PhosphoNET

           
Protein Info 
   
Short Name:  LDB3
Full Name:  LIM domain-binding protein 3
Alias:  CYPHER; Cypher; KIAA0613; Ldb3z1; Ldb3z4; LIM domain binding 3; ORACLE; PDLIM6; PDZ and LIM domain 6; Protein cypher; ZASP; Z-band alternatively spliced PDZ-motif; Z-band alternatively spliced PDZ-motif protein
Type:  Cytoskeletal protein
Mass (Da):  77116
Number AA:  727
UniProt ID:  O75112
International Prot ID:  IPI00165263
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030018  GO:0005856  GO:0048471 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSYSVTLTG
Site 2T6__MSYSVTLTGPGPW
Site 3T28KDFNMPLTISRITPG
Site 4T33PLTISRITPGSKAAQ
Site 5S36ISRITPGSKAAQSQL
Site 6S41PGSKAAQSQLSQGDL
Site 7S44KAAQSQLSQGDLVVA
Site 8T59IDGVNTDTMTHLEAQ
Site 9S71EAQNKIKSASYNLSL
Site 10S73QNKIKSASYNLSLTL
Site 11Y74NKIKSASYNLSLTLQ
Site 12S77KSASYNLSLTLQKSK
Site 13T79ASYNLSLTLQKSKRP
Site 14S83LSLTLQKSKRPIPIS
Site 15S90SKRPIPISTTAPPVQ
Site 16T92RPIPISTTAPPVQTP
Site 17T98TTAPPVQTPLPVIPH
Site 18T113QKDPALDTNGSLVAP
Site 19S116PALDTNGSLVAPSPS
Site 20S121NGSLVAPSPSPEARA
Site 21S123SLVAPSPSPEARASP
Site 22S129PSPEARASPGTPGTP
Site 23T132EARASPGTPGTPELR
Site 24T135ASPGTPGTPELRPTF
Site 25T141GTPELRPTFSPAFSR
Site 26S143PELRPTFSPAFSRPS
Site 27S147PTFSPAFSRPSAFSS
Site 28S150SPAFSRPSAFSSLAE
Site 29S153FSRPSAFSSLAEASD
Site 30S154SRPSAFSSLAEASDP
Site 31S159FSSLAEASDPGPPRA
Site 32S167DPGPPRASLRAKTSP
Site 33T172RASLRAKTSPEGARD
Site 34S173ASLRAKTSPEGARDL
Site 35S189GPKALPGSSQPRQYN
Site 36S190PKALPGSSQPRQYNN
Site 37Y195GSSQPRQYNNPIGLY
Site 38T206IGLYSAETLREMAQM
Site 39Y214LREMAQMYQMSLRGK
Site 40S217MAQMYQMSLRGKASG
Site 41S223MSLRGKASGVGLPGG
Site 42S243DLAVDSASPVYQAVI
Site 43Y246VDSASPVYQAVIKSQ
Site 44S252VYQAVIKSQNKPEDE
Site 45S267ADEWARRSSNLQSRS
Site 46S268DEWARRSSNLQSRSF
Site 47S272RRSSNLQSRSFRILA
Site 48S274SSNLQSRSFRILAQM
Site 49T282FRILAQMTGTEFMQD
Site 50S298DEEALRRSSTPIEHA
Site 51S299EEALRRSSTPIEHAP
Site 52T300EALRRSSTPIEHAPV
Site 53S328AQPPAAASPSAASPP
Site 54S355ASTTAPASSPADSPR
Site 55S356STTAPASSPADSPRP
Site 56S360PASSPADSPRPQASS
Site 57S367SPRPQASSYSPAVAA
Site 58S369RPQASSYSPAVAASS
Site 59S375YSPAVAASSAPATHT
Site 60S376SPAVAASSAPATHTS
Site 61T380AASSAPATHTSYSEG
Site 62S383SAPATHTSYSEGPAA
Site 63S385PATHTSYSEGPAAPA
Site 64T399APKPRVVTTASIRPS
Site 65T400PKPRVVTTASIRPSV
Site 66S402PRVVTTASIRPSVYQ
Site 67S406TTASIRPSVYQPVPA
Site 68S414VYQPVPASTYSPSPG
Site 69T415YQPVPASTYSPSPGA
Site 70S417PVPASTYSPSPGANY
Site 71S419PASTYSPSPGANYSP
Site 72S425PSPGANYSPTPYTPS
Site 73T427PGANYSPTPYTPSPA
Site 74T430NYSPTPYTPSPAPAY
Site 75S432SPTPYTPSPAPAYTP
Site 76Y437TPSPAPAYTPSPAPA
Site 77T438PSPAPAYTPSPAPAY
Site 78S440PAPAYTPSPAPAYTP
Site 79Y445TPSPAPAYTPSPVPT
Site 80T446PSPAPAYTPSPVPTY
Site 81S448PAPAYTPSPVPTYTP
Site 82T452YTPSPVPTYTPSPAP
Site 83Y453TPSPVPTYTPSPAPA
Site 84T454PSPVPTYTPSPAPAY
Site 85S456PVPTYTPSPAPAYTP
Site 86Y461TPSPAPAYTPSPAPN
Site 87T462PSPAPAYTPSPAPNY
Site 88S464PAPAYTPSPAPNYNP
Site 89Y469TPSPAPNYNPAPSVA
Site 90S474PNYNPAPSVAYSGGP
Site 91S478PAPSVAYSGGPAEPA
Site 92S486GGPAEPASRPPWVTD
Site 93T492ASRPPWVTDDSFSQK
Site 94S495PPWVTDDSFSQKFAP
Site 95S497WVTDDSFSQKFAPGK
Site 96S505QKFAPGKSTTSISKQ
Site 97T506KFAPGKSTTSISKQT
Site 98S510GKSTTSISKQTLPRG
Site 99T513TTSISKQTLPRGGPA
Site 100Y521LPRGGPAYTPAGPQV
Site 101T522PRGGPAYTPAGPQVP
Site 102T535VPPLARGTVQRAERF
Site 103S545RAERFPASSRTPLCG
Site 104S546AERFPASSRTPLCGH
Site 105T548RFPASSRTPLCGHCN
Site 106Y579PEEFTCAYCKTSLAD
Site 107Y597VEEQNNVYCERCYEQ
Site 108Y602NVYCERCYEQFFAPL
Site 109Y656HMEDGEPYCEKDYIN
Site 110Y661EPYCEKDYINLFSTK
Site 111S666KDYINLFSTKCHGCD
Site 112T667DYINLFSTKCHGCDF
Site 113S711LEGQPFYSKKDRPLC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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