
V
L
I
R
Q
Q
I
Site 26
T185
Q
I
L
P
R
E
K
T
P
P
K
C
E
I
Q
Site 27
S200
G
N
S
L
K
Q
N
S
Q
L
L
N
Q
P
K
Site 28
Y214
K
I
T
A
D
K
R
Y
K
C
S
L
C
E
K
Site 29
T222
K
C
S
L
C
E
K
T
F
I
N
T
S
S
L
Site 30
S227
E
K
T
F
I
N
T
S
S
L
R
K
H
E
K
Site 31
S228
K
T
F
I
N
T
S
S
L
R
K
H
E
K
N
Site 32
S237
R
K
H
E
K
N
H
S
G
E
K
L
F
K
C
Site 33
S248
L
F
K
C
K
E
C
S
K
A
F
S
Q
S
S
Site 34
S252
K
E
C
S
K
A
F
S
Q
S
S
A
L
I
Q
Site 35
Y270
T
H
T
G
E
K
P
Y
I
C
K
E
C
G
K
Site 36
T280
K
E
C
G
K
A
F
T
L
S
T
S
L
Y
K
Site 37
S284
K
A
F
T
L
S
T
S
L
Y
K
H
L
R
T
Site 38
Y286
F
T
L
S
T
S
L
Y
K
H
L
R
T
H
T
Site 39
T291
S
L
Y
K
H
L
R
T
H
T
V
E
K
S
Y
Site 40
T293
Y
K
H
L
R
T
H
T
V
E
K
S
Y
R
C
Site 41
S306
R
C
K
E
C
G
K
S
F
S
R
R
S
G
L
Site 42
S308
K
E
C
G
K
S
F
S
R
R
S
G
L
F
I
Site 43
S311
G
K
S
F
S
R
R
S
G
L
F
I
H
Q
K
Site 44
Y328
A
E
E
N
P
C
K
Y
N
P
G
R
K
A
S
Site 45
S335
Y
N
P
G
R
K
A
S
S
C
S
T
S
L
S
Site 46
S336
N
P
G
R
K
A
S
S
C
S
T
S
L
S
G
Site 47
S338
G
R
K
A
S
S
C
S
T
S
L
S
G
C
Q
Site 48
T339
R
K
A
S
S
C
S
T
S
L
S
G
C
Q
R
Site 49
S340
K
A
S
S
C
S
T
S
L
S
G
C
Q
R
I
Site 50
S342
S
S
C
S
T
S
L
S
G
C
Q
R
I
H
S
Site 51
S349
S
G
C
Q
R
I
H
S
R
K
K
S
Y
L
C
Site 52
S353
R
I
H
S
R
K
K
S
Y
L
C
N
E
C
G
Site 53
Y354
I
H
S
R
K
K
S
Y
L
C
N
E
C
G
N
Site 54
T362
L
C
N
E
C
G
N
T
F
K
S
S
S
S
L
Site 55
S365
E
C
G
N
T
F
K
S
S
S
S
L
R
Y
H
Site 56
S366
C
G
N
T
F
K
S
S
S
S
L
R
Y
H
Q
Site 57
S367
G
N
T
F
K
S
S
S
S
L
R
Y
H
Q
R
Site 58
S368
N
T
F
K
S
S
S
S
L
R
Y
H
Q
R
I
Site 59
Y371
K
S
S
S
S
L
R
Y
H
Q
R
I
H
T
G
Site 60
T377
R
Y
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 61
S385
G
E
K
P
F
K
C
S
E
C
G
R
A
F
S
Site 62
S392
S
E
C
G
R
A
F
S
Q
S
A
S
L
I
Q
Site 63
S394
C
G
R
A
F
S
Q
S
A
S
L
I
Q
H
E
Site 64
S396
R
A
F
S
Q
S
A
S
L
I
Q
H
E
R
I
Site 65
T405
I
Q
H
E
R
I
H
T
G
E
K
P
Y
R
C
Site 66
Y410
I
H
T
G
E
K
P
Y
R
C
N
E
C
G
K
Site 67
S421
E
C
G
K
G
F
T
S
I
S
R
L
N
R
H
Site 68
S423
G
K
G
F
T
S
I
S
R
L
N
R
H
R
I
Site 69
Y438
I
H
T
G
E
K
F
Y
N
C
N
E
C
G
K
Site 70
S451
G
K
A
L
S
S
H
S
T
L
I
I
H
E
R
Site 71
T452
K
A
L
S
S
H
S
T
L
I
I
H
E
R
I
Site 72
T461
I
I
H
E
R
I
H
T
G
E
K
P
C
K
C
Site 73
S478
C
G
K
A
F
R
Q
S
S
A
L
I
Q
H
Q
Site 74
S479
G
K
A
F
R
Q
S
S
A
L
I
Q
H
Q
R
Site 75
T489
I
Q
H
Q
R
M
H
T
G
E
R
P
Y
K
C
Site 76
Y494
M
H
T
G
E
R
P
Y
K
C
N
E
C
G
K
Site 77
S507
G
K
T
F
R
C
N
S
S
L
S
N
H
Q
R
Site 78
S508
K
T
F
R
C
N
S
S
L
S
N
H
Q
R
I
Site 79
T517
S
N
H
Q
R
I
H
T
G
E
K
P
Y
R
C
Site 80
S530
R
C
E
E
C
G
I
S
F
G
Q
S
S
A
L
Site 81
S534
C
G
I
S
F
G
Q
S
S
A
L
I
Q
H
R
Site 82
T545
I
Q
H
R
R
I
H
T
G
E
K
P
F
K
C
Site 83
T558
K
C
N
T
C
G
K
T
F
R
Q
S
S
S
R
Site 84
S562
C
G
K
T
F
R
Q
S
S
S
R
I
A
H
Q
Site 85
S563
G
K
T
F
R
Q
S
S
S
R
I
A
H
Q
R
Site 86
S564
K
T
F
R
Q
S
S
S
R
I
A
H
Q
R
I
Site 87
T573
I
A
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 88
Y578
I
H
T
G
E
K
P
Y
E
C
N
T
C
G
K
Site 89
S591
G
K
L
F
N
H
R
S
S
L
T
N
H
Y
K
Site 90
S592
K
L
F
N
H
R
S
S
L
T
N
H
Y
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation