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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SS18L1
Full Name:
Calcium-responsive transactivator
Alias:
CREST; KIAA0693; S18L1; SS18-like 1; Synovial sarcoma translocation gene on chromosome 18-like 1; SYT 1
Type:
Transcription, coactivator/corepressor
Mass (Da):
42990
Number AA:
396
UniProt ID:
O75177
International Prot ID:
IPI00307278
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
V
A
F
A
S
A
R
P
R
G
K
G
Site 2
Y38
L
I
Q
C
I
L
E
Y
Q
S
K
G
K
T
A
Site 3
T44
E
Y
Q
S
K
G
K
T
A
E
C
T
Q
Y
Q
Site 4
Y50
K
T
A
E
C
T
Q
Y
Q
Q
I
L
H
R
N
Site 5
T63
R
N
L
V
Y
L
A
T
I
A
D
S
N
Q
N
Site 6
S67
Y
L
A
T
I
A
D
S
N
Q
N
M
Q
S
L
Site 7
S73
D
S
N
Q
N
M
Q
S
L
L
P
A
P
P
T
Site 8
T80
S
L
L
P
A
P
P
T
Q
N
M
N
L
G
P
Site 9
T91
N
L
G
P
G
A
L
T
Q
S
G
S
S
Q
G
Site 10
S93
G
P
G
A
L
T
Q
S
G
S
S
Q
G
L
H
Site 11
S95
G
A
L
T
Q
S
G
S
S
Q
G
L
H
S
Q
Site 12
S101
G
S
S
Q
G
L
H
S
Q
G
S
L
S
D
A
Site 13
S104
Q
G
L
H
S
Q
G
S
L
S
D
A
I
S
T
Site 14
S106
L
H
S
Q
G
S
L
S
D
A
I
S
T
G
L
Site 15
S110
G
S
L
S
D
A
I
S
T
G
L
P
P
S
S
Site 16
S117
S
T
G
L
P
P
S
S
L
L
Q
G
Q
I
G
Site 17
S128
G
Q
I
G
N
G
P
S
H
V
S
M
Q
Q
T
Site 18
T135
S
H
V
S
M
Q
Q
T
A
P
N
T
L
P
T
Site 19
T139
M
Q
Q
T
A
P
N
T
L
P
T
T
S
M
S
Site 20
T142
T
A
P
N
T
L
P
T
T
S
M
S
I
S
G
Site 21
T143
A
P
N
T
L
P
T
T
S
M
S
I
S
G
P
Site 22
S144
P
N
T
L
P
T
T
S
M
S
I
S
G
P
G
Site 23
S146
T
L
P
T
T
S
M
S
I
S
G
P
G
Y
S
Site 24
S148
P
T
T
S
M
S
I
S
G
P
G
Y
S
H
A
Site 25
Y152
M
S
I
S
G
P
G
Y
S
H
A
G
P
A
S
Site 26
S153
S
I
S
G
P
G
Y
S
H
A
G
P
A
S
Q
Site 27
S159
Y
S
H
A
G
P
A
S
Q
G
V
P
M
Q
G
Site 28
Y173
G
Q
G
T
I
G
N
Y
V
S
R
T
N
I
N
Site 29
S196
M
Q
Q
Q
A
A
T
S
H
Y
S
S
A
Q
G
Site 30
S200
A
A
T
S
H
Y
S
S
A
Q
G
G
S
Q
H
Site 31
Y208
A
Q
G
G
S
Q
H
Y
Q
G
Q
S
S
I
A
Site 32
S221
I
A
M
M
G
Q
G
S
Q
G
S
S
M
M
G
Site 33
S225
G
Q
G
S
Q
G
S
S
M
M
G
Q
R
P
M
Site 34
Y235
G
Q
R
P
M
A
P
Y
R
P
S
Q
Q
G
S
Site 35
S238
P
M
A
P
Y
R
P
S
Q
Q
G
S
S
Q
Q
Site 36
S242
Y
R
P
S
Q
Q
G
S
S
Q
Q
Y
L
G
Q
Site 37
S243
R
P
S
Q
Q
G
S
S
Q
Q
Y
L
G
Q
E
Site 38
Y246
Q
Q
G
S
S
Q
Q
Y
L
G
Q
E
E
Y
Y
Site 39
Y252
Q
Y
L
G
Q
E
E
Y
Y
G
E
Q
Y
S
H
Site 40
Y253
Y
L
G
Q
E
E
Y
Y
G
E
Q
Y
S
H
S
Site 41
S258
E
Y
Y
G
E
Q
Y
S
H
S
Q
G
A
A
E
Site 42
S260
Y
G
E
Q
Y
S
H
S
Q
G
A
A
E
P
M
Site 43
Y271
A
E
P
M
G
Q
Q
Y
Y
P
D
G
H
G
D
Site 44
Y272
E
P
M
G
Q
Q
Y
Y
P
D
G
H
G
D
Y
Site 45
Y279
Y
P
D
G
H
G
D
Y
A
Y
Q
Q
S
S
Y
Site 46
Y281
D
G
H
G
D
Y
A
Y
Q
Q
S
S
Y
T
E
Site 47
S285
D
Y
A
Y
Q
Q
S
S
Y
T
E
Q
S
Y
D
Site 48
Y286
Y
A
Y
Q
Q
S
S
Y
T
E
Q
S
Y
D
R
Site 49
S290
Q
S
S
Y
T
E
Q
S
Y
D
R
S
F
E
E
Site 50
Y291
S
S
Y
T
E
Q
S
Y
D
R
S
F
E
E
S
Site 51
S294
T
E
Q
S
Y
D
R
S
F
E
E
S
T
Q
H
Site 52
Y302
F
E
E
S
T
Q
H
Y
Y
E
G
G
N
S
Q
Site 53
Y303
E
E
S
T
Q
H
Y
Y
E
G
G
N
S
Q
Y
Site 54
S311
E
G
G
N
S
Q
Y
S
Q
Q
Q
A
G
Y
Q
Site 55
S328
A
A
Q
Q
Q
T
Y
S
Q
Q
Q
Y
P
S
Q
Site 56
Y332
Q
T
Y
S
Q
Q
Q
Y
P
S
Q
Q
S
Y
P
Site 57
S334
Y
S
Q
Q
Q
Y
P
S
Q
Q
S
Y
P
G
Q
Site 58
S337
Q
Q
Y
P
S
Q
Q
S
Y
P
G
Q
Q
Q
G
Site 59
Y338
Q
Y
P
S
Q
Q
S
Y
P
G
Q
Q
Q
G
Y
Site 60
Y345
Y
P
G
Q
Q
Q
G
Y
G
S
A
Q
G
A
P
Site 61
S347
G
Q
Q
Q
G
Y
G
S
A
Q
G
A
P
S
Q
Site 62
S353
G
S
A
Q
G
A
P
S
Q
Y
P
G
Y
Q
Q
Site 63
Y355
A
Q
G
A
P
S
Q
Y
P
G
Y
Q
Q
G
Q
Site 64
Y358
A
P
S
Q
Y
P
G
Y
Q
Q
G
Q
G
Q
Q
Site 65
S368
G
Q
G
Q
Q
Y
G
S
Y
R
A
P
Q
T
A
Site 66
Y369
Q
G
Q
Q
Y
G
S
Y
R
A
P
Q
T
A
P
Site 67
T374
G
S
Y
R
A
P
Q
T
A
P
S
A
Q
Q
Q
Site 68
Y384
S
A
Q
Q
Q
R
P
Y
G
Y
E
Q
G
Q
Y
Site 69
Y391
Y
G
Y
E
Q
G
Q
Y
G
N
Y
Q
Q
_
_
Site 70
Y394
E
Q
G
Q
Y
G
N
Y
Q
Q
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation