PhosphoNET

           
Protein Info 
   
Short Name:  LRP3
Full Name:  Low-density lipoprotein receptor-related protein 3
Alias:  105 kDa low-density lipoprotein receptor-related protein
Type: 
Mass (Da):  82884
Number AA:  770
UniProt ID:  O75074
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y58TERRGVIYSPAWPLN
Site 2Y66SPAWPLNYPPGTNCS
Site 3Y75PGTNCSWYIQGDRGD
Site 4Y523LGCAFKLYSLRTQEY
Site 5S524GCAFKLYSLRTQEYR
Site 6T538RAFETQMTRLEAEFV
Site 7S552VRREAPPSYGQLIAQ
Site 8Y553RREAPPSYGQLIAQG
Site 9Y571PVEDFPVYSASQASV
Site 10S574DFPVYSASQASVLQN
Site 11T584SVLQNLRTAMRRQMR
Site 12S595RQMRRHASRRGPSRR
Site 13S600HASRRGPSRRRLGRL
Site 14T626RGQIPLLTAARPSQT
Site 15S631LLTAARPSQTVLGDG
Site 16T657PPAPLMDTGSTRAAG
Site 17S659APLMDTGSTRAAGDR
Site 18S669AAGDRPPSAPGRAPE
Site 19S680RAPEVGPSGPPLPSG
Site 20S686PSGPPLPSGLRDPEC
Site 21S722DAPREPCSAQDPHPQ
Site 22S731QDPHPQVSTASSTLG
Site 23S734HPQVSTASSTLGPHS
Site 24S735PQVSTASSTLGPHSP
Site 25T736QVSTASSTLGPHSPE
Site 26S741SSTLGPHSPEPLGVC
Site 27S756RNPPPPCSPMLEASD
Site 28S762CSPMLEASDDEALLV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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