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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ENTPD5
Full Name:
Ectonucleoside triphosphate diphosphohydrolase 5
Alias:
CD39 antigen-like 4; CD39L4; EC 3.6.1.6; ENTP5; ER-UDPase; MGC163357; MGC163359; NTPDase 5; NTPDase-5; Nucleoside diphosphatase; PCPH
Type:
Uncharacterized protein
Mass (Da):
47517
Number AA:
428
UniProt ID:
O75356
International Prot ID:
IPI00215952
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005788
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0000287
GO:0017110
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y65
T
G
T
R
I
H
V
Y
T
F
V
Q
K
M
P
Site 2
T66
G
T
R
I
H
V
Y
T
F
V
Q
K
M
P
G
Site 3
S91
D
S
V
K
P
G
L
S
A
F
V
D
Q
P
K
Site 4
T103
Q
P
K
Q
G
A
E
T
V
Q
G
L
L
E
V
Site 5
S114
L
L
E
V
A
K
D
S
I
P
R
S
H
W
K
Site 6
S118
A
K
D
S
I
P
R
S
H
W
K
K
T
P
V
Site 7
T123
P
R
S
H
W
K
K
T
P
V
V
L
K
A
T
Site 8
S155
V
K
E
I
F
R
K
S
P
F
L
V
P
K
G
Site 9
S165
L
V
P
K
G
S
V
S
I
M
D
G
S
D
E
Site 10
T194
L
H
G
H
R
Q
E
T
V
G
T
L
D
L
G
Site 11
T197
H
R
Q
E
T
V
G
T
L
D
L
G
G
A
S
Site 12
T208
G
G
A
S
T
Q
I
T
F
L
P
Q
F
E
K
Site 13
T216
F
L
P
Q
F
E
K
T
L
E
Q
T
P
R
G
Site 14
T220
F
E
K
T
L
E
Q
T
P
R
G
Y
L
T
S
Site 15
Y224
L
E
Q
T
P
R
G
Y
L
T
S
F
E
M
F
Site 16
S227
T
P
R
G
Y
L
T
S
F
E
M
F
N
S
T
Site 17
T234
S
F
E
M
F
N
S
T
Y
K
L
Y
T
H
S
Site 18
Y235
F
E
M
F
N
S
T
Y
K
L
Y
T
H
S
Y
Site 19
Y238
F
N
S
T
Y
K
L
Y
T
H
S
Y
L
G
F
Site 20
T239
N
S
T
Y
K
L
Y
T
H
S
Y
L
G
F
G
Site 21
S241
T
Y
K
L
Y
T
H
S
Y
L
G
F
G
L
K
Site 22
Y242
Y
K
L
Y
T
H
S
Y
L
G
F
G
L
K
A
Site 23
T263
G
A
L
E
T
E
G
T
D
G
H
T
F
R
S
Site 24
T267
T
E
G
T
D
G
H
T
F
R
S
A
C
L
P
Site 25
Y288
W
I
F
G
G
V
K
Y
Q
Y
G
G
N
Q
E
Site 26
Y290
F
G
G
V
K
Y
Q
Y
G
G
N
Q
E
G
E
Site 27
S325
P
E
E
V
Q
R
G
S
F
Y
A
F
S
Y
Y
Site 28
Y327
E
V
Q
R
G
S
F
Y
A
F
S
Y
Y
Y
D
Site 29
Y332
S
F
Y
A
F
S
Y
Y
Y
D
R
A
V
D
T
Site 30
Y333
F
Y
A
F
S
Y
Y
Y
D
R
A
V
D
T
D
Site 31
Y344
V
D
T
D
M
I
D
Y
E
K
G
G
I
L
K
Site 32
S371
D
N
L
E
N
F
T
S
G
S
P
F
L
C
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation