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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AOC2
Full Name:
Retina-specific copper amine oxidase
Alias:
Amine oxidase [copper-containing];Semicarbazide-sensitive amine oxidase
Type:
Mass (Da):
83673
Number AA:
756
UniProt ID:
O75106
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
L
L
T
S
P
G
G
S
S
Q
P
P
H
C
P
Site 2
S32
L
T
S
P
G
G
S
S
Q
P
P
H
C
P
S
Site 3
S39
S
Q
P
P
H
C
P
S
V
S
H
R
A
Q
P
Site 4
S41
P
P
H
C
P
S
V
S
H
R
A
Q
P
W
P
Site 5
S53
P
W
P
H
P
G
Q
S
Q
L
F
A
D
L
S
Site 6
S60
S
Q
L
F
A
D
L
S
R
E
E
L
T
A
V
Site 7
S88
D
A
A
Q
A
Q
P
S
D
N
C
I
F
S
V
Site 8
S94
P
S
D
N
C
I
F
S
V
E
L
Q
L
P
P
Site 9
S113
L
A
H
L
D
R
G
S
P
P
P
A
R
E
A
Site 10
S146
V
G
P
L
P
H
P
S
Y
M
R
D
V
T
V
Site 11
Y147
G
P
L
P
H
P
S
Y
M
R
D
V
T
V
E
Site 12
T152
P
S
Y
M
R
D
V
T
V
E
R
H
G
G
P
Site 13
Y162
R
H
G
G
P
L
P
Y
H
R
R
P
V
L
R
Site 14
S192
P
K
A
P
I
F
L
S
S
T
F
N
Y
N
G
Site 15
S193
K
A
P
I
F
L
S
S
T
F
N
Y
N
G
S
Site 16
T194
A
P
I
F
L
S
S
T
F
N
Y
N
G
S
T
Site 17
T208
T
L
A
A
V
H
A
T
P
R
G
L
R
S
G
Site 18
T219
L
R
S
G
D
R
A
T
W
M
A
L
Y
H
N
Site 19
S277
Q
L
E
R
E
F
K
S
G
R
L
E
V
V
R
Site 20
S294
L
P
P
P
N
G
A
S
S
L
R
S
R
N
S
Site 21
S295
P
P
P
N
G
A
S
S
L
R
S
R
N
S
P
Site 22
S298
N
G
A
S
S
L
R
S
R
N
S
P
G
P
L
Site 23
S301
S
S
L
R
S
R
N
S
P
G
P
L
P
P
L
Site 24
S311
P
L
P
P
L
Q
F
S
P
Q
G
S
Q
Y
S
Site 25
S315
L
Q
F
S
P
Q
G
S
Q
Y
S
V
Q
G
N
Site 26
Y317
F
S
P
Q
G
S
Q
Y
S
V
Q
G
N
L
V
Site 27
S318
S
P
Q
G
S
Q
Y
S
V
Q
G
N
L
V
V
Site 28
Y355
F
Q
G
E
R
I
A
Y
E
V
S
V
Q
E
C
Site 29
Y366
V
Q
E
C
V
S
I
Y
G
A
D
S
P
K
T
Site 30
S370
V
S
I
Y
G
A
D
S
P
K
T
M
L
T
R
Site 31
T373
Y
G
A
D
S
P
K
T
M
L
T
R
Y
L
D
Site 32
T376
D
S
P
K
T
M
L
T
R
Y
L
D
S
S
F
Site 33
Y378
P
K
T
M
L
T
R
Y
L
D
S
S
F
G
L
Site 34
S381
M
L
T
R
Y
L
D
S
S
F
G
L
G
R
N
Site 35
S382
L
T
R
Y
L
D
S
S
F
G
L
G
R
N
S
Site 36
S389
S
F
G
L
G
R
N
S
R
G
L
V
R
G
V
Site 37
Y440
P
L
R
R
H
H
N
Y
L
Q
N
H
F
Y
G
Site 38
Y446
N
Y
L
Q
N
H
F
Y
G
G
L
A
S
S
A
Site 39
Y467
S
S
V
G
N
Y
D
Y
I
W
D
F
V
L
Y
Site 40
Y474
Y
I
W
D
F
V
L
Y
P
N
G
A
L
E
G
Site 41
Y488
G
R
V
H
A
T
G
Y
I
N
T
A
F
L
K
Site 42
S574
K
E
D
L
T
A
F
S
L
G
S
P
L
P
R
Site 43
Y582
L
G
S
P
L
P
R
Y
L
Y
L
A
S
N
Q
Site 44
Y584
S
P
L
P
R
Y
L
Y
L
A
S
N
Q
T
N
Site 45
Y599
A
W
G
H
Q
R
G
Y
R
I
Q
I
H
S
P
Site 46
S605
G
Y
R
I
Q
I
H
S
P
L
G
I
H
I
P
Site 47
S615
G
I
H
I
P
L
E
S
D
M
E
R
A
L
S
Site 48
S622
S
D
M
E
R
A
L
S
W
G
R
Y
Q
L
V
Site 49
Y626
R
A
L
S
W
G
R
Y
Q
L
V
V
T
Q
R
Site 50
T631
G
R
Y
Q
L
V
V
T
Q
R
K
E
E
E
S
Site 51
S638
T
Q
R
K
E
E
E
S
Q
S
S
S
I
Y
H
Site 52
S640
R
K
E
E
E
S
Q
S
S
S
I
Y
H
Q
N
Site 53
S642
E
E
E
S
Q
S
S
S
I
Y
H
Q
N
D
I
Site 54
Y644
E
S
Q
S
S
S
I
Y
H
Q
N
D
I
W
T
Site 55
T690
H
A
E
D
I
P
N
T
V
T
L
G
N
R
V
Site 56
Y704
V
G
F
L
L
R
P
Y
N
F
F
D
E
D
P
Site 57
S712
N
F
F
D
E
D
P
S
I
F
S
P
G
S
V
Site 58
S715
D
E
D
P
S
I
F
S
P
G
S
V
Y
F
E
Site 59
S718
P
S
I
F
S
P
G
S
V
Y
F
E
K
G
Q
Site 60
Y720
I
F
S
P
G
S
V
Y
F
E
K
G
Q
D
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation