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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMP20
Full Name:
Matrix metalloproteinase-20
Alias:
Enamel metalloproteinase;Enamelysin
Type:
Mass (Da):
54360
Number AA:
483
UniProt ID:
O60882
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
A
P
S
L
V
A
A
S
P
R
T
W
R
N
N
Site 2
T33
L
V
A
A
S
P
R
T
W
R
N
N
Y
R
L
Site 3
Y38
P
R
T
W
R
N
N
Y
R
L
A
Q
A
Y
L
Site 4
Y44
N
Y
R
L
A
Q
A
Y
L
D
K
Y
Y
T
N
Site 5
Y48
A
Q
A
Y
L
D
K
Y
Y
T
N
K
E
G
H
Site 6
Y49
Q
A
Y
L
D
K
Y
Y
T
N
K
E
G
H
Q
Site 7
S65
G
E
M
V
A
R
G
S
N
S
M
I
R
K
I
Site 8
T90
V
T
G
K
L
D
Q
T
T
M
N
V
I
K
K
Site 9
T91
T
G
K
L
D
Q
T
T
M
N
V
I
K
K
P
Site 10
T123
K
W
K
K
N
T
L
T
Y
R
I
S
K
Y
T
Site 11
Y124
W
K
K
N
T
L
T
Y
R
I
S
K
Y
T
P
Site 12
S127
N
T
L
T
Y
R
I
S
K
Y
T
P
S
M
S
Site 13
Y129
L
T
Y
R
I
S
K
Y
T
P
S
M
S
S
V
Site 14
T130
T
Y
R
I
S
K
Y
T
P
S
M
S
S
V
E
Site 15
S132
R
I
S
K
Y
T
P
S
M
S
S
V
E
V
D
Site 16
S134
S
K
Y
T
P
S
M
S
S
V
E
V
D
K
A
Site 17
S170
G
E
A
D
I
M
I
S
F
E
N
G
D
H
G
Site 18
S179
E
N
G
D
H
G
D
S
Y
P
F
D
G
P
R
Site 19
Y180
N
G
D
H
G
D
S
Y
P
F
D
G
P
R
G
Site 20
T188
P
F
D
G
P
R
G
T
L
A
H
A
F
A
P
Site 21
S241
L
A
H
S
T
D
P
S
A
L
M
Y
P
T
Y
Site 22
Y245
T
D
P
S
A
L
M
Y
P
T
Y
K
Y
K
N
Site 23
Y248
S
A
L
M
Y
P
T
Y
K
Y
K
N
P
Y
G
Site 24
Y250
L
M
Y
P
T
Y
K
Y
K
N
P
Y
G
F
H
Site 25
Y254
T
Y
K
Y
K
N
P
Y
G
F
H
L
P
K
D
Site 26
T281
K
V
F
L
G
K
P
T
L
P
H
A
P
H
H
Site 27
S291
H
A
P
H
H
K
P
S
I
P
D
L
C
D
S
Site 28
S298
S
I
P
D
L
C
D
S
S
S
S
F
D
A
V
Site 29
S299
I
P
D
L
C
D
S
S
S
S
F
D
A
V
T
Site 30
S300
P
D
L
C
D
S
S
S
S
F
D
A
V
T
M
Site 31
S334
L
R
T
G
I
R
P
S
T
I
T
S
S
F
P
Site 32
T335
R
T
G
I
R
P
S
T
I
T
S
S
F
P
Q
Site 33
T337
G
I
R
P
S
T
I
T
S
S
F
P
Q
L
M
Site 34
S338
I
R
P
S
T
I
T
S
S
F
P
Q
L
M
S
Site 35
S339
R
P
S
T
I
T
S
S
F
P
Q
L
M
S
N
Site 36
S345
S
S
F
P
Q
L
M
S
N
V
D
A
A
Y
E
Site 37
Y351
M
S
N
V
D
A
A
Y
E
V
A
E
R
G
T
Site 38
T358
Y
E
V
A
E
R
G
T
A
Y
F
F
K
G
P
Site 39
Y360
V
A
E
R
G
T
A
Y
F
F
K
G
P
H
Y
Site 40
T381
Q
M
Q
G
P
P
R
T
I
Y
D
F
G
F
P
Site 41
Y383
Q
G
P
P
R
T
I
Y
D
F
G
F
P
R
H
Site 42
Y399
Q
Q
I
D
A
A
V
Y
L
R
E
P
Q
K
T
Site 43
T406
Y
L
R
E
P
Q
K
T
L
F
F
V
G
D
E
Site 44
Y414
L
F
F
V
G
D
E
Y
Y
S
Y
D
E
R
K
Site 45
Y415
F
F
V
G
D
E
Y
Y
S
Y
D
E
R
K
R
Site 46
S416
F
V
G
D
E
Y
Y
S
Y
D
E
R
K
R
K
Site 47
Y417
V
G
D
E
Y
Y
S
Y
D
E
R
K
R
K
M
Site 48
Y428
K
R
K
M
E
K
D
Y
P
K
N
T
E
E
E
Site 49
T432
E
K
D
Y
P
K
N
T
E
E
E
F
S
G
V
Site 50
S437
K
N
T
E
E
E
F
S
G
V
N
G
Q
I
D
Site 51
Y454
V
E
L
N
G
Y
I
Y
F
F
S
G
P
K
T
Site 52
T461
Y
F
F
S
G
P
K
T
Y
K
Y
D
T
E
K
Site 53
Y462
F
F
S
G
P
K
T
Y
K
Y
D
T
E
K
E
Site 54
Y464
S
G
P
K
T
Y
K
Y
D
T
E
K
E
D
V
Site 55
T466
P
K
T
Y
K
Y
D
T
E
K
E
D
V
V
S
Site 56
S473
T
E
K
E
D
V
V
S
V
V
K
S
S
S
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation