PhosphoNET

           
Protein Info 
   
Short Name:  TNFRSF21
Full Name:  Tumor necrosis factor receptor superfamily member 21
Alias:  Death receptor 6; TNFR-related death receptor 6; TNR21; Tumor necrosis factor receptor superfamily member 21; Tumor necrosis factor receptor superfamily, 21; Tumor necrosis factor receptor superfamily, member 21
Type:  Apoptosis; Receptor, cytokine
Mass (Da):  71845
Number AA:  655
UniProt ID:  O75509
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0004872   PhosphoSite+ KinaseNET
Biological Process:  GO:0006915  GO:0007165   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S4____MGTSPSSSTAL
Site 2S6__MGTSPSSSTALAS
Site 3S7_MGTSPSSSTALASC
Site 4S8MGTSPSSSTALASCS
Site 5T9GTSPSSSTALASCSR
Site 6S13SSSTALASCSRIARR
Site 7S15STALASCSRIARRAT
Site 8T22SRIARRATATMIAGS
Site 9T24IARRATATMIAGSLL
Site 10S177QCARGTFSDVPSSVM
Site 11S181GTFSDVPSSVMKCKA
Site 12S182TFSDVPSSVMKCKAY
Site 13S373VVCSIRKSSRTLKKG
Site 14S374VCSIRKSSRTLKKGP
Site 15T376SIRKSSRTLKKGPRQ
Site 16S386KGPRQDPSAIVEKAG
Site 17S397EKAGLKKSMTPTQNR
Site 18T399AGLKKSMTPTQNREK
Site 19T401LKKSMTPTQNREKWI
Site 20Y434GSQWKDIYQFLCNAS
Site 21S441YQFLCNASEREVAAF
Site 22Y452VAAFSNGYTADHERA
Site 23T453AAFSNGYTADHERAY
Site 24Y460TADHERAYAALQHWT
Site 25S480ASLAQLISALRQHRR
Site 26T502RGLMEDTTQLETDKL
Site 27S514DKLALPMSPSPLSPS
Site 28S519PMSPSPLSPSPIPSP
Site 29S521SPSPLSPSPIPSPNA
Site 30S525LSPSPIPSPNAKLEN
Site 31T537LENSALLTVEPSPQD
Site 32S541ALLTVEPSPQDKNKG
Site 33S554KGFFVDESEPLLRCD
Site 34S562EPLLRCDSTSSGSSA
Site 35T563PLLRCDSTSSGSSAL
Site 36S564LLRCDSTSSGSSALS
Site 37S565LRCDSTSSGSSALSR
Site 38S567CDSTSSGSSALSRNG
Site 39S568DSTSSGSSALSRNGS
Site 40S571SSGSSALSRNGSFIT
Site 41S575SALSRNGSFITKEKK
Site 42T584ITKEKKDTVLRQVRL
Site 43S636FEIIGVKSQEASQTL
Site 44S640GVKSQEASQTLLDSV
Site 45T642KSQEASQTLLDSVYS
Site 46S646ASQTLLDSVYSHLPD
Site 47Y648QTLLDSVYSHLPDLL
Site 48S649TLLDSVYSHLPDLL_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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