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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FUSIP1
Full Name:
Serine/arginine-rich splicing factor 10
Alias:
40 kDa SR-repressor protein; FUS interacting serine-arginine rich protein 1; FUSI; FUSIP; FUSIP2; SFRS13; Splicing factor SRp38; Splicing factor, arginine/serine-rich 13; Splicing factor, arginine/serine-rich 13A; SRp38; SRrp40; TASR; TASR1; TASR2; TLS-associated protein with Ser-Arg repeats; TLS-associated protein with SR repeats; TLS-associated serine-arginine protein; TLS-associated SR protein
Type:
RNA binding protein
Mass (Da):
31301
Number AA:
262
UniProt ID:
O75494
International Prot ID:
IPI00074587
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0050733
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0000244
GO:0016482
GO:0006406
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
R
Y
L
R
P
P
N
T
S
L
F
V
R
N
V
Site 2
S11
Y
L
R
P
P
N
T
S
L
F
V
R
N
V
A
Site 3
T21
V
R
N
V
A
D
D
T
R
S
E
D
L
R
R
Site 4
S23
N
V
A
D
D
T
R
S
E
D
L
R
R
E
F
Site 5
Y33
L
R
R
E
F
G
R
Y
G
P
I
V
D
V
Y
Site 6
Y40
Y
G
P
I
V
D
V
Y
V
P
L
D
F
Y
T
Site 7
Y46
V
Y
V
P
L
D
F
Y
T
R
R
P
R
G
F
Site 8
T47
Y
V
P
L
D
F
Y
T
R
R
P
R
G
F
A
Site 9
Y55
R
R
P
R
G
F
A
Y
V
Q
F
E
D
V
R
Site 10
T92
F
A
Q
G
D
R
K
T
P
N
Q
M
K
A
K
Site 11
Y105
A
K
E
G
R
N
V
Y
S
S
S
R
Y
D
D
Site 12
S106
K
E
G
R
N
V
Y
S
S
S
R
Y
D
D
Y
Site 13
S107
E
G
R
N
V
Y
S
S
S
R
Y
D
D
Y
D
Site 14
S108
G
R
N
V
Y
S
S
S
R
Y
D
D
Y
D
R
Site 15
Y110
N
V
Y
S
S
S
R
Y
D
D
Y
D
R
Y
R
Site 16
Y113
S
S
S
R
Y
D
D
Y
D
R
Y
R
R
S
R
Site 17
Y116
R
Y
D
D
Y
D
R
Y
R
R
S
R
S
R
S
Site 18
S119
D
Y
D
R
Y
R
R
S
R
S
R
S
Y
E
R
Site 19
S121
D
R
Y
R
R
S
R
S
R
S
Y
E
R
R
R
Site 20
S123
Y
R
R
S
R
S
R
S
Y
E
R
R
R
S
R
Site 21
Y124
R
R
S
R
S
R
S
Y
E
R
R
R
S
R
S
Site 22
S129
R
S
Y
E
R
R
R
S
R
S
R
S
F
D
Y
Site 23
S131
Y
E
R
R
R
S
R
S
R
S
F
D
Y
N
Y
Site 24
S133
R
R
R
S
R
S
R
S
F
D
Y
N
Y
R
R
Site 25
Y136
S
R
S
R
S
F
D
Y
N
Y
R
R
S
Y
S
Site 26
Y138
S
R
S
F
D
Y
N
Y
R
R
S
Y
S
P
R
Site 27
S141
F
D
Y
N
Y
R
R
S
Y
S
P
R
N
S
R
Site 28
Y142
D
Y
N
Y
R
R
S
Y
S
P
R
N
S
R
P
Site 29
S143
Y
N
Y
R
R
S
Y
S
P
R
N
S
R
P
T
Site 30
S147
R
S
Y
S
P
R
N
S
R
P
T
G
R
P
R
Site 31
T150
S
P
R
N
S
R
P
T
G
R
P
R
R
S
R
Site 32
S156
P
T
G
R
P
R
R
S
R
S
H
S
D
N
D
Site 33
S158
G
R
P
R
R
S
R
S
H
S
D
N
D
R
P
Site 34
S160
P
R
R
S
R
S
H
S
D
N
D
R
F
K
H
Site 35
S171
R
F
K
H
R
N
R
S
F
S
R
S
K
S
N
Site 36
S173
K
H
R
N
R
S
F
S
R
S
K
S
N
S
R
Site 37
S175
R
N
R
S
F
S
R
S
K
S
N
S
R
S
R
Site 38
S177
R
S
F
S
R
S
K
S
N
S
R
S
R
S
K
Site 39
S179
F
S
R
S
K
S
N
S
R
S
R
S
K
S
Q
Site 40
S181
R
S
K
S
N
S
R
S
R
S
K
S
Q
P
K
Site 41
S183
K
S
N
S
R
S
R
S
K
S
Q
P
K
K
E
Site 42
S185
N
S
R
S
R
S
K
S
Q
P
K
K
E
M
K
Site 43
S195
K
K
E
M
K
A
K
S
R
S
R
S
A
S
H
Site 44
S197
E
M
K
A
K
S
R
S
R
S
A
S
H
T
K
Site 45
S199
K
A
K
S
R
S
R
S
A
S
H
T
K
T
R
Site 46
S201
K
S
R
S
R
S
A
S
H
T
K
T
R
G
T
Site 47
T203
R
S
R
S
A
S
H
T
K
T
R
G
T
S
K
Site 48
T205
R
S
A
S
H
T
K
T
R
G
T
S
K
T
D
Site 49
T208
S
H
T
K
T
R
G
T
S
K
T
D
S
K
T
Site 50
S209
H
T
K
T
R
G
T
S
K
T
D
S
K
T
H
Site 51
T211
K
T
R
G
T
S
K
T
D
S
K
T
H
Y
K
Site 52
S213
R
G
T
S
K
T
D
S
K
T
H
Y
K
S
G
Site 53
T215
T
S
K
T
D
S
K
T
H
Y
K
S
G
S
R
Site 54
Y217
K
T
D
S
K
T
H
Y
K
S
G
S
R
Y
E
Site 55
S219
D
S
K
T
H
Y
K
S
G
S
R
Y
E
K
E
Site 56
S221
K
T
H
Y
K
S
G
S
R
Y
E
K
E
S
R
Site 57
Y223
H
Y
K
S
G
S
R
Y
E
K
E
S
R
K
K
Site 58
S227
G
S
R
Y
E
K
E
S
R
K
K
E
P
P
R
Site 59
S235
R
K
K
E
P
P
R
S
K
S
Q
S
R
S
Q
Site 60
S237
K
E
P
P
R
S
K
S
Q
S
R
S
Q
S
R
Site 61
S239
P
P
R
S
K
S
Q
S
R
S
Q
S
R
S
R
Site 62
S241
R
S
K
S
Q
S
R
S
Q
S
R
S
R
S
K
Site 63
S243
K
S
Q
S
R
S
Q
S
R
S
R
S
K
S
R
Site 64
S245
Q
S
R
S
Q
S
R
S
R
S
K
S
R
S
R
Site 65
S247
R
S
Q
S
R
S
R
S
K
S
R
S
R
S
W
Site 66
S249
Q
S
R
S
R
S
K
S
R
S
R
S
W
T
S
Site 67
S251
R
S
R
S
K
S
R
S
R
S
W
T
S
P
K
Site 68
S253
R
S
K
S
R
S
R
S
W
T
S
P
K
S
S
Site 69
T255
K
S
R
S
R
S
W
T
S
P
K
S
S
G
H
Site 70
S256
S
R
S
R
S
W
T
S
P
K
S
S
G
H
_
Site 71
S259
R
S
W
T
S
P
K
S
S
G
H
_
_
_
_
Site 72
S260
S
W
T
S
P
K
S
S
G
H
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation