KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SAPS2
Full Name:
Serine/threonine-protein phosphatase 6 regulatory subunit 2
Alias:
dJ579N16.1; KIAA0685; SAP190; SAPS domain family member 2; SAPS domain family, member 2
Type:
Unknown function
Mass (Da):
104940
Number AA:
UniProt ID:
O75170
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
K
F
D
L
N
T
T
S
H
V
D
K
L
L
D
Site 2
S59
Q
C
M
E
E
L
V
S
L
I
T
Q
D
P
P
Site 3
T62
E
E
L
V
S
L
I
T
Q
D
P
P
L
D
M
Site 4
Y77
E
E
K
V
R
F
K
Y
P
N
T
A
C
E
L
Site 5
S93
T
C
D
V
P
Q
I
S
D
R
L
G
G
D
E
Site 6
S101
D
R
L
G
G
D
E
S
L
L
S
L
L
Y
D
Site 7
Y107
E
S
L
L
S
L
L
Y
D
F
L
D
H
E
P
Site 8
T141
R
K
T
E
Q
V
I
T
F
L
K
K
K
D
K
Site 9
S151
K
K
K
D
K
F
I
S
L
V
L
K
H
I
G
Site 10
S202
L
V
E
L
I
H
P
S
Q
D
E
D
R
Q
S
Site 11
S209
S
Q
D
E
D
R
Q
S
N
A
S
Q
T
L
C
Site 12
S212
E
D
R
Q
S
N
A
S
Q
T
L
C
D
I
V
Site 13
T214
R
Q
S
N
A
S
Q
T
L
C
D
I
V
R
L
Site 14
S227
R
L
G
R
D
Q
G
S
Q
L
Q
E
A
L
E
Site 15
T240
L
E
P
D
P
L
L
T
A
L
E
S
Q
D
C
Site 16
T261
N
M
F
D
G
D
R
T
E
S
C
L
V
S
G
Site 17
S263
F
D
G
D
R
T
E
S
C
L
V
S
G
T
Q
Site 18
T269
E
S
C
L
V
S
G
T
Q
V
L
L
T
L
L
Site 19
T274
S
G
T
Q
V
L
L
T
L
L
E
T
R
R
V
Site 20
T278
V
L
L
T
L
L
E
T
R
R
V
G
T
E
G
Site 21
T283
L
E
T
R
R
V
G
T
E
G
L
V
D
S
F
Site 22
S289
G
T
E
G
L
V
D
S
F
S
Q
G
L
E
R
Site 23
S291
E
G
L
V
D
S
F
S
Q
G
L
E
R
S
Y
Site 24
S297
F
S
Q
G
L
E
R
S
Y
A
V
S
S
S
V
Site 25
Y298
S
Q
G
L
E
R
S
Y
A
V
S
S
S
V
L
Site 26
S303
R
S
Y
A
V
S
S
S
V
L
H
G
I
E
P
Site 27
T358
A
A
L
L
H
T
N
T
P
S
I
N
Q
E
L
Site 28
S411
R
E
E
R
T
E
A
S
G
S
E
S
R
V
E
Site 29
S413
E
R
T
E
A
S
G
S
E
S
R
V
E
P
P
Site 30
S415
T
E
A
S
G
S
E
S
R
V
E
P
P
H
E
Site 31
T430
N
G
N
R
S
L
E
T
P
Q
P
A
A
S
L
Site 32
S436
E
T
P
Q
P
A
A
S
L
P
D
N
T
M
V
Site 33
T466
A
W
E
A
N
D
H
T
Q
A
A
G
G
M
R
Site 34
T498
L
E
R
G
P
V
Q
T
H
I
S
E
V
I
R
Site 35
S501
G
P
V
Q
T
H
I
S
E
V
I
R
G
L
P
Site 36
S517
D
C
R
G
R
W
E
S
F
V
E
E
T
L
T
Site 37
T524
S
F
V
E
E
T
L
T
E
T
N
R
R
N
T
Site 38
T526
V
E
E
T
L
T
E
T
N
R
R
N
T
V
D
Site 39
T531
T
E
T
N
R
R
N
T
V
D
L
V
S
T
H
Site 40
S536
R
N
T
V
D
L
V
S
T
H
H
L
H
S
S
Site 41
S543
S
T
H
H
L
H
S
S
S
E
D
E
D
I
E
Site 42
S544
T
H
H
L
H
S
S
S
E
D
E
D
I
E
G
Site 43
S558
G
A
F
P
N
E
L
S
L
Q
Q
A
F
S
D
Site 44
S564
L
S
L
Q
Q
A
F
S
D
Y
Q
I
Q
Q
M
Site 45
Y566
L
Q
Q
A
F
S
D
Y
Q
I
Q
Q
M
T
A
Site 46
S613
N
I
D
A
D
E
D
S
P
S
A
A
L
F
E
Site 47
S615
D
A
D
E
D
S
P
S
A
A
L
F
E
A
C
Site 48
S642
D
E
D
I
W
E
D
S
D
T
R
C
A
A
R
Site 49
S662
R
F
G
A
P
H
A
S
E
S
C
S
K
N
G
Site 50
S664
G
A
P
H
A
S
E
S
C
S
K
N
G
P
E
Site 51
S666
P
H
A
S
E
S
C
S
K
N
G
P
E
R
G
Site 52
S680
G
G
Q
D
G
K
A
S
L
E
A
H
R
D
A
Site 53
S723
V
F
D
E
P
A
N
S
T
P
T
A
P
G
V
Site 54
T724
F
D
E
P
A
N
S
T
P
T
A
P
G
V
V
Site 55
S765
Q
P
F
C
C
S
E
S
G
P
R
C
S
S
P
Site 56
S770
S
E
S
G
P
R
C
S
S
P
V
D
T
E
C
Site 57
S771
E
S
G
P
R
C
S
S
P
V
D
T
E
C
S
Site 58
T775
R
C
S
S
P
V
D
T
E
C
S
H
A
E
G
Site 59
S778
S
P
V
D
T
E
C
S
H
A
E
G
S
R
S
Site 60
S783
E
C
S
H
A
E
G
S
R
S
Q
G
P
E
K
Site 61
S785
S
H
A
E
G
S
R
S
Q
G
P
E
K
A
S
Site 62
S792
S
Q
G
P
E
K
A
S
Q
A
S
Y
F
A
V
Site 63
Y796
E
K
A
S
Q
A
S
Y
F
A
V
S
P
A
S
Site 64
S820
R
K
A
P
L
L
A
S
D
S
S
S
S
G
G
Site 65
S822
A
P
L
L
A
S
D
S
S
S
S
G
G
S
H
Site 66
S823
P
L
L
A
S
D
S
S
S
S
G
G
S
H
S
Site 67
S824
L
L
A
S
D
S
S
S
S
G
G
S
H
S
E
Site 68
S825
L
A
S
D
S
S
S
S
G
G
S
H
S
E
D
Site 69
S828
D
S
S
S
S
G
G
S
H
S
E
D
G
D
Q
Site 70
S830
S
S
S
G
G
S
H
S
E
D
G
D
Q
K
A
Site 71
S839
D
G
D
Q
K
A
A
S
A
M
D
A
V
S
R
Site 72
S845
A
S
A
M
D
A
V
S
R
G
P
G
R
E
A
Site 73
S877
C
A
D
S
R
L
L
S
P
A
C
P
A
P
K
Site 74
T953
T
V
T
K
D
G
K
T
D
A
P
P
E
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation