KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TECTA
Full Name:
Alpha-tectorin
Alias:
Type:
Mass (Da):
239554
Number AA:
2155
UniProt ID:
O75443
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
A
Q
P
R
E
L
M
Y
P
F
W
Q
N
D
T
Site 2
T38
F
W
Q
N
D
T
K
T
P
K
V
D
D
G
S
Site 3
S45
T
P
K
V
D
D
G
S
S
S
E
I
K
L
A
Site 4
S46
P
K
V
D
D
G
S
S
S
E
I
K
L
A
I
Site 5
S47
K
V
D
D
G
S
S
S
E
I
K
L
A
I
P
Site 6
Y66
G
V
P
Y
R
T
V
Y
V
N
N
N
G
V
V
Site 7
S86
V
S
Q
F
T
P
E
S
F
P
L
T
D
G
R
Site 8
T90
T
P
E
S
F
P
L
T
D
G
R
A
F
V
A
Site 9
Y112
N
G
I
R
G
E
I
Y
Y
R
E
T
M
E
P
Site 10
Y113
G
I
R
G
E
I
Y
Y
R
E
T
M
E
P
A
Site 11
T116
G
E
I
Y
Y
R
E
T
M
E
P
A
I
L
K
Site 12
T126
P
A
I
L
K
R
A
T
K
D
I
R
K
Y
F
Site 13
Y132
A
T
K
D
I
R
K
Y
F
K
D
M
A
T
F
Site 14
T153
I
V
T
W
E
E
V
T
F
Y
G
G
S
S
T
Site 15
Y155
T
W
E
E
V
T
F
Y
G
G
S
S
T
T
P
Site 16
T161
F
Y
G
G
S
S
T
T
P
V
N
T
F
Q
A
Site 17
T179
S
D
G
S
Y
T
F
T
L
F
N
Y
Y
E
I
Site 18
Y184
T
F
T
L
F
N
Y
Y
E
I
N
W
T
T
G
Site 19
S194
N
W
T
T
G
T
A
S
G
G
D
P
L
T
G
Site 20
T217
G
F
N
G
G
N
L
T
N
F
F
S
L
P
G
Site 21
S221
G
N
L
T
N
F
F
S
L
P
G
S
R
T
P
Site 22
S225
N
F
F
S
L
P
G
S
R
T
P
E
I
V
N
Site 23
T227
F
S
L
P
G
S
R
T
P
E
I
V
N
I
Q
Site 24
S262
D
P
A
N
G
C
T
S
R
G
Q
F
L
R
R
Site 25
Y293
L
D
F
N
N
E
I
Y
C
Q
E
A
S
C
S
Site 26
S300
Y
C
Q
E
A
S
C
S
P
Y
E
V
C
E
P
Site 27
Y302
Q
E
A
S
C
S
P
Y
E
V
C
E
P
K
G
Site 28
Y313
E
P
K
G
K
F
F
Y
C
S
A
V
E
T
S
Site 29
S357
R
Q
C
L
Q
T
S
S
L
P
F
F
S
V
E
Site 30
S362
T
S
S
L
P
F
F
S
V
E
A
K
N
E
H
Site 31
S373
K
N
E
H
R
R
G
S
A
V
S
W
V
K
E
Site 32
S376
H
R
R
G
S
A
V
S
W
V
K
E
L
S
V
Site 33
S382
V
S
W
V
K
E
L
S
V
E
V
N
G
Y
K
Site 34
S396
K
I
L
I
P
K
G
S
Y
G
R
V
K
V
N
Site 35
Y397
I
L
I
P
K
G
S
Y
G
R
V
K
V
N
D
Site 36
Y444
V
T
F
D
G
Q
H
Y
A
S
I
S
V
P
G
Site 37
S446
F
D
G
Q
H
Y
A
S
I
S
V
P
G
S
Y
Site 38
S448
G
Q
H
Y
A
S
I
S
V
P
G
S
Y
I
N
Site 39
S482
P
D
G
R
P
A
M
S
V
L
D
L
G
E
S
Site 40
S489
S
V
L
D
L
G
E
S
W
R
V
Y
H
A
D
Site 41
Y518
D
A
A
T
E
A
L
Y
F
G
S
D
Y
C
G
Site 42
S556
S
C
V
Y
D
L
C
S
V
R
D
N
G
T
L
Site 43
T587
I
P
I
G
D
W
R
T
Q
T
G
C
V
S
T
Site 44
T589
I
G
D
W
R
T
Q
T
G
C
V
S
T
V
Q
Site 45
S593
R
T
Q
T
G
C
V
S
T
V
Q
C
P
S
F
Site 46
T594
T
Q
T
G
C
V
S
T
V
Q
C
P
S
F
S
Site 47
Y603
Q
C
P
S
F
S
H
Y
S
V
C
T
S
S
C
Site 48
T613
C
T
S
S
C
P
D
T
C
S
D
L
T
A
S
Site 49
S615
S
S
C
P
D
T
C
S
D
L
T
A
S
R
N
Site 50
T618
P
D
T
C
S
D
L
T
A
S
R
N
C
A
T
Site 51
T625
T
A
S
R
N
C
A
T
P
C
T
E
G
C
E
Site 52
Y658
G
C
D
F
D
G
H
Y
Y
T
M
G
E
F
F
Site 53
Y684
C
E
E
G
G
D
V
Y
C
F
N
K
T
C
G
Site 54
Y702
V
C
A
V
E
D
G
Y
Q
G
C
F
P
K
R
Site 55
T711
G
C
F
P
K
R
E
T
V
C
L
L
S
Q
N
Site 56
S716
R
E
T
V
C
L
L
S
Q
N
Q
V
L
H
T
Site 57
T723
S
Q
N
Q
V
L
H
T
F
D
G
A
S
Y
A
Site 58
S728
L
H
T
F
D
G
A
S
Y
A
F
P
S
E
F
Site 59
Y729
H
T
F
D
G
A
S
Y
A
F
P
S
E
F
S
Site 60
T738
F
P
S
E
F
S
Y
T
L
L
K
T
C
P
E
Site 61
T742
F
S
Y
T
L
L
K
T
C
P
E
R
P
E
Y
Site 62
Y749
T
C
P
E
R
P
E
Y
L
E
I
D
I
N
K
Site 63
S786
K
I
G
G
I
G
A
S
E
V
K
L
N
G
Q
Site 64
Y809
P
S
G
K
L
E
I
Y
R
N
K
N
S
T
T
Site 65
S814
E
I
Y
R
N
K
N
S
T
T
V
E
S
K
G
Site 66
T815
I
Y
R
N
K
N
S
T
T
V
E
S
K
G
V
Site 67
Y852
T
G
G
L
C
G
F
Y
N
A
N
A
S
D
E
Site 68
S900
L
K
A
C
N
N
D
S
E
L
L
K
F
Y
R
Site 69
Y906
D
S
E
L
L
K
F
Y
R
S
R
S
R
C
G
Site 70
S908
E
L
L
K
F
Y
R
S
R
S
R
C
G
I
I
Site 71
S910
L
K
F
Y
R
S
R
S
R
C
G
I
I
N
D
Site 72
S919
C
G
I
I
N
D
P
S
N
S
S
F
L
E
C
Site 73
S921
I
I
N
D
P
S
N
S
S
F
L
E
C
H
G
Site 74
S922
I
N
D
P
S
N
S
S
F
L
E
C
H
G
V
Site 75
S946
C
L
F
R
L
C
Q
S
G
G
N
E
S
E
L
Site 76
S951
C
Q
S
G
G
N
E
S
E
L
C
D
S
V
A
Site 77
S956
N
E
S
E
L
C
D
S
V
A
R
Y
A
S
A
Site 78
Y960
L
C
D
S
V
A
R
Y
A
S
A
C
K
N
A
Site 79
S962
D
S
V
A
R
Y
A
S
A
C
K
N
A
D
V
Site 80
Y1023
G
C
Q
C
D
E
G
Y
A
L
L
G
S
Q
C
Site 81
S1028
E
G
Y
A
L
L
G
S
Q
C
V
T
R
S
E
Site 82
T1032
L
L
G
S
Q
C
V
T
R
S
E
C
G
C
N
Site 83
Y1082
I
P
C
K
D
D
E
Y
C
M
E
E
G
G
L
Site 84
Y1090
C
M
E
E
G
G
L
Y
Y
C
Q
A
R
T
D
Site 85
S1099
C
Q
A
R
T
D
A
S
C
I
V
S
G
Y
G
Site 86
T1110
S
G
Y
G
H
Y
L
T
F
D
G
F
P
F
D
Site 87
T1129
C
P
L
I
L
C
T
T
G
S
R
P
S
S
D
Site 88
S1131
L
I
L
C
T
T
G
S
R
P
S
S
D
S
F
Site 89
S1134
C
T
T
G
S
R
P
S
S
D
S
F
P
K
F
Site 90
S1135
T
T
G
S
R
P
S
S
D
S
F
P
K
F
V
Site 91
S1137
G
S
R
P
S
S
D
S
F
P
K
F
V
V
T
Site 92
T1144
S
F
P
K
F
V
V
T
A
K
N
E
D
R
D
Site 93
S1153
K
N
E
D
R
D
P
S
L
A
L
W
V
K
Q
Site 94
T1179
I
H
R
A
Y
K
H
T
V
L
V
N
S
E
R
Site 95
S1184
K
H
T
V
L
V
N
S
E
R
L
Y
L
P
L
Site 96
Y1188
L
V
N
S
E
R
L
Y
L
P
L
K
L
G
Q
Site 97
T1228
W
K
T
F
L
S
I
T
V
P
R
S
M
Q
N
Site 98
S1232
L
S
I
T
V
P
R
S
M
Q
N
S
T
Y
G
Site 99
S1236
V
P
R
S
M
Q
N
S
T
Y
G
L
C
G
R
Site 100
Y1238
R
S
M
Q
N
S
T
Y
G
L
C
G
R
Y
N
Site 101
S1269
S
V
N
E
F
G
Q
S
W
V
K
R
D
T
F
Site 102
S1287
G
C
G
D
R
C
P
S
C
A
K
V
E
G
F
Site 103
S1302
S
K
V
Q
Q
L
C
S
L
I
P
N
Q
N
A
Site 104
T1354
N
Y
A
S
T
C
Q
T
Q
G
I
T
V
T
G
Site 105
S1376
T
V
T
C
P
P
N
S
H
Y
E
S
C
V
S
Site 106
Y1378
T
C
P
P
N
S
H
Y
E
S
C
V
S
V
C
Site 107
S1380
P
P
N
S
H
Y
E
S
C
V
S
V
C
Q
P
Site 108
Y1412
G
C
H
C
D
A
G
Y
V
L
N
G
K
S
C
Site 109
Y1428
L
P
H
S
C
G
C
Y
S
D
G
K
Y
Y
E
Site 110
Y1433
G
C
Y
S
D
G
K
Y
Y
E
P
K
Q
L
F
Site 111
Y1434
C
Y
S
D
G
K
Y
Y
E
P
K
Q
L
F
W
Site 112
S1466
C
D
P
R
Q
C
K
S
D
E
E
C
A
L
R
Site 113
T1484
R
G
C
F
S
T
K
T
S
Y
C
L
A
A
G
Site 114
T1561
I
L
I
N
D
R
N
T
V
K
V
N
G
T
Q
Site 115
Y1599
T
S
P
D
I
Q
I
Y
Y
N
G
F
N
V
I
Site 116
Y1600
S
P
D
I
Q
I
Y
Y
N
G
F
N
V
I
K
Site 117
S1609
G
F
N
V
I
K
I
S
I
S
E
R
L
Q
N
Site 118
S1611
N
V
I
K
I
S
I
S
E
R
L
Q
N
K
V
Site 119
T1630
G
N
F
N
G
D
L
T
D
D
Y
V
T
L
R
Site 120
Y1633
N
G
D
L
T
D
D
Y
V
T
L
R
G
K
P
Site 121
T1635
D
L
T
D
D
Y
V
T
L
R
G
K
P
V
V
Site 122
S1664
Q
K
R
P
L
A
P
S
C
N
E
L
Q
F
S
Site 123
Y1673
N
E
L
Q
F
S
Q
Y
A
A
M
C
D
N
V
Site 124
Y1690
Q
K
M
Q
G
D
G
Y
C
L
K
L
T
D
M
Site 125
Y1718
L
P
F
Y
E
S
C
Y
L
D
G
C
Y
N
H
Site 126
Y1723
S
C
Y
L
D
G
C
Y
N
H
K
K
F
Q
L
Site 127
S1733
K
K
F
Q
L
C
G
S
L
A
A
Y
G
E
A
Site 128
S1743
A
Y
G
E
A
C
R
S
F
G
I
L
S
T
E
Site 129
S1748
C
R
S
F
G
I
L
S
T
E
W
I
E
K
E
Site 130
Y1792
G
C
I
E
P
P
P
Y
G
N
N
S
H
D
I
Site 131
T1838
R
I
N
D
R
Q
C
T
G
I
E
G
E
D
F
Site 132
Y1870
S
N
G
T
H
I
M
Y
K
N
T
L
W
I
E
Site 133
T1882
W
I
E
S
A
N
N
T
G
N
I
I
T
R
D
Site 134
T1891
N
I
I
T
R
D
R
T
I
N
V
E
F
S
C
Site 135
Y1937
F
I
T
K
M
A
L
Y
K
N
A
S
Y
K
H
Site 136
Y1942
A
L
Y
K
N
A
S
Y
K
H
P
Y
R
Q
G
Site 137
Y1981
I
L
T
L
N
K
C
Y
A
T
P
T
R
D
S
Site 138
T1983
T
L
N
K
C
Y
A
T
P
T
R
D
S
N
D
Site 139
S1988
Y
A
T
P
T
R
D
S
N
D
K
L
R
Y
F
Site 140
Y1994
D
S
N
D
K
L
R
Y
F
I
I
E
G
G
C
Site 141
Y2050
S
L
C
D
S
E
K
Y
S
C
K
I
T
C
P
Site 142
T2055
E
K
Y
S
C
K
I
T
C
P
H
N
S
R
I
Site 143
S2060
K
I
T
C
P
H
N
S
R
I
A
T
D
Y
T
Site 144
T2064
P
H
N
S
R
I
A
T
D
Y
T
K
E
P
K
Site 145
Y2066
N
S
R
I
A
T
D
Y
T
K
E
P
K
E
Q
Site 146
T2067
S
R
I
A
T
D
Y
T
K
E
P
K
E
Q
I
Site 147
S2076
E
P
K
E
Q
I
I
S
V
G
P
I
R
R
K
Site 148
T2099
G
G
C
E
Q
I
C
T
S
R
V
D
G
P
L
Site 149
S2120
T
L
Q
E
D
G
K
S
C
R
A
S
N
S
S
Site 150
S2124
D
G
K
S
C
R
A
S
N
S
S
M
E
L
Q
Site 151
S2126
K
S
C
R
A
S
N
S
S
M
E
L
Q
V
W
Site 152
S2127
S
C
R
A
S
N
S
S
M
E
L
Q
V
W
T
Site 153
Y2149
I
S
L
W
H
F
V
Y
K
S
G
T
T
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation