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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNaseH1
Full Name:
Ribonuclease H1
Alias:
H1RNA; Ribonuclease H type II; RNase H1; RNH1
Type:
Ribonuclease; Mitochondrial; RNA binding protein; EC 3.1.26.4
Mass (Da):
32064
Number AA:
286
UniProt ID:
O60930
International Prot ID:
IPI00000077
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000287
GO:0004523
PhosphoSite+
KinaseNET
Biological Process:
GO:0006401
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
A
L
P
C
R
R
G
S
R
G
F
G
M
F
Y
Site 2
Y29
S
R
G
F
G
M
F
Y
A
V
R
R
G
R
K
Site 3
T37
A
V
R
R
G
R
K
T
G
V
F
L
T
W
N
Site 4
S74
A
W
A
F
V
R
K
S
A
S
P
E
V
S
E
Site 5
S76
A
F
V
R
K
S
A
S
P
E
V
S
E
G
H
Site 6
S80
K
S
A
S
P
E
V
S
E
G
H
E
N
Q
H
Site 7
S96
Q
E
S
E
A
K
A
S
K
R
L
R
E
P
L
Site 8
Y114
G
H
E
S
A
E
P
Y
A
K
H
M
K
P
S
Site 9
S121
Y
A
K
H
M
K
P
S
V
E
P
A
P
P
V
Site 10
S129
V
E
P
A
P
P
V
S
R
D
T
F
S
Y
M
Site 11
T132
A
P
P
V
S
R
D
T
F
S
Y
M
G
D
F
Site 12
S150
Y
T
D
G
C
C
S
S
N
G
R
R
R
P
R
Site 13
Y163
P
R
A
G
I
G
V
Y
W
G
P
G
H
P
L
Site 14
T181
I
R
L
P
G
R
Q
T
N
Q
R
A
E
I
H
Site 15
T199
K
A
I
E
Q
A
K
T
Q
N
I
N
K
L
V
Site 16
S233
K
K
N
G
W
K
T
S
A
G
K
E
V
I
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation