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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TACC1
Full Name:
Transforming acidic coiled-coil-containing protein 1
Alias:
Gastric cancer antigen Ga55; KIAA1103; Taxin 1; Transforming, acidic coiled-coil containing protein 1
Type:
Unknown function
Mass (Da):
87794
Number AA:
805
UniProt ID:
O75410
International Prot ID:
IPI00025683
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0051301
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
F
S
P
W
Q
I
L
S
P
Site 2
S10
F
S
P
W
Q
I
L
S
P
V
Q
W
A
K
W
Site 3
S44
G
D
P
E
E
E
D
S
Q
A
E
T
K
S
L
Site 4
T48
E
E
D
S
Q
A
E
T
K
S
L
S
F
S
S
Site 5
S50
D
S
Q
A
E
T
K
S
L
S
F
S
S
D
S
Site 6
S52
Q
A
E
T
K
S
L
S
F
S
S
D
S
E
G
Site 7
S54
E
T
K
S
L
S
F
S
S
D
S
E
G
N
F
Site 8
S55
T
K
S
L
S
F
S
S
D
S
E
G
N
F
E
Site 9
S57
S
L
S
F
S
S
D
S
E
G
N
F
E
T
P
Site 10
T63
D
S
E
G
N
F
E
T
P
E
A
E
T
P
I
Site 11
T68
F
E
T
P
E
A
E
T
P
I
R
S
P
F
K
Site 12
S72
E
A
E
T
P
I
R
S
P
F
K
E
S
C
D
Site 13
S77
I
R
S
P
F
K
E
S
C
D
P
S
L
G
L
Site 14
S81
F
K
E
S
C
D
P
S
L
G
L
A
G
P
G
Site 15
S91
L
A
G
P
G
A
K
S
Q
E
S
Q
E
A
D
Site 16
S94
P
G
A
K
S
Q
E
S
Q
E
A
D
E
Q
L
Site 17
S111
E
V
V
E
K
C
S
S
K
T
C
S
K
P
S
Site 18
T113
V
E
K
C
S
S
K
T
C
S
K
P
S
E
N
Site 19
S115
K
C
S
S
K
T
C
S
K
P
S
E
N
E
V
Site 20
S118
S
K
T
C
S
K
P
S
E
N
E
V
P
Q
Q
Site 21
S129
V
P
Q
Q
A
I
D
S
H
S
V
K
N
F
R
Site 22
S131
Q
Q
A
I
D
S
H
S
V
K
N
F
R
E
E
Site 23
S144
E
E
P
E
H
D
F
S
K
I
S
I
V
R
P
Site 24
S147
E
H
D
F
S
K
I
S
I
V
R
P
F
S
I
Site 25
S153
I
S
I
V
R
P
F
S
I
E
T
K
D
S
T
Site 26
T160
S
I
E
T
K
D
S
T
D
I
S
A
V
L
G
Site 27
S163
T
K
D
S
T
D
I
S
A
V
L
G
T
K
A
Site 28
T168
D
I
S
A
V
L
G
T
K
A
A
H
G
C
V
Site 29
S179
H
G
C
V
T
A
V
S
G
K
A
L
P
S
S
Site 30
S185
V
S
G
K
A
L
P
S
S
P
P
D
A
L
Q
Site 31
S186
S
G
K
A
L
P
S
S
P
P
D
A
L
Q
D
Site 32
T204
T
E
G
S
M
G
V
T
L
E
A
S
A
E
A
Site 33
S218
A
D
L
K
A
G
N
S
C
P
E
L
V
P
S
Site 34
S225
S
C
P
E
L
V
P
S
R
R
S
K
L
R
K
Site 35
S228
E
L
V
P
S
R
R
S
K
L
R
K
P
K
P
Site 36
T250
I
G
G
E
F
S
D
T
N
A
A
V
E
G
T
Site 37
T257
T
N
A
A
V
E
G
T
P
L
P
K
A
S
Y
Site 38
S263
G
T
P
L
P
K
A
S
Y
H
F
S
P
E
E
Site 39
Y264
T
P
L
P
K
A
S
Y
H
F
S
P
E
E
L
Site 40
S267
P
K
A
S
Y
H
F
S
P
E
E
L
D
E
N
Site 41
T275
P
E
E
L
D
E
N
T
S
P
L
L
G
D
A
Site 42
S276
E
E
L
D
E
N
T
S
P
L
L
G
D
A
R
Site 43
S287
G
D
A
R
F
Q
K
S
P
P
D
L
K
E
T
Site 44
T294
S
P
P
D
L
K
E
T
P
G
T
L
S
S
D
Site 45
T297
D
L
K
E
T
P
G
T
L
S
S
D
T
N
D
Site 46
S300
E
T
P
G
T
L
S
S
D
T
N
D
S
G
V
Site 47
T302
P
G
T
L
S
S
D
T
N
D
S
G
V
E
L
Site 48
S305
L
S
S
D
T
N
D
S
G
V
E
L
G
E
E
Site 49
S313
G
V
E
L
G
E
E
S
R
S
S
P
L
K
L
Site 50
S315
E
L
G
E
E
S
R
S
S
P
L
K
L
E
F
Site 51
S316
L
G
E
E
S
R
S
S
P
L
K
L
E
F
D
Site 52
T325
L
K
L
E
F
D
F
T
E
D
T
G
N
I
E
Site 53
T328
E
F
D
F
T
E
D
T
G
N
I
E
A
R
K
Site 54
S347
K
L
G
R
K
L
G
S
T
L
T
P
K
I
Q
Site 55
T348
L
G
R
K
L
G
S
T
L
T
P
K
I
Q
K
Site 56
T350
R
K
L
G
S
T
L
T
P
K
I
Q
K
D
G
Site 57
S359
K
I
Q
K
D
G
I
S
K
S
A
G
L
E
Q
Site 58
S361
Q
K
D
G
I
S
K
S
A
G
L
E
Q
P
T
Site 59
S378
V
A
R
D
G
P
L
S
Q
T
S
S
K
P
D
Site 60
S381
D
G
P
L
S
Q
T
S
S
K
P
D
P
S
Q
Site 61
S382
G
P
L
S
Q
T
S
S
K
P
D
P
S
Q
W
Site 62
S387
T
S
S
K
P
D
P
S
Q
W
E
S
P
S
F
Site 63
S391
P
D
P
S
Q
W
E
S
P
S
F
N
P
F
G
Site 64
S393
P
S
Q
W
E
S
P
S
F
N
P
F
G
S
H
Site 65
S399
P
S
F
N
P
F
G
S
H
S
V
L
Q
N
S
Site 66
S401
F
N
P
F
G
S
H
S
V
L
Q
N
S
P
P
Site 67
S406
S
H
S
V
L
Q
N
S
P
P
L
S
S
E
G
Site 68
S410
L
Q
N
S
P
P
L
S
S
E
G
S
Y
H
F
Site 69
S411
Q
N
S
P
P
L
S
S
E
G
S
Y
H
F
D
Site 70
S414
P
P
L
S
S
E
G
S
Y
H
F
D
P
D
N
Site 71
Y415
P
L
S
S
E
G
S
Y
H
F
D
P
D
N
F
Site 72
S425
D
P
D
N
F
D
E
S
M
D
P
F
K
P
T
Site 73
T432
S
M
D
P
F
K
P
T
T
T
L
T
S
S
D
Site 74
T433
M
D
P
F
K
P
T
T
T
L
T
S
S
D
F
Site 75
T434
D
P
F
K
P
T
T
T
L
T
S
S
D
F
C
Site 76
T436
F
K
P
T
T
T
L
T
S
S
D
F
C
S
P
Site 77
S437
K
P
T
T
T
L
T
S
S
D
F
C
S
P
T
Site 78
S438
P
T
T
T
L
T
S
S
D
F
C
S
P
T
G
Site 79
S442
L
T
S
S
D
F
C
S
P
T
G
N
H
V
N
Site 80
S454
H
V
N
E
I
L
E
S
P
K
K
A
K
S
R
Site 81
S460
E
S
P
K
K
A
K
S
R
L
I
T
S
G
C
Site 82
T464
K
A
K
S
R
L
I
T
S
G
C
K
V
K
K
Site 83
S476
V
K
K
H
E
T
Q
S
L
A
L
D
A
C
S
Site 84
S483
S
L
A
L
D
A
C
S
R
D
E
G
A
V
I
Site 85
S491
R
D
E
G
A
V
I
S
Q
I
S
D
I
S
N
Site 86
S497
I
S
Q
I
S
D
I
S
N
R
D
G
H
A
T
Site 87
T504
S
N
R
D
G
H
A
T
D
E
E
K
L
A
S
Site 88
S511
T
D
E
E
K
L
A
S
T
S
C
G
Q
K
S
Site 89
S513
E
E
K
L
A
S
T
S
C
G
Q
K
S
A
G
Site 90
S518
S
T
S
C
G
Q
K
S
A
G
A
E
V
K
G
Site 91
Y533
E
P
E
E
D
L
E
Y
F
E
C
S
N
V
P
Site 92
S542
E
C
S
N
V
P
V
S
T
I
N
H
A
F
S
Site 93
S551
I
N
H
A
F
S
S
S
E
A
G
I
E
K
E
Site 94
S568
Q
K
M
E
E
D
G
S
T
V
L
G
L
L
E
Site 95
T569
K
M
E
E
D
G
S
T
V
L
G
L
L
E
S
Site 96
S584
S
A
E
K
A
P
V
S
V
S
C
G
G
E
S
Site 97
S586
E
K
A
P
V
S
V
S
C
G
G
E
S
P
L
Site 98
S591
S
V
S
C
G
G
E
S
P
L
D
G
I
C
L
Site 99
S599
P
L
D
G
I
C
L
S
E
S
D
K
T
A
V
Site 100
T616
L
I
R
E
E
I
I
T
K
E
I
E
A
N
E
Site 101
Y628
A
N
E
W
K
K
K
Y
E
E
T
R
Q
E
V
Site 102
T648
I
V
A
E
Y
E
K
T
I
A
Q
M
I
E
D
Site 103
S660
I
E
D
E
Q
R
T
S
M
T
S
Q
K
S
F
Site 104
S663
E
Q
R
T
S
M
T
S
Q
K
S
F
Q
Q
L
Site 105
S666
T
S
M
T
S
Q
K
S
F
Q
Q
L
T
M
E
Site 106
S683
Q
A
L
A
D
L
N
S
V
E
R
S
L
S
D
Site 107
S687
D
L
N
S
V
E
R
S
L
S
D
L
F
R
R
Site 108
S689
N
S
V
E
R
S
L
S
D
L
F
R
R
Y
E
Site 109
Y695
L
S
D
L
F
R
R
Y
E
N
L
K
G
V
L
Site 110
Y719
L
K
K
C
A
Q
D
Y
L
A
R
V
K
Q
E
Site 111
Y730
V
K
Q
E
E
Q
R
Y
Q
A
L
K
I
H
A
Site 112
S775
K
E
Q
M
K
V
E
S
L
E
R
A
L
Q
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation