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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLXNA2
Full Name:
Plexin-A2
Alias:
FLJ11751; FLJ30634; KIAA0463; OCT; plexin 2; plexin A2; plexin-A2; PLXA2; PLXN2; semaphorin receptor OCT; transmembrane protein OCT
Type:
Membrane protein, integral; Receptor, misc.
Mass (Da):
212655
Number AA:
1963
UniProt ID:
O75051
International Prot ID:
IPI00719621
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
GO:0005886
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y293
D
D
P
K
F
H
S
Y
V
S
L
P
F
G
C
Site 2
S295
P
K
F
H
S
Y
V
S
L
P
F
G
C
T
R
Site 3
S434
T
S
R
D
R
M
T
S
V
A
S
Y
V
Y
N
Site 4
S444
S
Y
V
Y
N
G
Y
S
V
V
F
V
G
T
K
Site 5
Y470
P
P
H
G
G
V
Q
Y
E
M
V
S
V
L
K
Site 6
S474
G
V
Q
Y
E
M
V
S
V
L
K
D
G
S
P
Site 7
S850
S
P
W
L
D
W
S
S
H
N
V
K
C
S
N
Site 8
S1264
L
I
A
Y
K
R
K
S
R
E
N
D
L
T
L
Site 9
T1270
K
S
R
E
N
D
L
T
L
K
R
L
Q
M
Q
Site 10
S1310
L
T
S
D
L
D
R
S
G
I
P
Y
L
D
Y
Site 11
Y1314
L
D
R
S
G
I
P
Y
L
D
Y
R
T
Y
A
Site 12
Y1317
S
G
I
P
Y
L
D
Y
R
T
Y
A
M
R
V
Site 13
Y1320
P
Y
L
D
Y
R
T
Y
A
M
R
V
L
F
P
Site 14
S1377
R
T
L
E
L
Q
R
S
F
S
M
R
D
R
G
Site 15
S1379
L
E
L
Q
R
S
F
S
M
R
D
R
G
N
V
Site 16
S1388
R
D
R
G
N
V
A
S
L
I
M
T
G
L
Q
Site 17
Y1400
G
L
Q
G
R
L
E
Y
A
T
D
V
L
K
Q
Site 18
T1402
Q
G
R
L
E
Y
A
T
D
V
L
K
Q
L
L
Site 19
T1430
P
K
L
L
L
R
R
T
E
S
V
A
E
K
M
Site 20
S1432
L
L
L
R
R
T
E
S
V
A
E
K
M
L
T
Site 21
T1478
K
G
P
I
D
A
I
T
G
E
A
R
Y
S
L
Site 22
S1484
I
T
G
E
A
R
Y
S
L
S
E
D
K
L
I
Site 23
S1486
G
E
A
R
Y
S
L
S
E
D
K
L
I
R
Q
Site 24
S1512
V
N
P
D
N
E
N
S
P
E
I
P
V
K
V
Site 25
Y1537
E
K
I
L
D
A
V
Y
K
N
V
P
Y
S
Q
Site 26
S1543
V
Y
K
N
V
P
Y
S
Q
R
P
R
A
V
D
Site 27
T1571
V
L
Q
D
E
D
I
T
T
K
I
E
G
D
W
Site 28
T1572
L
Q
D
E
D
I
T
T
K
I
E
G
D
W
K
Site 29
Y1587
R
L
N
T
L
M
H
Y
Q
V
S
D
R
S
V
Site 30
S1593
H
Y
Q
V
S
D
R
S
V
V
A
L
V
P
K
Site 31
S1604
L
V
P
K
Q
T
S
S
Y
N
I
P
A
S
A
Site 32
Y1605
V
P
K
Q
T
S
S
Y
N
I
P
A
S
A
S
Site 33
S1610
S
S
Y
N
I
P
A
S
A
S
I
S
R
T
S
Site 34
S1612
Y
N
I
P
A
S
A
S
I
S
R
T
S
I
S
Site 35
S1614
I
P
A
S
A
S
I
S
R
T
S
I
S
R
Y
Site 36
T1616
A
S
A
S
I
S
R
T
S
I
S
R
Y
D
S
Site 37
S1617
S
A
S
I
S
R
T
S
I
S
R
Y
D
S
S
Site 38
S1619
S
I
S
R
T
S
I
S
R
Y
D
S
S
F
R
Site 39
Y1621
S
R
T
S
I
S
R
Y
D
S
S
F
R
Y
T
Site 40
S1623
T
S
I
S
R
Y
D
S
S
F
R
Y
T
G
S
Site 41
S1624
S
I
S
R
Y
D
S
S
F
R
Y
T
G
S
P
Site 42
Y1627
R
Y
D
S
S
F
R
Y
T
G
S
P
D
S
L
Site 43
T1628
Y
D
S
S
F
R
Y
T
G
S
P
D
S
L
R
Site 44
S1630
S
S
F
R
Y
T
G
S
P
D
S
L
R
S
R
Site 45
S1633
R
Y
T
G
S
P
D
S
L
R
S
R
A
P
M
Site 46
S1636
G
S
P
D
S
L
R
S
R
A
P
M
I
T
P
Site 47
T1642
R
S
R
A
P
M
I
T
P
D
L
E
S
G
V
Site 48
S1670
Q
K
E
G
D
R
G
S
K
M
V
S
E
I
Y
Site 49
S1674
D
R
G
S
K
M
V
S
E
I
Y
L
T
R
L
Site 50
T1687
R
L
L
A
T
K
G
T
L
Q
K
F
V
D
D
Site 51
S1701
D
L
F
E
T
L
F
S
T
V
H
R
G
S
A
Site 52
S1728
D
E
Q
A
D
R
H
S
I
H
D
T
D
V
R
Site 53
S1781
V
A
Q
T
F
M
D
S
C
S
T
S
E
H
R
Site 54
S1783
Q
T
F
M
D
S
C
S
T
S
E
H
R
L
G
Site 55
S1785
F
M
D
S
C
S
T
S
E
H
R
L
G
K
D
Site 56
S1793
E
H
R
L
G
K
D
S
P
S
N
K
L
L
Y
Site 57
S1795
R
L
G
K
D
S
P
S
N
K
L
L
Y
A
K
Site 58
Y1800
S
P
S
N
K
L
L
Y
A
K
D
I
P
S
Y
Site 59
S1806
L
Y
A
K
D
I
P
S
Y
K
S
W
V
E
R
Site 60
Y1807
Y
A
K
D
I
P
S
Y
K
S
W
V
E
R
Y
Site 61
Y1815
K
S
W
V
E
R
Y
Y
A
D
I
A
K
L
P
Site 62
S1825
I
A
K
L
P
A
I
S
D
Q
D
M
N
A
Y
Site 63
Y1832
S
D
Q
D
M
N
A
Y
L
A
E
Q
S
R
L
Site 64
Y1854
L
S
A
L
N
E
I
Y
S
Y
V
S
K
Y
S
Site 65
S1855
S
A
L
N
E
I
Y
S
Y
V
S
K
Y
S
E
Site 66
Y1856
A
L
N
E
I
Y
S
Y
V
S
K
Y
S
E
E
Site 67
Y1860
I
Y
S
Y
V
S
K
Y
S
E
E
L
I
G
A
Site 68
S1861
Y
S
Y
V
S
K
Y
S
E
E
L
I
G
A
L
Site 69
Y1881
A
R
R
Q
R
L
A
Y
K
V
E
Q
L
I
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation