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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBL1X
Full Name:
F-box-like/WD repeat-containing protein TBL1X
Alias:
EBI; F-box-like/WD-repeat protein TBL1X; SMAP55; TBL1; TBLX; transducin (beta)-like 1X-linked; transducin beta-like 1X protein; transducin-beta-like 1, X-linked
Type:
Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Mass (Da):
62496
Number AA:
577
UniProt ID:
O60907
International Prot ID:
IPI00218132
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005876
GO:0017053
Uniprot
OncoNet
Molecular Function:
GO:0008013
GO:0042393
GO:0010843
PhosphoSite+
KinaseNET
Biological Process:
GO:0060070
GO:0010553
GO:0045944
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
E
L
A
G
A
S
S
S
C
C
H
R
P
A
Site 2
S10
E
L
A
G
A
S
S
S
C
C
H
R
P
A
G
Site 3
S23
A
G
R
G
A
M
Q
S
V
L
H
H
F
Q
R
Site 4
S38
L
R
G
R
E
G
G
S
H
F
I
N
T
S
S
Site 5
T43
G
G
S
H
F
I
N
T
S
S
P
R
G
E
A
Site 6
S45
S
H
F
I
N
T
S
S
P
R
G
E
A
K
M
Site 7
S53
P
R
G
E
A
K
M
S
I
T
S
D
E
V
N
Site 8
Y66
V
N
F
L
V
Y
R
Y
L
Q
E
S
G
F
S
Site 9
S70
V
Y
R
Y
L
Q
E
S
G
F
S
H
S
A
F
Site 10
S73
Y
L
Q
E
S
G
F
S
H
S
A
F
T
F
G
Site 11
S75
Q
E
S
G
F
S
H
S
A
F
T
F
G
I
E
Site 12
S86
F
G
I
E
S
H
I
S
Q
S
N
I
N
G
T
Site 13
S88
I
E
S
H
I
S
Q
S
N
I
N
G
T
L
V
Site 14
S116
Q
Y
V
E
A
E
I
S
I
N
E
D
G
T
V
Site 15
T122
I
S
I
N
E
D
G
T
V
F
D
G
R
P
I
Site 16
S179
A
T
A
A
T
T
T
S
A
G
V
S
H
Q
N
Site 17
S183
T
T
T
S
A
G
V
S
H
Q
N
P
S
K
N
Site 18
S188
G
V
S
H
Q
N
P
S
K
N
R
E
A
T
V
Site 19
T194
P
S
K
N
R
E
A
T
V
N
G
E
E
N
R
Site 20
S204
G
E
E
N
R
A
H
S
V
N
N
H
A
K
P
Site 21
S223
G
E
V
E
I
P
S
S
K
A
T
V
L
R
G
Site 22
T226
E
I
P
S
S
K
A
T
V
L
R
G
H
E
S
Site 23
S249
P
V
S
D
L
L
A
S
G
S
G
D
S
T
A
Site 24
S251
S
D
L
L
A
S
G
S
G
D
S
T
A
R
I
Site 25
S254
L
A
S
G
S
G
D
S
T
A
R
I
W
N
L
Site 26
T255
A
S
G
S
G
D
S
T
A
R
I
W
N
L
N
Site 27
S269
N
E
N
S
N
G
G
S
T
Q
L
V
L
R
H
Site 28
S287
E
G
G
H
D
V
P
S
N
K
D
V
T
S
L
Site 29
S293
P
S
N
K
D
V
T
S
L
D
W
N
T
N
G
Site 30
T301
L
D
W
N
T
N
G
T
L
L
A
T
G
S
Y
Site 31
T316
D
G
F
A
R
I
W
T
E
D
G
N
L
A
S
Site 32
S346
R
K
G
N
Y
I
L
S
A
G
V
D
K
T
T
Site 33
T353
S
A
G
V
D
K
T
T
I
I
W
D
A
H
T
Site 34
T383
D
V
D
W
Q
N
N
T
T
F
A
S
C
S
T
Site 35
T407
G
C
D
R
P
V
K
T
F
Q
G
H
T
N
E
Site 36
Y458
Q
A
H
N
K
E
I
Y
T
I
K
W
S
P
T
Site 37
T459
A
H
N
K
E
I
Y
T
I
K
W
S
P
T
G
Site 38
S463
E
I
Y
T
I
K
W
S
P
T
G
P
A
T
S
Site 39
T469
W
S
P
T
G
P
A
T
S
N
P
N
S
N
I
Site 40
S470
S
P
T
G
P
A
T
S
N
P
N
S
N
I
M
Site 41
S474
P
A
T
S
N
P
N
S
N
I
M
L
A
S
A
Site 42
T486
A
S
A
S
F
D
S
T
V
R
L
W
D
I
E
Site 43
T500
E
R
G
V
C
T
H
T
L
T
K
H
Q
E
P
Site 44
T502
G
V
C
T
H
T
L
T
K
H
Q
E
P
V
Y
Site 45
Y509
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Site 46
S510
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
G
Site 47
Y519
A
F
S
P
D
G
K
Y
L
A
S
G
S
F
D
Site 48
S524
G
K
Y
L
A
S
G
S
F
D
K
C
V
H
I
Site 49
S542
Q
S
G
N
L
V
H
S
Y
R
G
T
G
G
I
Site 50
Y543
S
G
N
L
V
H
S
Y
R
G
T
G
G
I
F
Site 51
S564
R
G
D
K
V
G
A
S
A
S
D
G
S
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation