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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0678
Full Name:
DnaJ homolog subfamily C member 13
Alias:
DNAJC13; DNJCD; O75165
Type:
Chaperone protein
Mass (Da):
254420
Number AA:
1021
UniProt ID:
O75165
International Prot ID:
IPI00307259
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0031072
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
N
K
D
L
A
C
F
Y
T
T
K
H
S
W
R
Site 2
Y24
K
H
S
W
R
G
K
Y
K
R
V
F
S
V
G
Site 3
S29
G
K
Y
K
R
V
F
S
V
G
T
H
A
I
T
Site 4
T37
V
G
T
H
A
I
T
T
Y
N
P
N
T
L
E
Site 5
Y38
G
T
H
A
I
T
T
Y
N
P
N
T
L
E
V
Site 6
T42
I
T
T
Y
N
P
N
T
L
E
V
T
N
Q
W
Site 7
Y51
E
V
T
N
Q
W
P
Y
G
D
I
C
S
I
S
Site 8
S58
Y
G
D
I
C
S
I
S
P
V
G
K
G
Q
G
Site 9
T71
Q
G
T
E
F
N
L
T
F
R
K
G
S
G
K
Site 10
S76
N
L
T
F
R
K
G
S
G
K
K
S
E
T
L
Site 11
S80
R
K
G
S
G
K
K
S
E
T
L
K
F
S
T
Site 12
T82
G
S
G
K
K
S
E
T
L
K
F
S
T
E
H
Site 13
S86
K
S
E
T
L
K
F
S
T
E
H
R
T
E
L
Site 14
T95
E
H
R
T
E
L
L
T
E
A
L
R
F
R
T
Site 15
T102
T
E
A
L
R
F
R
T
D
F
S
E
G
K
I
Site 16
S105
L
R
F
R
T
D
F
S
E
G
K
I
T
G
R
Site 17
T110
D
F
S
E
G
K
I
T
G
R
R
Y
N
C
Y
Site 18
Y114
G
K
I
T
G
R
R
Y
N
C
Y
K
H
H
W
Site 19
Y117
T
G
R
R
Y
N
C
Y
K
H
H
W
S
D
S
Site 20
S124
Y
K
H
H
W
S
D
S
R
K
P
V
I
L
E
Site 21
T144
F
D
Q
I
N
P
A
T
N
R
V
L
C
S
Y
Site 22
Y151
T
N
R
V
L
C
S
Y
D
Y
R
N
I
E
G
Site 23
Y153
R
V
L
C
S
Y
D
Y
R
N
I
E
G
F
V
Site 24
S184
S
R
L
H
L
F
A
S
E
Q
R
E
E
I
I
Site 25
S193
Q
R
E
E
I
I
K
S
A
I
D
H
A
G
N
Site 26
Y201
A
I
D
H
A
G
N
Y
I
G
I
S
L
R
I
Site 27
S205
A
G
N
Y
I
G
I
S
L
R
I
R
K
E
P
Site 28
Y218
E
P
L
E
F
E
Q
Y
L
N
L
R
F
G
K
Site 29
Y226
L
N
L
R
F
G
K
Y
S
T
D
E
S
I
T
Site 30
S227
N
L
R
F
G
K
Y
S
T
D
E
S
I
T
S
Site 31
T228
L
R
F
G
K
Y
S
T
D
E
S
I
T
S
L
Site 32
S231
G
K
Y
S
T
D
E
S
I
T
S
L
A
E
F
Site 33
S244
E
F
V
V
Q
K
I
S
P
R
H
S
E
P
V
Site 34
S248
Q
K
I
S
P
R
H
S
E
P
V
K
R
V
L
Site 35
T269
L
V
E
R
D
P
A
T
Y
N
I
A
T
L
K
Site 36
Y270
V
E
R
D
P
A
T
Y
N
I
A
T
L
K
P
Site 37
Y306
I
K
G
Q
V
R
K
Y
S
S
T
E
R
D
S
Site 38
S307
K
G
Q
V
R
K
Y
S
S
T
E
R
D
S
L
Site 39
S308
G
Q
V
R
K
Y
S
S
T
E
R
D
S
L
L
Site 40
T309
Q
V
R
K
Y
S
S
T
E
R
D
S
L
L
A
Site 41
S313
Y
S
S
T
E
R
D
S
L
L
A
S
L
L
D
Site 42
S317
E
R
D
S
L
L
A
S
L
L
D
G
V
R
A
Site 43
T335
R
D
V
C
V
K
M
T
P
T
H
K
G
Q
R
Site 44
S347
G
Q
R
W
G
L
L
S
M
P
V
D
E
E
V
Site 45
S356
P
V
D
E
E
V
E
S
L
H
L
R
F
L
A
Site 46
T446
K
A
G
F
L
A
F
T
Q
L
P
K
F
R
E
Site 47
S466
V
V
K
A
L
K
R
S
N
N
G
I
I
H
A
Site 48
Y489
M
C
P
M
H
D
D
Y
D
L
R
Q
E
Q
L
Site 49
S500
Q
E
Q
L
N
K
A
S
L
L
S
S
K
K
F
Site 50
S503
L
N
K
A
S
L
L
S
S
K
K
F
L
E
N
Site 51
S504
N
K
A
S
L
L
S
S
K
K
F
L
E
N
L
Site 52
S517
N
L
L
E
K
F
N
S
H
V
D
H
G
T
G
Site 53
S544
F
A
L
C
A
P
Y
S
E
T
T
E
G
Q
Q
Site 54
T598
E
G
D
K
E
I
A
T
K
M
Q
E
L
A
L
Site 55
S606
K
M
Q
E
L
A
L
S
E
G
A
L
P
R
H
Site 56
S623
T
A
M
F
T
I
S
S
D
Q
R
M
L
T
N
Site 57
T629
S
S
D
Q
R
M
L
T
N
R
Q
L
S
R
H
Site 58
S634
M
L
T
N
R
Q
L
S
R
H
L
V
G
L
W
Site 59
T642
R
H
L
V
G
L
W
T
A
D
N
A
T
A
T
Site 60
S666
G
L
L
A
Y
L
E
S
S
D
L
V
P
E
K
Site 61
Y691
V
K
I
A
M
D
Q
Y
G
K
F
N
K
V
P
Site 62
Y762
E
A
N
W
D
L
F
Y
Y
R
F
G
Q
D
H
Site 63
T787
T
R
E
E
L
K
D
T
L
E
S
E
M
R
A
Site 64
Y818
H
H
E
F
E
V
K
Y
E
C
L
A
E
E
I
Site 65
Y830
E
E
I
K
I
G
D
Y
Y
L
R
L
L
L
E
Site 66
Y831
E
I
K
I
G
D
Y
Y
L
R
L
L
L
E
E
Site 67
S844
E
E
D
E
N
E
E
S
G
S
I
K
R
S
Y
Site 68
S846
D
E
N
E
E
S
G
S
I
K
R
S
Y
E
F
Site 69
S850
E
S
G
S
I
K
R
S
Y
E
F
F
N
E
L
Site 70
Y851
S
G
S
I
K
R
S
Y
E
F
F
N
E
L
Y
Site 71
Y858
Y
E
F
F
N
E
L
Y
H
R
F
L
L
T
P
Site 72
T864
L
Y
H
R
F
L
L
T
P
K
V
N
M
K
C
Site 73
T892
H
E
E
I
G
P
F
T
D
T
R
Y
I
I
G
Site 74
Y896
G
P
F
T
D
T
R
Y
I
I
G
M
L
E
R
Site 75
T905
I
G
M
L
E
R
C
T
D
K
L
E
R
D
R
Site 76
T944
R
I
L
V
D
L
L
T
L
A
H
L
H
V
S
Site 77
T954
H
L
H
V
S
R
A
T
V
P
L
Q
S
N
V
Site 78
S972
A
P
D
M
K
R
E
S
E
K
E
W
Y
F
G
Site 79
Y977
R
E
S
E
K
E
W
Y
F
G
N
A
D
K
E
Site 80
Y1057
M
L
I
T
M
C
G
Y
F
P
S
R
D
Q
D
Site 81
S1079
P
K
V
K
R
L
L
S
D
S
T
C
L
P
H
Site 82
T1082
K
R
L
L
S
D
S
T
C
L
P
H
I
I
Q
Site 83
Y1107
E
K
V
A
I
L
L
Y
H
I
M
Q
D
N
P
Site 84
Y1120
N
P
Q
L
P
R
L
Y
L
S
G
V
F
F
F
Site 85
Y1131
V
F
F
F
I
M
M
Y
T
G
S
N
V
L
P
Site 86
Y1145
P
V
A
R
F
L
K
Y
T
H
T
K
Q
A
F
Site 87
T1146
V
A
R
F
L
K
Y
T
H
T
K
Q
A
F
K
Site 88
T1148
R
F
L
K
Y
T
H
T
K
Q
A
F
K
S
E
Site 89
S1154
H
T
K
Q
A
F
K
S
E
E
T
K
G
Q
D
Site 90
Y1179
L
P
E
A
M
V
C
Y
L
E
N
Y
E
P
E
Site 91
T1198
I
F
L
G
E
F
D
T
P
E
A
I
W
S
S
Site 92
S1204
D
T
P
E
A
I
W
S
S
E
M
R
R
L
M
Site 93
S1205
T
P
E
A
I
W
S
S
E
M
R
R
L
M
I
Site 94
T1223
A
A
H
L
A
D
F
T
P
R
L
Q
S
N
T
Site 95
S1228
D
F
T
P
R
L
Q
S
N
T
R
A
L
Y
Q
Site 96
T1230
T
P
R
L
Q
S
N
T
R
A
L
Y
Q
Y
C
Site 97
Y1234
Q
S
N
T
R
A
L
Y
Q
Y
C
P
I
P
I
Site 98
Y1236
N
T
R
A
L
Y
Q
Y
C
P
I
P
I
I
N
Site 99
Y1244
C
P
I
P
I
I
N
Y
P
Q
L
E
N
E
L
Site 100
Y1256
N
E
L
F
C
N
I
Y
Y
L
K
Q
L
C
D
Site 101
T1264
Y
L
K
Q
L
C
D
T
L
R
F
P
D
W
P
Site 102
Y1303
M
M
S
I
D
D
A
Y
E
V
L
N
L
P
Q
Site 103
S1318
G
Q
G
P
H
D
E
S
K
I
R
K
A
Y
F
Site 104
Y1324
E
S
K
I
R
K
A
Y
F
R
L
A
Q
K
Y
Site 105
Y1331
Y
F
R
L
A
Q
K
Y
H
P
D
K
N
P
E
Site 106
T1355
K
A
Y
E
F
L
C
T
K
S
A
K
I
V
D
Site 107
Y1390
H
K
E
D
L
Q
P
Y
K
Y
A
G
Y
P
M
Site 108
Y1392
E
D
L
Q
P
Y
K
Y
A
G
Y
P
M
L
I
Site 109
Y1395
Q
P
Y
K
Y
A
G
Y
P
M
L
I
R
T
I
Site 110
T1401
G
Y
P
M
L
I
R
T
I
T
M
E
T
S
D
Site 111
T1403
P
M
L
I
R
T
I
T
M
E
T
S
D
D
L
Site 112
S1407
R
T
I
T
M
E
T
S
D
D
L
L
F
S
K
Site 113
S1413
T
S
D
D
L
L
F
S
K
E
S
P
L
L
P
Site 114
T1461
S
R
C
V
A
V
L
T
R
S
S
K
P
S
D
Site 115
S1463
C
V
A
V
L
T
R
S
S
K
P
S
D
M
S
Site 116
S1464
V
A
V
L
T
R
S
S
K
P
S
D
M
S
V
Site 117
S1467
L
T
R
S
S
K
P
S
D
M
S
V
Q
V
C
Site 118
S1470
S
S
K
P
S
D
M
S
V
Q
V
C
G
Y
I
Site 119
S1482
G
Y
I
S
K
C
Y
S
V
A
A
Q
F
E
E
Site 120
T1495
E
E
C
R
E
K
I
T
E
M
P
S
I
I
K
Site 121
Y1509
K
D
L
C
R
V
L
Y
F
G
K
S
I
P
R
Site 122
Y1556
G
F
L
F
N
Y
D
Y
T
L
E
E
S
G
I
Site 123
T1557
F
L
F
N
Y
D
Y
T
L
E
E
S
G
I
Q
Site 124
S1566
E
E
S
G
I
Q
K
S
E
E
T
N
Q
Q
E
Site 125
S1577
N
Q
Q
E
V
A
N
S
L
A
K
L
S
V
H
Site 126
T1599
Y
L
A
E
E
Q
A
T
P
E
N
P
T
I
R
Site 127
T1604
Q
A
T
P
E
N
P
T
I
R
K
S
L
A
G
Site 128
S1608
E
N
P
T
I
R
K
S
L
A
G
M
L
T
P
Site 129
Y1616
L
A
G
M
L
T
P
Y
V
A
R
K
L
A
V
Site 130
S1635
E
I
L
K
M
L
N
S
N
T
E
S
P
Y
L
Site 131
T1637
L
K
M
L
N
S
N
T
E
S
P
Y
L
I
W
Site 132
Y1641
N
S
N
T
E
S
P
Y
L
I
W
N
N
S
T
Site 133
S1647
P
Y
L
I
W
N
N
S
T
R
A
E
L
L
E
Site 134
S1658
E
L
L
E
F
L
E
S
Q
Q
E
N
M
I
K
Site 135
T1672
K
K
G
D
C
D
K
T
Y
G
S
E
F
V
Y
Site 136
Y1673
K
G
D
C
D
K
T
Y
G
S
E
F
V
Y
S
Site 137
Y1679
T
Y
G
S
E
F
V
Y
S
D
H
A
K
E
L
Site 138
S1680
Y
G
S
E
F
V
Y
S
D
H
A
K
E
L
I
Site 139
Y1696
G
E
I
F
V
R
V
Y
N
E
V
P
T
F
Q
Site 140
T1701
R
V
Y
N
E
V
P
T
F
Q
L
E
V
P
K
Site 141
S1720
S
L
L
D
Y
I
G
S
Q
A
Q
Y
L
H
T
Site 142
Y1762
A
L
R
N
V
I
K
Y
N
P
G
S
E
S
E
Site 143
S1766
V
I
K
Y
N
P
G
S
E
S
E
C
I
G
H
Site 144
S1768
K
Y
N
P
G
S
E
S
E
C
I
G
H
F
K
Site 145
S1842
E
T
L
Y
A
L
T
S
S
T
K
I
I
K
E
Site 146
S1843
T
L
Y
A
L
T
S
S
T
K
I
I
K
E
A
Site 147
T1875
H
P
Q
V
R
A
Q
T
A
E
L
F
A
K
M
Site 148
S1934
E
L
I
W
N
D
N
S
R
D
K
V
S
T
T
Site 149
S1939
D
N
S
R
D
K
V
S
T
T
V
R
E
M
M
Site 150
T1940
N
S
R
D
K
V
S
T
T
V
R
E
M
M
L
Site 151
T1941
S
R
D
K
V
S
T
T
V
R
E
M
M
L
E
Site 152
S2068
R
N
N
A
I
P
K
S
A
I
R
V
I
H
A
Site 153
T2105
G
M
K
K
R
A
D
T
V
G
L
A
C
E
A
Site 154
S2151
I
G
L
E
N
L
D
S
P
A
A
T
K
A
Q
Site 155
S2184
N
E
I
L
C
R
S
S
V
W
S
A
F
K
D
Site 156
S2187
L
C
R
S
S
V
W
S
A
F
K
D
Q
K
H
Site 157
S2201
H
D
L
F
I
S
E
S
Q
T
A
G
Y
L
T
Site 158
Y2206
S
E
S
Q
T
A
G
Y
L
T
G
P
G
V
A
Site 159
T2208
S
Q
T
A
G
Y
L
T
G
P
G
V
A
G
Y
Site 160
S2226
G
T
S
T
S
V
M
S
N
L
P
P
P
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation