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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NDUFS2
Full Name:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
Alias:
CI-49kD; Complex I-49kD; EC 1.6.5.3; EC 1.6.99.3; NADH-coenzyme Q reductase; NDUS2
Type:
Mitochondrial membrane respiratory chain NADH dehydrogenase
Mass (Da):
52546
Number AA:
463
UniProt ID:
O75306
International Prot ID:
IPI00025239
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005747
Uniprot
OncoNet
Molecular Function:
GO:0051539
GO:0051287
GO:0008137
PhosphoSite+
KinaseNET
Biological Process:
GO:0006120
GO:0006979
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
V
R
L
P
I
Q
P
S
R
G
V
R
Q
W
Q
Site 2
Y53
Q
F
G
G
A
V
M
Y
P
S
K
E
T
A
H
Site 3
T75
D
V
D
P
P
K
D
T
I
V
K
N
I
T
L
Site 4
T81
D
T
I
V
K
N
I
T
L
N
F
G
P
Q
H
Site 5
T120
I
G
L
L
H
R
G
T
E
K
L
I
E
Y
K
Site 6
T128
E
K
L
I
E
Y
K
T
Y
L
Q
A
L
P
Y
Site 7
Y129
K
L
I
E
Y
K
T
Y
L
Q
A
L
P
Y
F
Site 8
Y135
T
Y
L
Q
A
L
P
Y
F
D
R
L
D
Y
V
Site 9
Y141
P
Y
F
D
R
L
D
Y
V
S
M
M
C
N
E
Site 10
S143
F
D
R
L
D
Y
V
S
M
M
C
N
E
Q
A
Site 11
Y214
R
E
K
M
F
E
F
Y
E
R
V
S
G
A
R
Site 12
S218
F
E
F
Y
E
R
V
S
G
A
R
M
H
A
A
Site 13
Y226
G
A
R
M
H
A
A
Y
I
R
P
G
G
V
H
Site 14
Y245
L
G
L
M
D
D
I
Y
Q
F
S
K
N
F
S
Site 15
S252
Y
Q
F
S
K
N
F
S
L
R
L
D
E
L
E
Site 16
T263
D
E
L
E
E
L
L
T
N
N
R
I
W
R
N
Site 17
T272
N
R
I
W
R
N
R
T
I
D
I
G
V
V
T
Site 18
S296
S
G
V
M
L
R
G
S
G
I
Q
W
D
L
R
Site 19
Y308
D
L
R
K
T
Q
P
Y
D
V
Y
D
Q
V
E
Site 20
Y311
K
T
Q
P
Y
D
V
Y
D
Q
V
E
F
D
V
Site 21
Y327
V
G
S
R
G
D
C
Y
D
R
Y
L
C
R
V
Site 22
Y330
R
G
D
C
Y
D
R
Y
L
C
R
V
E
E
M
Site 23
S340
R
V
E
E
M
R
Q
S
L
R
I
I
A
Q
C
Site 24
S364
K
V
D
D
A
K
V
S
P
P
K
R
A
E
M
Site 25
T373
P
K
R
A
E
M
K
T
S
M
E
S
L
I
H
Site 26
S374
K
R
A
E
M
K
T
S
M
E
S
L
I
H
H
Site 27
S377
E
M
K
T
S
M
E
S
L
I
H
H
F
K
L
Site 28
Y385
L
I
H
H
F
K
L
Y
T
E
G
Y
Q
V
P
Site 29
Y389
F
K
L
Y
T
E
G
Y
Q
V
P
P
G
A
T
Site 30
Y410
P
K
G
E
F
G
V
Y
L
V
S
D
G
S
S
Site 31
S413
E
F
G
V
Y
L
V
S
D
G
S
S
R
P
Y
Site 32
S416
V
Y
L
V
S
D
G
S
S
R
P
Y
R
C
K
Site 33
S417
Y
L
V
S
D
G
S
S
R
P
Y
R
C
K
I
Site 34
Y420
S
D
G
S
S
R
P
Y
R
C
K
I
K
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation