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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RDH16
Full Name:
Retinol dehydrogenase 16
Alias:
Microsomal NAD+ dependent retinol dehydrogenase 4; Microsomal NAD+-dependent retinol dehydrogenase 4; Retinol dehydrogenase 16 (all-trans); RODH4; RODH-4; SDR9C8; Short chain dehydrogenase/reductase family 9C, member 8; Sterol/retinol dehydrogenase
Type:
Endoplasmic reticulum; EC 1.1.-.-; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol
Mass (Da):
35655
Number AA:
317
UniProt ID:
O75452
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
GO:0005792
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0009055
GO:0004745
PhosphoSite+
KinaseNET
Biological Process:
GO:0006629
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
L
A
V
F
V
G
L
Y
Y
L
L
H
W
Y
R
Site 2
Y18
L
Y
Y
L
L
H
W
Y
R
E
R
Q
V
L
S
Site 3
S25
Y
R
E
R
Q
V
L
S
H
L
R
D
K
Y
V
Site 4
Y31
L
S
H
L
R
D
K
Y
V
F
I
T
G
C
D
Site 5
T35
R
D
K
Y
V
F
I
T
G
C
D
S
G
F
G
Site 6
T73
A
E
Q
L
R
G
Q
T
S
D
R
L
E
T
V
Site 7
S74
E
Q
L
R
G
Q
T
S
D
R
L
E
T
V
T
Site 8
T79
Q
T
S
D
R
L
E
T
V
T
L
D
V
T
K
Site 9
T81
S
D
R
L
E
T
V
T
L
D
V
T
K
T
E
Site 10
S163
R
G
R
V
V
N
V
S
S
V
M
G
R
V
S
Site 11
Y181
G
G
Y
C
I
S
K
Y
G
V
E
A
F
S
D
Site 12
S187
K
Y
G
V
E
A
F
S
D
S
L
R
R
E
L
Site 13
S189
G
V
E
A
F
S
D
S
L
R
R
E
L
S
Y
Site 14
S195
D
S
L
R
R
E
L
S
Y
F
G
V
K
V
A
Site 15
Y196
S
L
R
R
E
L
S
Y
F
G
V
K
V
A
M
Site 16
T211
I
E
P
G
Y
F
K
T
A
V
T
S
K
E
R
Site 17
S215
Y
F
K
T
A
V
T
S
K
E
R
F
L
K
S
Site 18
S222
S
K
E
R
F
L
K
S
F
L
E
I
W
D
R
Site 19
S231
L
E
I
W
D
R
S
S
P
E
V
K
E
A
Y
Site 20
Y238
S
P
E
V
K
E
A
Y
G
E
K
F
V
A
D
Site 21
Y246
G
E
K
F
V
A
D
Y
K
K
S
A
E
Q
M
Site 22
T258
E
Q
M
E
Q
K
C
T
Q
D
L
S
L
V
T
Site 23
Y281
A
C
H
P
R
T
R
Y
S
A
G
W
D
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation