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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DUSP11
Full Name:
RNA/RNP complex-1-interacting phosphatase
Alias:
DUS11; EC 3.1.3.; PIR1; RNA,RNP complex-1 interacting phosphatase
Type:
Protein phosphatase, dual specificity
Mass (Da):
38939
Number AA:
330
UniProt ID:
O75319
International Prot ID:
IPI00020683
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0004725
GO:0008138
PhosphoSite+
KinaseNET
Biological Process:
GO:0006396
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Dual specificity protein phosphatase 11 pan-specific antibody AB-NP048-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NP048-1#Dual specificity protein phosphatase 11 pan-specific antibody AB-NP048-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NP048-2#Dual specificity protein phosphatase 11 pan-specific antibody AB-NP048-3#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NP048-3#Dual specificity protein phosphatase 11 (M1-R14, human) peptide - Powder PE-01BAI99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BAI99#Dual specificity protein phosphatase 11 (V264-H278, human) peptide - Powder PE-01BAJ95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BAJ95#Dual specificity protein phosphatase 11 (S290-R304, human) peptide - Powder PE-01BAK95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BAK95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
W
G
R
R
R
D
F
S
G
R
S
S
A
K
K
Site 2
S21
R
R
D
F
S
G
R
S
S
A
K
K
K
G
G
Site 3
S22
R
D
F
S
G
R
S
S
A
K
K
K
G
G
N
Site 4
Y38
I
P
E
R
W
K
D
Y
L
P
V
G
Q
R
M
Site 5
S60
F
K
V
P
L
Q
K
S
F
E
K
K
L
A
P
Site 6
S72
L
A
P
E
E
C
F
S
P
L
D
L
F
N
K
Site 7
T94
L
G
L
I
I
D
L
T
Y
T
Q
R
Y
Y
K
Site 8
Y95
G
L
I
I
D
L
T
Y
T
Q
R
Y
Y
K
P
Site 9
T96
L
I
I
D
L
T
Y
T
Q
R
Y
Y
K
P
E
Site 10
Y99
D
L
T
Y
T
Q
R
Y
Y
K
P
E
D
L
P
Site 11
Y100
L
T
Y
T
Q
R
Y
Y
K
P
E
D
L
P
E
Site 12
T108
K
P
E
D
L
P
E
T
V
P
Y
L
K
I
F
Site 13
T126
H
Q
V
P
D
D
E
T
I
F
K
F
K
H
A
Site 14
Y195
H
C
L
E
R
Q
N
Y
I
E
D
L
Q
N
G
Site 15
S210
P
I
R
K
N
W
N
S
S
V
P
R
S
S
D
Site 16
S211
I
R
K
N
W
N
S
S
V
P
R
S
S
D
F
Site 17
S215
W
N
S
S
V
P
R
S
S
D
F
E
D
S
A
Site 18
S216
N
S
S
V
P
R
S
S
D
F
E
D
S
A
H
Site 19
S221
R
S
S
D
F
E
D
S
A
H
L
M
Q
P
V
Site 20
Y239
P
V
K
Q
G
P
R
Y
N
L
H
Q
I
Q
G
Site 21
T255
S
A
P
R
H
F
H
T
Q
T
Q
S
L
Q
Q
Site 22
T257
P
R
H
F
H
T
Q
T
Q
S
L
Q
Q
S
V
Site 23
S259
H
F
H
T
Q
T
Q
S
L
Q
Q
S
V
R
K
Site 24
S263
Q
T
Q
S
L
Q
Q
S
V
R
K
F
S
E
N
Site 25
S268
Q
Q
S
V
R
K
F
S
E
N
P
H
V
Y
Q
Site 26
Y274
F
S
E
N
P
H
V
Y
Q
R
H
H
L
P
P
Site 27
Y289
P
G
P
P
G
E
D
Y
S
H
R
R
Y
S
W
Site 28
Y294
E
D
Y
S
H
R
R
Y
S
W
N
V
K
P
N
Site 29
S295
D
Y
S
H
R
R
Y
S
W
N
V
K
P
N
A
Site 30
Y313
A
Q
D
R
R
R
W
Y
P
Y
N
Y
S
R
L
Site 31
Y315
D
R
R
R
W
Y
P
Y
N
Y
S
R
L
S
Y
Site 32
Y317
R
R
W
Y
P
Y
N
Y
S
R
L
S
Y
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation