PhosphoNET

           
Protein Info 
   
Short Name:  ULK1
Full Name:  Serine/threonine-protein kinase ULK1
Alias:  EC 2.7.1.37; EC 2.7.11.1; Unc-51-like kinase 1
Type:  Protein-serine kinase, Other group, ULK family
Mass (Da):  112601
Number AA:  1050
UniProt ID:  O75385
International Prot ID:  IPI00289357
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0070969  GO:0005776  GO:0005829 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0032403  GO:0004674 PhosphoSite+ KinaseNET
Biological Process:  GO:0008104  GO:0010506  GO:0006468 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T8MEPGRGGTETVGKFE
Site 2T10PGRGGTETVGKFEFS
Site 3S56NKKNLAKSQTLLGKE
Site 4T58KNLAKSQTLLGKEIK
Site 5Y79HENIVALYDFQEMAN
Site 6Y89QEMANSVYLVMEYCN
Site 7Y103NGGDLADYLHAMRTL
Site 8T109DYLHAMRTLSEDTIR
Site 9S111LHAMRTLSEDTIRLF
Site 10T114MRTLSEDTIRLFLQQ
Site 11S147KPQNILLSNPAGRRA
Site 12S158GRRANPNSIRVKIAD
Site 13Y171ADFGFARYLQSNMMA
Site 14S225KAPFQASSPQDLRLF
Site 15Y233PQDLRLFYEKNKTLV
Site 16T238LFYEKNKTLVPTIPR
Site 17T247VPTIPRETSAPLRQL
Site 18S248PTIPRETSAPLRQLL
Site 19S281HHPFLDASPSVRKSP
Site 20S283PFLDASPSVRKSPPV
Site 21S287ASPSVRKSPPVPVPS
Site 22S294SPPVPVPSYPSSGSG
Site 23Y295PPVPVPSYPSSGSGS
Site 24S297VPVPSYPSSGSGSSS
Site 25S298PVPSYPSSGSGSSSS
Site 26S300PSYPSSGSGSSSSSS
Site 27S302YPSSGSGSSSSSSST
Site 28S303PSSGSGSSSSSSSTS
Site 29S304SSGSGSSSSSSSTSH
Site 30S305SGSGSSSSSSSTSHL
Site 31S306GSGSSSSSSSTSHLA
Site 32S307SGSSSSSSSTSHLAS
Site 33S308GSSSSSSSTSHLASP
Site 34T309SSSSSSSTSHLASPP
Site 35S310SSSSSSTSHLASPPS
Site 36S314SSTSHLASPPSLGEM
Site 37S317SHLASPPSLGEMQQL
Site 38T327EMQQLQKTLASPADT
Site 39S330QLQKTLASPADTAGF
Site 40S340DTAGFLHSSRDSGGS
Site 41S341TAGFLHSSRDSGGSK
Site 42S344FLHSSRDSGGSKDSS
Site 43S347SSRDSGGSKDSSCDT
Site 44S350DSGGSKDSSCDTDDF
Site 45S351SGGSKDSSCDTDDFV
Site 46T354SKDSSCDTDDFVMVP
Site 47S374DLVAEAPSAKPPPDS
Site 48S381SAKPPPDSLMCSGSS
Site 49S392SGSSLVASAGLESHG
Site 50S397VASAGLESHGRTPSP
Site 51T401GLESHGRTPSPSPPC
Site 52S403ESHGRTPSPSPPCSS
Site 53S405HGRTPSPSPPCSSSP
Site 54S409PSPSPPCSSSPSPSG
Site 55S410SPSPPCSSSPSPSGR
Site 56S411PSPPCSSSPSPSGRA
Site 57S413PPCSSSPSPSGRAGP
Site 58S415CSSSPSPSGRAGPFS
Site 59S422SGRAGPFSSSRCGAS
Site 60S423GRAGPFSSSRCGASV
Site 61S424RAGPFSSSRCGASVP
Site 62S429SSSRCGASVPIPVPT
Site 63Y441VPTQVQNYQRIERNL
Site 64S450RIERNLQSPTQFQTP
Site 65T456QSPTQFQTPRSSAIR
Site 66S459TQFQTPRSSAIRRSG
Site 67S460QFQTPRSSAIRRSGS
Site 68S465RSSAIRRSGSTSPLG
Site 69S467SAIRRSGSTSPLGFA
Site 70T468AIRRSGSTSPLGFAR
Site 71S469IRRSGSTSPLGFARA
Site 72S477PLGFARASPSPPAHA
Site 73S479GFARASPSPPAHAEH
Site 74S495GVLARKMSLGGGRPY
Site 75Y502SLGGGRPYTPSPQVG
Site 76T503LGGGRPYTPSPQVGT
Site 77S505GGRPYTPSPQVGTIP
Site 78S518IPERPGWSGTPSPQG
Site 79T520ERPGWSGTPSPQGAE
Site 80S522PGWSGTPSPQGAEMR
Site 81S533AEMRGGRSPRPGSSA
Site 82S538GRSPRPGSSAPEHSP
Site 83S539RSPRPGSSAPEHSPR
Site 84S544GSSAPEHSPRTSGLG
Site 85S548PEHSPRTSGLGCRLH
Site 86S556GLGCRLHSAPNLSDL
Site 87S561LHSAPNLSDLHVVRP
Site 88T575PKLPKPPTDPLGAVF
Site 89S583DPLGAVFSPPQASPP
Site 90S588VFSPPQASPPQPSHG
Site 91S593QASPPQPSHGLQSCR
Site 92S598QPSHGLQSCRNLRGS
Site 93S605SCRNLRGSPKLPDFL
Site 94S623PLPPILGSPTKAVPS
Site 95T625PPILGSPTKAVPSFD
Site 96S630SPTKAVPSFDFPKTP
Site 97T636PSFDFPKTPSSQNLL
Site 98S638FDFPKTPSSQNLLAL
Site 99S639DFPKTPSSQNLLALL
Site 100T654ARQGVVMTPPRNRTL
Site 101T660MTPPRNRTLPDLSEV
Site 102S665NRTLPDLSEVGPFHG
Site 103S692PKGPFGRSFSTSRLT
Site 104S694GPFGRSFSTSRLTDL
Site 105T699SFSTSRLTDLLLKAA
Site 106T709LLKAAFGTQAPDPGS
Site 107S716TQAPDPGSTESLQEK
Site 108S719PDPGSTESLQEKPME
Site 109S736PSAGFGGSLHPGARA
Site 110T746PGARAGGTSSPSPVV
Site 111S747GARAGGTSSPSPVVF
Site 112S748ARAGGTSSPSPVVFT
Site 113S758PVVFTVGSPPSGSTP
Site 114S761FTVGSPPSGSTPPQG
Site 115S763VGSPPSGSTPPQGPR
Site 116T764GSPPSGSTPPQGPRT
Site 117T771TPPQGPRTRMFSAGP
Site 118S775GPRTRMFSAGPTGSA
Site 119T779RMFSAGPTGSASSSA
Site 120S781FSAGPTGSASSSARH
Site 121S783AGPTGSASSSARHLV
Site 122S784GPTGSASSSARHLVP
Site 123S785PTGSASSSARHLVPG
Site 124S795HLVPGPCSEAPAPEL
Site 125T841TLMEQEHTEILRGLR
Site 126S868AALKGSASEAAGGPE
Site 127Y876EAAGGPEYQLQESVV
Site 128S881PEYQLQESVVADQIS
Site 129T931GKLCLSSTVKQVVRR
Site 130Y943VRRLNELYKASVVSC
Site 131S949LYKASVVSCQGLSLR
Site 132S1022EGLQHMLSDQADIEN
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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