PhosphoNET

           
Protein Info 
   
Short Name:  PQBP1
Full Name:  Polyglutamine-binding protein 1
Alias:  38 kDa nuclear protein containing a WW domain; MRX55; MRXS8; Polyglutamine binding protein 1; Polyglutamine tract-binding protein 1; PQBP-1; RENS1; SHS
Type:  Transcription, coactivator/corepressor
Mass (Da):  30472
Number AA:  265
UniProt ID:  O60828
International Prot ID:  IPI00024698
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0003713   PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y33EEIIAEDYDDDPVDY
Site 2Y40YDDDPVDYEATRLEG
Site 3S51RLEGLPPSWYKVFDP
Site 4Y53EGLPPSWYKVFDPSC
Site 5Y65PSCGLPYYWNADTDL
Site 6S74NADTDLVSWLSPHDP
Site 7S77TDLVSWLSPHDPNSV
Site 8S83LSPHDPNSVVTKSAK
Site 9S88PNSVVTKSAKKLRSS
Site 10S94KSAKKLRSSNADAEE
Site 11S95SAKKLRSSNADAEEK
Site 12S106AEEKLDRSHDKSDRG
Site 13S110LDRSHDKSDRGHDKS
Site 14S117SDRGHDKSDRSHEKL
Site 15S120GHDKSDRSHEKLDRG
Site 16S131LDRGHDKSDRGHDKS
Site 17S138SDRGHDKSDRDRERG
Site 18Y146DRDRERGYDKVDRER
Site 19Y165ERDRDRGYDKADREE
Site 20Y187RREELAPYPKSKKAV
Site 21S190ELAPYPKSKKAVSRK
Site 22S195PKSKKAVSRKDEELD
Site 23S208LDPMDPSSYSDAPRG
Site 24Y209DPMDPSSYSDAPRGT
Site 25S210PMDPSSYSDAPRGTW
Site 26T216YSDAPRGTWSTGLPK
Site 27T219APRGTWSTGLPKRNE
Site 28T229PKRNEAKTGADTTAA
Site 29T233EAKTGADTTAAGPLF
Site 30T234AKTGADTTAAGPLFQ
Site 31Y245PLFQQRPYPSPGAVL
Site 32S247FQQRPYPSPGAVLRA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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