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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PECI
Full Name:
Peroxisomal 3,2-trans-enoyl-CoA isomerase
Alias:
ACBD2; Acyl-Coenzyme A binding domain containing 2; D3,D2-enoyl-CoA isomerase; DBI-related protein 1; Dodecenoyl-CoA isomerase; DRS1; DRS-1; HCA88; Hepatocellular carcinoma-associated antigen 88; Peroxisomal 3,2-trans-enoyl-CoA isomerase; Peroxisomal D3,D2-enoyl-CoA isomerase
Type:
EC 5.3.3.8; Lipid Metabolism - fatty acid; Isomerase
Mass (Da):
39609
Number AA:
359
UniProt ID:
O75521
International Prot ID:
IPI00419263
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005782
Uniprot
OncoNet
Molecular Function:
GO:0000062
GO:0004165
PhosphoSite+
KinaseNET
Biological Process:
GO:0006631
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
A
W
R
L
A
R
R
S
C
P
S
S
L
Q
V
Site 2
S17
L
A
R
R
S
C
P
S
S
L
Q
V
T
S
F
Site 3
S18
A
R
R
S
C
P
S
S
L
Q
V
T
S
F
P
Site 4
T34
V
Q
L
H
M
N
R
T
A
M
R
A
S
Q
K
Site 5
S39
N
R
T
A
M
R
A
S
Q
K
D
F
E
N
S
Site 6
Y66
N
E
V
K
L
K
L
Y
A
L
Y
K
Q
A
T
Site 7
Y111
K
E
A
A
R
Q
N
Y
V
D
L
V
S
S
L
Site 8
S116
Q
N
Y
V
D
L
V
S
S
L
S
P
S
L
E
Site 9
S117
N
Y
V
D
L
V
S
S
L
S
P
S
L
E
S
Site 10
S119
V
D
L
V
S
S
L
S
P
S
L
E
S
S
S
Site 11
S121
L
V
S
S
L
S
P
S
L
E
S
S
S
Q
V
Site 12
S125
L
S
P
S
L
E
S
S
S
Q
V
E
P
G
T
Site 13
S126
S
P
S
L
E
S
S
S
Q
V
E
P
G
T
D
Site 14
T132
S
S
Q
V
E
P
G
T
D
R
K
S
T
G
F
Site 15
S136
E
P
G
T
D
R
K
S
T
G
F
E
T
L
V
Site 16
T137
P
G
T
D
R
K
S
T
G
F
E
T
L
V
V
Site 17
T141
R
K
S
T
G
F
E
T
L
V
V
T
S
E
D
Site 18
T151
V
T
S
E
D
G
I
T
K
I
M
F
N
R
P
Site 19
T166
K
K
K
N
A
I
N
T
E
M
Y
H
E
I
M
Site 20
Y169
N
A
I
N
T
E
M
Y
H
E
I
M
R
A
L
Site 21
S180
M
R
A
L
K
A
A
S
K
D
D
S
I
I
T
Site 22
T187
S
K
D
D
S
I
I
T
V
L
T
G
N
G
D
Site 23
Y195
V
L
T
G
N
G
D
Y
Y
S
S
G
N
D
L
Site 24
Y196
L
T
G
N
G
D
Y
Y
S
S
G
N
D
L
T
Site 25
S197
T
G
N
G
D
Y
Y
S
S
G
N
D
L
T
N
Site 26
T203
Y
S
S
G
N
D
L
T
N
F
T
D
I
P
P
Site 27
T206
G
N
D
L
T
N
F
T
D
I
P
P
G
G
V
Site 28
S263
L
F
D
A
V
Y
A
S
D
R
A
T
F
H
T
Site 29
T267
V
Y
A
S
D
R
A
T
F
H
T
P
F
S
H
Site 30
T270
S
D
R
A
T
F
H
T
P
F
S
H
L
G
Q
Site 31
S273
A
T
F
H
T
P
F
S
H
L
G
Q
S
P
E
Site 32
S278
P
F
S
H
L
G
Q
S
P
E
G
C
S
S
Y
Site 33
S283
G
Q
S
P
E
G
C
S
S
Y
T
F
P
K
I
Site 34
S284
Q
S
P
E
G
C
S
S
Y
T
F
P
K
I
M
Site 35
Y285
S
P
E
G
C
S
S
Y
T
F
P
K
I
M
S
Site 36
T286
P
E
G
C
S
S
Y
T
F
P
K
I
M
S
P
Site 37
S292
Y
T
F
P
K
I
M
S
P
A
K
A
T
E
M
Site 38
S324
V
T
E
V
F
P
D
S
T
F
Q
K
E
V
W
Site 39
T325
T
E
V
F
P
D
S
T
F
Q
K
E
V
W
T
Site 40
S348
P
P
N
A
L
R
I
S
K
E
V
I
R
K
R
Site 41
S377
V
L
Q
G
R
W
L
S
D
E
C
T
N
A
V
Site 42
S389
N
A
V
V
N
F
L
S
R
K
S
K
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation