PhosphoNET

           
Protein Info 
   
Short Name:  WDR1
Full Name:  WD repeat-containing protein 1
Alias:  WD repeat-containing protein 1
Type: 
Mass (Da):  66176
Number AA:  606
UniProt ID:  O75083
International Prot ID:  IPI00873622
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005856  GO:0043226 Uniprot OncoNet
Molecular Function:  GO:0003779  GO:0005488  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0003008  GO:0007600  GO:0007605 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11EIKKVFASLPQVERG
Site 2S20PQVERGVSKIIGGDP
Site 3Y34PKGNNFLYTNGKCVI
Site 4Y54NPALADIYTEHAHQV
Site 5Y72KYAPSGFYIASGDVS
Site 6S79YIASGDVSGKLRIWD
Site 7T87GKLRIWDTTQKEHLL
Site 8T88KLRIWDTTQKEHLLK
Site 9Y96QKEHLLKYEYQPFAG
Site 10Y98EHLLKYEYQPFAGKI
Site 11S114DIAWTEDSKRIAVVG
Site 12S138FLWDSGSSVGEITGH
Site 13Y160DIKQSRPYRLATGSD
Site 14T164SRPYRLATGSDDNCA
Site 15S166PYRLATGSDDNCAAF
Site 16T184PPFKFKFTIGDHSRF
Site 17S198FVNCVRFSPDGNRFA
Site 18T206PDGNRFATASADGQI
Site 19S208GNRFATASADGQIYI
Site 20Y214ASADGQIYIYDGKTG
Site 21Y216ADGQIYIYDGKTGEK
Site 22Y238KAHDGGIYAISWSPD
Site 23S241DGGIYAISWSPDSTH
Site 24S246AISWSPDSTHLLSAS
Site 25T247ISWSPDSTHLLSASG
Site 26S251PDSTHLLSASGDKTS
Site 27S253STHLLSASGDKTSKI
Site 28T257LSASGDKTSKIWDVS
Site 29S258SASGDKTSKIWDVSV
Site 30S294WQKDHLLSVSLSGYI
Site 31S296KDHLLSVSLSGYINY
Site 32Y300LSVSLSGYINYLDRN
Site 33Y303SLSGYINYLDRNNPS
Site 34T327SKSIQCLTVHKNGGK
Site 35S335VHKNGGKSYIYSGSH
Site 36Y336HKNGGKSYIYSGSHD
Site 37Y338NGGKSYIYSGSHDGH
Site 38S339GGKSYIYSGSHDGHI
Site 39Y348SHDGHINYWDSETGE
Site 40T353INYWDSETGENDSFA
Site 41S358SETGENDSFAGKGHT
Site 42T372TNQVSRMTVDESGQL
Site 43S376SRMTVDESGQLISCS
Site 44S381DESGQLISCSMDDTV
Site 45S383SGQLISCSMDDTVRY
Site 46T387ISCSMDDTVRYTSLM
Site 47Y390SMDDTVRYTSLMLRD
Site 48T391MDDTVRYTSLMLRDY
Site 49S392DDTVRYTSLMLRDYS
Site 50Y398TSLMLRDYSGQGVVK
Site 51S399SLMLRDYSGQGVVKL
Site 52Y472VDGNVRLYSILGTTL
Site 53S473DGNVRLYSILGTTLK
Site 54T477RLYSILGTTLKDEGK
Site 55T493LEAKGPVTDVAYSHD
Site 56Y522VFSVADGYSENNVFY
Site 57S562MVYVWTLSDPETRVK
Site 58T566WTLSDPETRVKIQDA
Site 59S580AHRLHHVSSLAWLDE
Site 60S581HRLHHVSSLAWLDEH
Site 61T589LAWLDEHTLVTTSHD
Site 62S594EHTLVTTSHDASVKE
Site 63S598VTTSHDASVKEWTIT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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