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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERLIN1
Full Name:
Erlin-1
Alias:
Endoplasmic reticulum lipid raft-associated protein 1; ERLN1; KE04; KEO4; SPFH domain family, member 1; SPFH domain-containing protein 1
Type:
Uncharacterized membrane protein. Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
Mass (Da):
38926
Number AA:
346
UniProt ID:
O75477
International Prot ID:
IPI00007940
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005789
GO:0016021
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030433
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T42
Y
R
G
G
A
L
L
T
S
P
S
G
P
G
Y
Site 2
S43
R
G
G
A
L
L
T
S
P
S
G
P
G
Y
H
Site 3
S61
P
F
I
T
T
F
R
S
V
Q
T
T
L
Q
T
Site 4
T65
T
F
R
S
V
Q
T
T
L
Q
T
D
E
V
K
Site 5
Y107
V
F
D
I
V
R
N
Y
T
A
D
Y
D
K
T
Site 6
T108
F
D
I
V
R
N
Y
T
A
D
Y
D
K
T
L
Site 7
Y111
V
R
N
Y
T
A
D
Y
D
K
T
L
I
F
N
Site 8
T171
T
I
Q
A
V
R
V
T
K
P
K
I
P
E
A
Site 9
S243
K
E
T
E
K
R
I
S
E
I
E
D
A
A
F
Site 10
Y262
K
A
K
A
D
A
E
Y
Y
A
A
H
K
Y
A
Site 11
Y268
E
Y
Y
A
A
H
K
Y
A
T
S
N
K
H
K
Site 12
T277
T
S
N
K
H
K
L
T
P
E
Y
L
E
L
K
Site 13
Y280
K
H
K
L
T
P
E
Y
L
E
L
K
K
Y
Q
Site 14
Y286
E
Y
L
E
L
K
K
Y
Q
A
I
A
S
N
S
Site 15
S291
K
K
Y
Q
A
I
A
S
N
S
K
I
Y
F
G
Site 16
Y296
I
A
S
N
S
K
I
Y
F
G
S
N
I
P
N
Site 17
S309
P
N
M
F
V
D
S
S
C
A
L
K
Y
S
D
Site 18
Y314
D
S
S
C
A
L
K
Y
S
D
I
R
T
G
R
Site 19
S315
S
S
C
A
L
K
Y
S
D
I
R
T
G
R
E
Site 20
T319
L
K
Y
S
D
I
R
T
G
R
E
S
S
L
P
Site 21
S323
D
I
R
T
G
R
E
S
S
L
P
S
K
E
A
Site 22
S324
I
R
T
G
R
E
S
S
L
P
S
K
E
A
L
Site 23
S327
G
R
E
S
S
L
P
S
K
E
A
L
E
P
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation