PhosphoNET

           
Protein Info 
   
Short Name:  RTN2
Full Name:  Reticulon-2
Alias:  Neuroendocrine-specific protein-like 1; NSPL1; NSP-like protein 1
Type: 
Mass (Da):  59264
Number AA:  545
UniProt ID:  O75298
International Prot ID:  IPI00024983
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030176     Uniprot OncoNet
Molecular Function:  GO:0004871     PhosphoSite+ KinaseNET
Biological Process:  GO:0007165     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16AHCKEAPSTASSTPD
Site 2T17HCKEAPSTASSTPDS
Site 3S19KEAPSTASSTPDSTE
Site 4S20EAPSTASSTPDSTEG
Site 5T21APSTASSTPDSTEGG
Site 6S24TASSTPDSTEGGNDD
Site 7S32TEGGNDDSDFRELHT
Site 8T39SDFRELHTAREFSEE
Site 9S44LHTAREFSEEDEEET
Site 10T52EEDEEETTSQDWGTP
Site 11S53EDEEETTSQDWGTPR
Site 12T58TTSQDWGTPRELTFS
Site 13T63WGTPRELTFSYIAFD
Site 14S75AFDGVVGSGGRRDST
Site 15S81GSGGRRDSTARRPRP
Site 16T82SGGRRDSTARRPRPQ
Site 17S92RPRPQGRSVSEPRDQ
Site 18S94RPQGRSVSEPRDQHP
Site 19S104RDQHPQPSLGDSLES
Site 20S108PQPSLGDSLESIPSL
Site 21S111SLGDSLESIPSLSQS
Site 22S114DSLESIPSLSQSPEP
Site 23S116LESIPSLSQSPEPGR
Site 24S118SIPSLSQSPEPGRRG
Site 25T129GRRGDPDTAPPSERP
Site 26S133DPDTAPPSERPLEDL
Site 27T154LGWVARGTGSGEDSS
Site 28S156WVARGTGSGEDSSTS
Site 29S160GTGSGEDSSTSSSTP
Site 30S161TGSGEDSSTSSSTPL
Site 31T162GSGEDSSTSSSTPLE
Site 32S163SGEDSSTSSSTPLED
Site 33S164GEDSSTSSSTPLEDE
Site 34S165EDSSTSSSTPLEDEE
Site 35T166DSSTSSSTPLEDEEP
Site 36T181QEPNRLETGEAGEEL
Site 37S198RLRLAQPSSPEVLTP
Site 38S199LRLAQPSSPEVLTPQ
Site 39T204PSSPEVLTPQLSPGS
Site 40S208EVLTPQLSPGSGTPQ
Site 41S211TPQLSPGSGTPQAGT
Site 42T213QLSPGSGTPQAGTPS
Site 43T218SGTPQAGTPSPSRSR
Site 44S220TPQAGTPSPSRSRDS
Site 45S222QAGTPSPSRSRDSNS
Site 46S224GTPSPSRSRDSNSGP
Site 47S227SPSRSRDSNSGPEEP
Site 48S229SRSRDSNSGPEEPLL
Site 49S258VRGQCLDSTDQLEFT
Site 50T259RGQCLDSTDQLEFTV
Site 51T265STDQLEFTVEPRLLG
Site 52T311GWVQRGPTPPTPVLR
Site 53T314QRGPTPPTPVLRVLL
Site 54S326VLLKWAKSPRSSGVP
Site 55S329KWAKSPRSSGVPSLS
Site 56S330WAKSPRSSGVPSLSL
Site 57S334PRSSGVPSLSLGADM
Site 58Y350SKVADLLYWKDTRTS
Site 59T356LYWKDTRTSGVVFTG
Site 60S357YWKDTRTSGVVFTGL
Site 61T422AYLDVDLTLTREQTE
Site 62T428LTLTREQTERLSHQI
Site 63S432REQTERLSHQITSRV
Site 64T436ERLSHQITSRVVSAA
Site 65S437RLSHQITSRVVSAAT
Site 66S441QITSRVVSAATQLRH
Site 67Y505HQAQIDQYVGLVTNQ
Site 68T527IRAKIPGTGALASAA
Site 69S532PGTGALASAAAAVSG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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