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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KATNA1
Full Name:
Katanin p60 ATPase-containing subunit A1
Alias:
EC 3.6.4.3; Katanin p60 A1; Katanin p60 ATPase-containing A1; KTNA1
Type:
Enzyme - Hydrolase
Mass (Da):
55965
Number AA:
491
UniProt ID:
O75449
International Prot ID:
IPI00013075
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005874
GO:0000922
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008017
GO:0008568
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0051329
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
N
V
K
L
A
R
E
Y
A
L
L
G
N
Y
D
Site 2
Y22
E
Y
A
L
L
G
N
Y
D
S
A
M
V
Y
Y
Site 3
Y28
N
Y
D
S
A
M
V
Y
Y
Q
G
V
L
D
Q
Site 4
Y29
Y
D
S
A
M
V
Y
Y
Q
G
V
L
D
Q
M
Site 5
Y39
V
L
D
Q
M
N
K
Y
L
Y
S
V
K
D
T
Site 6
Y41
D
Q
M
N
K
Y
L
Y
S
V
K
D
T
Y
L
Site 7
Y47
L
Y
S
V
K
D
T
Y
L
Q
Q
K
W
Q
Q
Site 8
T72
H
V
K
D
I
M
K
T
L
E
S
F
K
L
D
Site 9
S75
D
I
M
K
T
L
E
S
F
K
L
D
S
T
P
Site 10
S80
L
E
S
F
K
L
D
S
T
P
L
K
A
A
Q
Site 11
T81
E
S
F
K
L
D
S
T
P
L
K
A
A
Q
H
Site 12
S93
A
Q
H
D
L
P
A
S
E
G
E
V
W
S
M
Site 13
S99
A
S
E
G
E
V
W
S
M
P
V
P
V
E
R
Site 14
S109
V
P
V
E
R
R
P
S
P
G
P
R
K
R
Q
Site 15
S117
P
G
P
R
K
R
Q
S
S
Q
Y
S
D
P
K
Site 16
S118
G
P
R
K
R
Q
S
S
Q
Y
S
D
P
K
S
Site 17
Y120
R
K
R
Q
S
S
Q
Y
S
D
P
K
S
H
G
Site 18
S121
K
R
Q
S
S
Q
Y
S
D
P
K
S
H
G
N
Site 19
S125
S
Q
Y
S
D
P
K
S
H
G
N
R
P
S
T
Site 20
S131
K
S
H
G
N
R
P
S
T
T
V
R
V
H
R
Site 21
T132
S
H
G
N
R
P
S
T
T
V
R
V
H
R
S
Site 22
T133
H
G
N
R
P
S
T
T
V
R
V
H
R
S
S
Site 23
S140
T
V
R
V
H
R
S
S
A
Q
N
V
H
N
D
Site 24
S170
G
R
E
E
K
N
K
S
P
A
A
V
T
E
P
Site 25
T179
A
A
V
T
E
P
E
T
N
K
F
D
S
T
G
Site 26
T185
E
T
N
K
F
D
S
T
G
Y
D
K
D
L
V
Site 27
S201
A
L
E
R
D
I
I
S
Q
N
P
N
V
R
W
Site 28
T269
V
A
T
E
C
K
T
T
F
F
N
V
S
S
S
Site 29
S274
K
T
T
F
F
N
V
S
S
S
T
L
T
S
K
Site 30
S275
T
T
F
F
N
V
S
S
S
T
L
T
S
K
Y
Site 31
S276
T
F
F
N
V
S
S
S
T
L
T
S
K
Y
R
Site 32
T279
N
V
S
S
S
T
L
T
S
K
Y
R
G
E
S
Site 33
S280
V
S
S
S
T
L
T
S
K
Y
R
G
E
S
E
Site 34
Y282
S
S
T
L
T
S
K
Y
R
G
E
S
E
K
L
Site 35
S286
T
S
K
Y
R
G
E
S
E
K
L
V
R
L
L
Site 36
S315
D
E
I
D
S
I
C
S
R
R
G
T
S
E
E
Site 37
T319
S
I
C
S
R
R
G
T
S
E
E
H
E
A
S
Site 38
S320
I
C
S
R
R
G
T
S
E
E
H
E
A
S
R
Site 39
S326
T
S
E
E
H
E
A
S
R
R
V
K
A
E
L
Site 40
S350
T
S
E
N
D
D
P
S
K
M
V
M
V
L
A
Site 41
Y378
R
R
L
E
K
R
I
Y
I
P
L
P
S
A
K
Site 42
S394
R
E
E
L
L
R
I
S
L
R
E
L
E
L
A
Site 43
S408
A
D
D
V
D
L
A
S
I
A
E
N
M
E
G
Site 44
T422
G
Y
S
G
A
D
I
T
N
V
C
R
D
A
S
Site 45
S429
T
N
V
C
R
D
A
S
L
M
A
M
R
R
R
Site 46
T441
R
R
R
I
E
G
L
T
P
E
E
I
R
N
L
Site 47
S449
P
E
E
I
R
N
L
S
K
E
E
M
H
M
P
Site 48
S470
E
M
A
L
K
K
V
S
K
S
V
S
A
A
D
Site 49
S472
A
L
K
K
V
S
K
S
V
S
A
A
D
I
E
Site 50
S474
K
K
V
S
K
S
V
S
A
A
D
I
E
R
Y
Site 51
Y481
S
A
A
D
I
E
R
Y
E
K
W
I
F
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation