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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
N4BP1
Full Name:
NEDD4-binding protein 1
Alias:
Nedd4 binding protein 1
Type:
Unknown function
Mass (Da):
100379
Number AA:
896
UniProt ID:
O75113
International Prot ID:
IPI00005667
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S64
G
A
Q
E
A
E
H
S
A
K
E
Y
I
K
G
Site 2
Y68
A
E
H
S
A
K
E
Y
I
K
G
I
C
E
P
Site 3
Y83
E
L
E
E
R
E
C
Y
P
K
D
M
H
C
I
Site 4
S149
E
N
K
E
N
L
P
S
S
Q
K
E
S
E
V
Site 5
S150
N
K
E
N
L
P
S
S
Q
K
E
S
E
V
K
Site 6
S154
L
P
S
S
Q
K
E
S
E
V
K
R
E
F
K
Site 7
S210
E
V
I
E
M
R
D
S
Q
Q
T
E
F
T
Q
Site 8
S226
A
A
T
G
L
N
I
S
R
D
E
T
V
L
Q
Site 9
T230
L
N
I
S
R
D
E
T
V
L
Q
E
E
A
R
Site 10
T242
E
A
R
N
K
A
G
T
P
V
S
E
L
T
K
Site 11
S245
N
K
A
G
T
P
V
S
E
L
T
K
Q
M
D
Site 12
T253
E
L
T
K
Q
M
D
T
V
L
S
S
S
P
D
Site 13
S256
K
Q
M
D
T
V
L
S
S
S
P
D
V
L
F
Site 14
S257
Q
M
D
T
V
L
S
S
S
P
D
V
L
F
D
Site 15
S258
M
D
T
V
L
S
S
S
P
D
V
L
F
D
P
Site 16
T270
F
D
P
I
N
G
L
T
P
D
E
E
A
L
S
Site 17
S277
T
P
D
E
E
A
L
S
N
E
R
I
C
Q
K
Site 18
S288
I
C
Q
K
R
R
F
S
D
S
E
E
R
H
T
Site 19
S290
Q
K
R
R
F
S
D
S
E
E
R
H
T
K
K
Site 20
T295
S
D
S
E
E
R
H
T
K
K
Q
F
S
L
E
Site 21
S300
R
H
T
K
K
Q
F
S
L
E
N
V
Q
E
G
Site 22
S325
G
N
V
I
A
D
L
S
D
S
S
A
D
S
E
Site 23
S327
V
I
A
D
L
S
D
S
S
A
D
S
E
N
L
Site 24
S328
I
A
D
L
S
D
S
S
A
D
S
E
N
L
S
Site 25
S331
L
S
D
S
S
A
D
S
E
N
L
S
P
D
I
Site 26
S335
S
A
D
S
E
N
L
S
P
D
I
K
E
T
T
Site 27
Y347
E
T
T
E
E
M
E
Y
N
I
L
V
N
F
F
Site 28
S398
F
Q
E
D
R
E
F
S
A
G
T
V
Y
P
E
Site 29
T401
D
R
E
F
S
A
G
T
V
Y
P
E
T
N
K
Site 30
Y403
E
F
S
A
G
T
V
Y
P
E
T
N
K
T
K
Site 31
T406
A
G
T
V
Y
P
E
T
N
K
T
K
N
K
G
Site 32
T409
V
Y
P
E
T
N
K
T
K
N
K
G
V
Y
S
Site 33
Y415
K
T
K
N
K
G
V
Y
S
S
T
N
E
L
T
Site 34
S416
T
K
N
K
G
V
Y
S
S
T
N
E
L
T
T
Site 35
S417
K
N
K
G
V
Y
S
S
T
N
E
L
T
T
D
Site 36
T422
Y
S
S
T
N
E
L
T
T
D
S
T
P
K
K
Site 37
T426
N
E
L
T
T
D
S
T
P
K
K
T
Q
A
H
Site 38
S443
Q
N
M
V
E
K
F
S
Q
L
P
F
K
V
E
Site 39
T462
T
S
N
C
R
I
N
T
F
R
T
V
P
I
E
Site 40
Y481
V
W
G
S
N
Q
N
Y
I
C
N
T
D
P
E
Site 41
T489
I
C
N
T
D
P
E
T
D
G
L
S
P
S
V
Site 42
S493
D
P
E
T
D
G
L
S
P
S
V
A
S
P
S
Site 43
S495
E
T
D
G
L
S
P
S
V
A
S
P
S
P
K
Site 44
S498
G
L
S
P
S
V
A
S
P
S
P
K
E
V
N
Site 45
S500
S
P
S
V
A
S
P
S
P
K
E
V
N
F
V
Site 46
S508
P
K
E
V
N
F
V
S
R
G
A
S
S
H
Q
Site 47
S512
N
F
V
S
R
G
A
S
S
H
Q
P
R
V
P
Site 48
S513
F
V
S
R
G
A
S
S
H
Q
P
R
V
P
L
Site 49
S540
L
L
P
N
N
M
K
S
A
C
E
K
R
L
G
Site 50
S550
E
K
R
L
G
C
C
S
S
P
H
S
K
P
N
Site 51
S551
K
R
L
G
C
C
S
S
P
H
S
K
P
N
C
Site 52
S554
G
C
C
S
S
P
H
S
K
P
N
C
S
T
L
Site 53
S559
P
H
S
K
P
N
C
S
T
L
S
P
P
M
P
Site 54
T560
H
S
K
P
N
C
S
T
L
S
P
P
M
P
L
Site 55
S562
K
P
N
C
S
T
L
S
P
P
M
P
L
P
Q
Site 56
S573
P
L
P
Q
L
L
P
S
V
T
D
A
R
S
A
Site 57
T575
P
Q
L
L
P
S
V
T
D
A
R
S
A
G
P
Site 58
S579
P
S
V
T
D
A
R
S
A
G
P
S
D
H
I
Site 59
S583
D
A
R
S
A
G
P
S
D
H
I
D
S
S
V
Site 60
S589
P
S
D
H
I
D
S
S
V
T
G
V
Q
R
F
Site 61
T599
G
V
Q
R
F
R
D
T
L
K
I
P
Y
K
L
Site 62
T615
L
K
N
E
P
G
R
T
D
L
K
H
I
V
I
Site 63
T658
K
L
G
N
R
N
I
T
V
F
V
P
Q
W
R
Site 64
T673
T
R
R
D
P
N
V
T
E
Q
H
F
L
T
Q
Site 65
T679
V
T
E
Q
H
F
L
T
Q
L
Q
E
L
G
I
Site 66
S702
V
F
G
E
R
I
A
S
H
D
D
R
F
L
L
Site 67
S734
E
F
V
N
E
S
V
S
W
R
E
I
I
T
K
Site 68
S763
P
D
D
P
L
G
R
S
G
P
R
L
E
E
F
Site 69
S796
N
V
G
M
F
D
P
S
F
R
V
P
G
T
Q
Site 70
T802
P
S
F
R
V
P
G
T
Q
A
A
S
T
S
H
Site 71
S808
G
T
Q
A
A
S
T
S
H
Q
P
P
T
R
I
Site 72
S820
T
R
I
Q
G
A
P
S
S
H
W
L
P
Q
Q
Site 73
S821
R
I
Q
G
A
P
S
S
H
W
L
P
Q
Q
P
Site 74
S851
P
M
P
A
Q
R
S
S
A
E
T
N
E
L
R
Site 75
T854
A
Q
R
S
S
A
E
T
N
E
L
R
E
A
L
Site 76
S868
L
L
K
I
F
P
D
S
E
Q
R
L
K
I
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation