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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCB7
Full Name:
ATP-binding cassette sub-family B member 7, mitochondrial
Alias:
ABC transporter 7 protein; ABC7; Anemia, sideroblastic, with spinocerebellar ataxia; ASAT; Atm1p; ATP-binding cassette, sub-family B (MDR/TAP), member 7
Type:
Transporter
Mass (Da):
82641
Number AA:
752
UniProt ID:
O75027
International Prot ID:
IPI00306748
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005743
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042626
GO:0015232
PhosphoSite+
KinaseNET
Biological Process:
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
A
F
E
K
R
R
H
S
A
I
L
I
R
P
L
Site 2
S35
I
R
P
L
V
S
V
S
G
S
G
P
Q
W
R
Site 3
S37
P
L
V
S
V
S
G
S
G
P
Q
W
R
P
H
Site 4
T51
H
Q
L
G
A
L
G
T
A
R
A
Y
Q
I
P
Site 5
Y55
A
L
G
T
A
R
A
Y
Q
I
P
E
S
L
K
Site 6
S60
R
A
Y
Q
I
P
E
S
L
K
S
I
T
W
Q
Site 7
S63
Q
I
P
E
S
L
K
S
I
T
W
Q
R
L
G
Site 8
T65
P
E
S
L
K
S
I
T
W
Q
R
L
G
K
G
Site 9
S74
Q
R
L
G
K
G
N
S
G
Q
F
L
D
A
A
Site 10
T117
E
G
L
K
D
V
D
T
R
K
I
I
K
A
M
Site 11
Y127
I
I
K
A
M
L
S
Y
V
W
P
K
D
R
P
Site 12
S179
S
G
N
M
L
N
L
S
D
A
P
N
T
V
A
Site 13
Y196
A
T
A
V
L
I
G
Y
G
V
S
R
A
G
A
Site 14
S199
V
L
I
G
Y
G
V
S
R
A
G
A
A
F
F
Site 15
S221
F
G
K
V
A
Q
N
S
I
R
R
I
A
K
N
Site 16
S243
L
D
L
G
F
H
L
S
R
Q
T
G
A
L
S
Site 17
T246
G
F
H
L
S
R
Q
T
G
A
L
S
K
A
I
Site 18
S250
S
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
Site 19
T257
S
K
A
I
D
R
G
T
R
G
I
S
F
V
L
Site 20
S261
D
R
G
T
R
G
I
S
F
V
L
S
A
L
V
Site 21
S265
R
G
I
S
F
V
L
S
A
L
V
F
N
L
L
Site 22
Y340
A
I
D
S
L
L
N
Y
E
T
V
K
Y
F
N
Site 23
T342
D
S
L
L
N
Y
E
T
V
K
Y
F
N
N
E
Site 24
Y345
L
N
Y
E
T
V
K
Y
F
N
N
E
R
Y
E
Site 25
Y351
K
Y
F
N
N
E
R
Y
E
A
Q
R
Y
D
G
Site 26
Y356
E
R
Y
E
A
Q
R
Y
D
G
F
L
K
T
Y
Site 27
T362
R
Y
D
G
F
L
K
T
Y
E
T
A
S
L
K
Site 28
Y363
Y
D
G
F
L
K
T
Y
E
T
A
S
L
K
S
Site 29
T365
G
F
L
K
T
Y
E
T
A
S
L
K
S
T
S
Site 30
S367
L
K
T
Y
E
T
A
S
L
K
S
T
S
T
L
Site 31
S370
Y
E
T
A
S
L
K
S
T
S
T
L
A
M
L
Site 32
T371
E
T
A
S
L
K
S
T
S
T
L
A
M
L
N
Site 33
T429
L
P
L
N
F
L
G
T
V
Y
R
E
T
R
Q
Site 34
T434
L
G
T
V
Y
R
E
T
R
Q
A
L
I
D
M
Site 35
T446
I
D
M
N
T
L
F
T
L
L
K
V
D
T
Q
Site 36
S461
I
K
D
K
V
M
A
S
P
L
Q
I
T
P
Q
Site 37
S489
I
E
G
Q
K
V
L
S
G
I
S
F
E
V
P
Site 38
S492
Q
K
V
L
S
G
I
S
F
E
V
P
A
G
K
Site 39
T513
G
S
G
S
G
K
S
T
I
V
R
L
L
F
R
Site 40
Y522
V
R
L
L
F
R
F
Y
E
P
Q
K
G
S
I
Site 41
Y530
E
P
Q
K
G
S
I
Y
L
A
G
Q
N
I
Q
Site 42
S540
G
Q
N
I
Q
D
V
S
L
E
S
L
R
R
A
Site 43
S572
N
L
L
Y
G
N
I
S
A
S
P
E
E
V
Y
Site 44
Y598
I
L
R
M
P
H
G
Y
D
T
Q
V
G
E
R
Site 45
T600
R
M
P
H
G
Y
D
T
Q
V
G
E
R
G
L
Site 46
S610
G
E
R
G
L
K
L
S
G
G
E
K
Q
R
V
Site 47
Y632
K
D
P
P
V
I
L
Y
D
E
A
T
S
S
L
Site 48
S638
L
Y
D
E
A
T
S
S
L
D
S
I
T
E
E
Site 49
S641
E
A
T
S
S
L
D
S
I
T
E
E
T
I
L
Site 50
S660
D
V
V
K
H
R
T
S
I
F
I
A
H
R
L
Site 51
T689
G
K
V
A
E
R
G
T
H
H
G
L
L
A
N
Site 52
T707
I
Y
S
E
M
W
H
T
Q
S
S
R
V
Q
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation