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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARC
Full Name:
Nucleolar protein 3
Alias:
Apoptosis repressor ARC; Apoptosis repressor with CARD; Apoptosis repressor with CARD domain; Apoptosis repressor with caspase recruitment domain (CARD); CARD2; Muscle-enriched cytoplasmic protein; Myp; NOL3; Nop30; Nucleolar protein of 30 kDa
Type:
Apoptosis
Mass (Da):
24309
Number AA:
219
UniProt ID:
O60936
International Prot ID:
IPI00105916
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006916
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
G
N
A
Q
E
R
P
S
E
T
I
D
R
E
R
Site 2
T109
M
T
L
H
A
Q
A
T
G
R
R
R
H
P
A
Site 3
T129
P
G
C
P
E
L
Q
T
L
T
R
P
G
A
L
Site 4
S149
C
N
P
G
P
R
R
S
Q
S
Q
S
W
K
L
Site 5
S151
P
G
P
R
R
S
Q
S
Q
S
W
K
L
R
P
Site 6
S153
P
R
R
S
Q
S
Q
S
W
K
L
R
P
L
K
Site 7
S165
P
L
K
R
L
N
R
S
R
S
Q
S
Q
S
W
Site 8
S167
K
R
L
N
R
S
R
S
Q
S
Q
S
W
N
P
Site 9
S169
L
N
R
S
R
S
Q
S
Q
S
W
N
P
R
L
Site 10
S171
R
S
R
S
Q
S
Q
S
W
N
P
R
L
K
Q
Site 11
S181
P
R
L
K
Q
N
Q
S
R
N
W
S
Q
N
R
Site 12
S185
Q
N
Q
S
R
N
W
S
Q
N
R
T
Q
S
P
Site 13
T189
R
N
W
S
Q
N
R
T
Q
S
P
S
P
T
S
Site 14
S191
W
S
Q
N
R
T
Q
S
P
S
P
T
S
R
K
Site 15
S193
Q
N
R
T
Q
S
P
S
P
T
S
R
K
G
T
Site 16
T195
R
T
Q
S
P
S
P
T
S
R
K
G
T
S
P
Site 17
S196
T
Q
S
P
S
P
T
S
R
K
G
T
S
P
K
Site 18
T200
S
P
T
S
R
K
G
T
S
P
K
I
P
E
G
Site 19
S201
P
T
S
R
K
G
T
S
P
K
I
P
E
G
Q
Site 20
S209
P
K
I
P
E
G
Q
S
S
D
R
R
C
P
A
Site 21
S210
K
I
P
E
G
Q
S
S
D
R
R
C
P
A
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation