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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BCAS1
Full Name:
Breast carcinoma-amplified sequence 1
Alias:
AIBC1; Amplified and overexpressed in breast cancer; Breast carcinoma amplified sequence 1; NABC1; Novel amplified in breast cancer 1
Type:
Mass (Da):
61709
Number AA:
584
UniProt ID:
O75363
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
N
E
P
E
A
E
T
Y
Q
D
N
A
S
A
L
Site 2
S62
K
T
D
N
V
A
T
S
S
P
E
T
T
E
I
Site 3
S63
T
D
N
V
A
T
S
S
P
E
T
T
E
I
S
Site 4
T67
A
T
S
S
P
E
T
T
E
I
S
A
V
A
D
Site 5
S100
S
R
F
F
L
M
L
S
R
P
V
P
G
R
T
Site 6
S114
T
G
D
Q
A
A
D
S
S
L
G
S
V
K
L
Site 7
S115
G
D
Q
A
A
D
S
S
L
G
S
V
K
L
D
Site 8
S118
A
A
D
S
S
L
G
S
V
K
L
D
V
S
S
Site 9
S124
G
S
V
K
L
D
V
S
S
N
K
A
P
A
N
Site 10
S135
A
P
A
N
K
D
P
S
E
S
W
T
L
P
V
Site 11
T139
K
D
P
S
E
S
W
T
L
P
V
A
A
G
P
Site 12
T150
A
A
G
P
G
Q
D
T
D
K
T
P
G
H
A
Site 13
T153
P
G
Q
D
T
D
K
T
P
G
H
A
P
A
Q
Site 14
S165
P
A
Q
D
K
V
L
S
A
A
R
D
P
T
L
Site 15
T171
L
S
A
A
R
D
P
T
L
L
P
P
E
T
G
Site 16
T177
P
T
L
L
P
P
E
T
G
G
A
G
G
E
A
Site 17
S186
G
A
G
G
E
A
P
S
K
P
K
D
S
S
F
Site 18
S191
A
P
S
K
P
K
D
S
S
F
F
D
K
F
F
Site 19
S192
P
S
K
P
K
D
S
S
F
F
D
K
F
F
K
Site 20
S260
E
L
G
T
A
D
C
S
V
P
G
D
P
E
G
Site 21
T270
G
D
P
E
G
L
E
T
A
K
D
D
S
Q
A
Site 22
S275
L
E
T
A
K
D
D
S
Q
A
A
A
I
A
E
Site 23
S289
E
N
N
N
S
I
M
S
F
F
K
T
L
V
S
Site 24
S296
S
F
F
K
T
L
V
S
P
N
K
A
E
T
K
Site 25
S314
E
D
T
G
A
E
K
S
P
T
T
S
A
D
L
Site 26
T316
T
G
A
E
K
S
P
T
T
S
A
D
L
K
S
Site 27
T317
G
A
E
K
S
P
T
T
S
A
D
L
K
S
D
Site 28
S318
A
E
K
S
P
T
T
S
A
D
L
K
S
D
K
Site 29
S323
T
T
S
A
D
L
K
S
D
K
A
N
F
T
S
Site 30
S330
S
D
K
A
N
F
T
S
Q
E
T
Q
G
A
G
Site 31
S346
N
S
K
G
C
N
P
S
G
H
T
Q
S
V
T
Site 32
S351
N
P
S
G
H
T
Q
S
V
T
T
P
E
P
A
Site 33
T354
G
H
T
Q
S
V
T
T
P
E
P
A
K
E
G
Site 34
S366
K
E
G
T
K
E
K
S
G
P
T
S
L
P
L
Site 35
S370
K
E
K
S
G
P
T
S
L
P
L
G
K
L
F
Site 36
S381
G
K
L
F
W
K
K
S
V
K
E
D
S
V
P
Site 37
S386
K
K
S
V
K
E
D
S
V
P
T
G
A
E
E
Site 38
S399
E
E
N
V
V
C
E
S
P
V
E
I
I
K
S
Site 39
S406
S
P
V
E
I
I
K
S
K
E
V
E
S
A
L
Site 40
T415
E
V
E
S
A
L
Q
T
V
D
L
N
E
G
D
Site 41
S437
A
K
L
K
R
E
E
S
K
P
R
T
S
L
M
Site 42
T441
R
E
E
S
K
P
R
T
S
L
M
A
F
L
R
Site 43
S442
E
E
S
K
P
R
T
S
L
M
A
F
L
R
Q
Site 44
S451
M
A
F
L
R
Q
M
S
V
K
G
D
G
G
I
Site 45
S461
G
D
G
G
I
T
H
S
E
E
I
N
G
K
D
Site 46
S469
E
E
I
N
G
K
D
S
S
C
Q
T
S
D
S
Site 47
S470
E
I
N
G
K
D
S
S
C
Q
T
S
D
S
T
Site 48
T473
G
K
D
S
S
C
Q
T
S
D
S
T
E
K
T
Site 49
S474
K
D
S
S
C
Q
T
S
D
S
T
E
K
T
I
Site 50
S476
S
S
C
Q
T
S
D
S
T
E
K
T
I
T
P
Site 51
T480
T
S
D
S
T
E
K
T
I
T
P
P
E
P
E
Site 52
T482
D
S
T
E
K
T
I
T
P
P
E
P
E
P
T
Site 53
T489
T
P
P
E
P
E
P
T
G
A
P
Q
K
G
K
Site 54
S500
Q
K
G
K
E
G
S
S
K
D
K
K
S
A
A
Site 55
S505
G
S
S
K
D
K
K
S
A
A
E
M
N
K
Q
Site 56
S514
A
E
M
N
K
Q
K
S
N
K
Q
E
A
K
E
Site 57
T530
A
Q
C
T
E
Q
A
T
V
D
T
N
S
L
Q
Site 58
S552
R
P
E
K
R
Q
Q
S
L
G
G
F
F
K
G
Site 59
S576
Q
V
Q
T
D
P
V
S
I
G
P
V
G
K
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation