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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PROP1
Full Name:
Homeobox protein prophet of Pit-1
Alias:
Pituitary-specific homeodomain factor
Type:
Mass (Da):
24957
Number AA:
226
UniProt ID:
O75360
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
P
K
K
G
R
V
G
S
S
L
L
P
E
R
H
Site 2
S20
K
K
G
R
V
G
S
S
L
L
P
E
R
H
P
Site 3
T29
L
P
E
R
H
P
A
T
G
T
P
T
T
T
V
Site 4
T31
E
R
H
P
A
T
G
T
P
T
T
T
V
D
S
Site 5
T34
P
A
T
G
T
P
T
T
T
V
D
S
S
A
P
Site 6
T35
A
T
G
T
P
T
T
T
V
D
S
S
A
P
P
Site 7
S39
P
T
T
T
V
D
S
S
A
P
P
C
R
R
L
Site 8
S54
P
G
A
G
G
G
R
S
R
F
S
P
Q
G
G
Site 9
S57
G
G
G
R
S
R
F
S
P
Q
G
G
Q
R
G
Site 10
S68
G
Q
R
G
R
P
H
S
R
R
R
H
R
T
T
Site 11
T74
H
S
R
R
R
H
R
T
T
F
S
P
V
Q
L
Site 12
T75
S
R
R
R
H
R
T
T
F
S
P
V
Q
L
E
Site 13
S77
R
R
H
R
T
T
F
S
P
V
Q
L
E
Q
L
Site 14
S86
V
Q
L
E
Q
L
E
S
A
F
G
R
N
Q
Y
Site 15
Y93
S
A
F
G
R
N
Q
Y
P
D
I
W
A
R
E
Site 16
S101
P
D
I
W
A
R
E
S
L
A
R
D
T
G
L
Site 17
T106
R
E
S
L
A
R
D
T
G
L
S
E
A
R
I
Site 18
S109
L
A
R
D
T
G
L
S
E
A
R
I
Q
V
W
Site 19
S130
K
Q
R
K
Q
E
R
S
L
L
Q
P
L
A
H
Site 20
S150
F
S
S
F
L
P
E
S
T
A
C
P
Y
S
Y
Site 21
T151
S
S
F
L
P
E
S
T
A
C
P
Y
S
Y
A
Site 22
S156
E
S
T
A
C
P
Y
S
Y
A
A
P
P
P
P
Site 23
Y157
S
T
A
C
P
Y
S
Y
A
A
P
P
P
P
V
Site 24
T165
A
A
P
P
P
P
V
T
C
F
P
H
P
Y
S
Site 25
Y171
V
T
C
F
P
H
P
Y
S
H
A
L
P
S
Q
Site 26
S172
T
C
F
P
H
P
Y
S
H
A
L
P
S
Q
P
Site 27
S177
P
Y
S
H
A
L
P
S
Q
P
S
T
G
G
A
Site 28
S188
T
G
G
A
F
A
L
S
H
Q
S
E
D
W
Y
Site 29
Y195
S
H
Q
S
E
D
W
Y
P
T
L
H
P
A
P
Site 30
T197
Q
S
E
D
W
Y
P
T
L
H
P
A
P
A
G
Site 31
S218
P
P
P
M
L
P
L
S
L
E
P
S
K
S
W
Site 32
S222
L
P
L
S
L
E
P
S
K
S
W
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation